BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 27037775)

  • 21. Combining X-ray crystallography and molecular modeling toward the optimization of pyrazolo[3,4-d]pyrimidines as potent c-Src inhibitors active in vivo against neuroblastoma.
    Tintori C; Fallacara AL; Radi M; Zamperini C; Dreassi E; Crespan E; Maga G; Schenone S; Musumeci F; Brullo C; Richters A; Gasparrini F; Angelucci A; Festuccia C; Delle Monache S; Rauh D; Botta M
    J Med Chem; 2015 Jan; 58(1):347-61. PubMed ID: 25469771
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells.
    Nam S; Kim D; Cheng JQ; Zhang S; Lee JH; Buettner R; Mirosevich J; Lee FY; Jove R
    Cancer Res; 2005 Oct; 65(20):9185-9. PubMed ID: 16230377
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK; Wang ZL; Pan ST; Ding HQ; Au GH; He ZX; Zhou ZW; Xiao G; Yang YX; Zhang X; Yang T; Chen XW; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Suppression of autophagy sensitizes multidrug resistant cells towards Src tyrosine kinase specific inhibitor PP2.
    Ahn JH; Lee M
    Cancer Lett; 2011 Nov; 310(2):188-97. PubMed ID: 21775053
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Inhibition of Src and p38 MAP kinases suppresses the change of claudin expression induced on dedifferentiation of primary cultured parotid acinar cells.
    Fujita-Yoshigaki J; Matsuki-Fukushima M; Sugiya H
    Am J Physiol Cell Physiol; 2008 Mar; 294(3):C774-85. PubMed ID: 18234848
    [TBL] [Abstract][Full Text] [Related]  

  • 26. p21-activated kinases as viable therapeutic targets for the treatment of high-risk Ewing sarcoma.
    Qasim SL; Sierra L; Shuck R; Kurenbekova L; Patel TD; Rajapakshe K; Wulff J; Nakahata K; Kim HR; Landesman Y; Unger TJ; Coarfa C; Yustein JT
    Oncogene; 2021 Feb; 40(6):1176-1190. PubMed ID: 33414491
    [TBL] [Abstract][Full Text] [Related]  

  • 27. IL6 secreted by Ewing sarcoma tumor microenvironment confers anti-apoptotic and cell-disseminating paracrine responses in Ewing sarcoma cells.
    Lissat A; Joerschke M; Shinde DA; Braunschweig T; Meier A; Makowska A; Bortnick R; Henneke P; Herget G; Gorr TA; Kontny U
    BMC Cancer; 2015 Jul; 15():552. PubMed ID: 26215971
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Src family tyrosine kinases participate in insulin-like growth factor I mitogenic signaling in 3T3-L1 cells.
    Boney CM; Sekimoto H; Gruppuso PA; Frackelton AR
    Cell Growth Differ; 2001 Jul; 12(7):379-86. PubMed ID: 11457735
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Contribution of MEK/MAPK and PI3-K signaling pathway to the malignant behavior of Ewing's sarcoma cells: therapeutic prospects.
    Benini S; Manara MC; Cerisano V; Perdichizzi S; Strammiello R; Serra M; Picci P; Scotlandi K
    Int J Cancer; 2004 Jan; 108(3):358-66. PubMed ID: 14648701
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment.
    Molinari A; Fallacara AL; Di Maria S; Zamperini C; Poggialini F; Musumeci F; Schenone S; Angelucci A; Colapietro A; Crespan E; Kissova M; Maga G; Botta M
    Bioorg Med Chem Lett; 2018 Nov; 28(21):3454-3457. PubMed ID: 30262428
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Dasatinib, a small molecule inhibitor of the Src kinase, reduces the growth and activates apoptosis in pre-neoplastic Barrett's esophagus cell lines: evidence for a noninvasive treatment of high-grade dysplasia.
    Inge LJ; Fowler AJ; Paquette KM; Richer AL; Tran N; Bremner RM
    J Thorac Cardiovasc Surg; 2013 Feb; 145(2):531-8. PubMed ID: 23142123
    [TBL] [Abstract][Full Text] [Related]  

  • 32. SRC-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines.
    Zhang J; Kalyankrishna S; Wislez M; Thilaganathan N; Saigal B; Wei W; Ma L; Wistuba II; Johnson FM; Kurie JM
    Am J Pathol; 2007 Jan; 170(1):366-76. PubMed ID: 17200208
    [TBL] [Abstract][Full Text] [Related]  

  • 33. EphA2 receptor is a key player in the metastatic onset of Ewing sarcoma.
    Garcia-Monclús S; López-Alemany R; Almacellas-Rabaiget O; Herrero-Martín D; Huertas-Martinez J; Lagares-Tena L; Alba-Pavón P; Hontecillas-Prieto L; Mora J; de Álava E; Rello-Varona S; Giangrande PH; Tirado OM
    Int J Cancer; 2018 Sep; 143(5):1188-1201. PubMed ID: 29582409
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Epidermal Growth Factor Receptor Regulation of Ewing Sarcoma Cell Function.
    Kersting N; Kunzler Souza B; Araujo Vieira I; Pereira Dos Santos R; Brufatto Olguins D; José Gregianin L; Tesainer Brunetto A; Lunardi Brunetto A; Roesler R; Brunetto de Farias C; Schwartsmann G
    Oncology; 2018; 94(6):383-393. PubMed ID: 29539615
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Abrogation of signal transducer and activator of transcription 3 reactivation after Src kinase inhibition results in synergistic antitumor effects.
    Johnson FM; Saigal B; Tran H; Donato NJ
    Clin Cancer Res; 2007 Jul; 13(14):4233-44. PubMed ID: 17634553
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Targeting the yin and the yang: combined inhibition of the tyrosine kinase c-Src and the tyrosine phosphatase SHP-2 disrupts pancreatic cancer signaling and biology in vitro and tumor formation in vivo.
    Gomes EG; Connelly SF; Summy JM
    Pancreas; 2013 Jul; 42(5):795-806. PubMed ID: 23271399
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Antitumor activity of new pyrazolo[3,4-d]pyrimidine SRC kinase inhibitors in Burkitt lymphoma cell lines and its enhancement by WEE1 inhibition.
    Cozzi M; Giorgi F; Marcelli E; Pentimalli F; Forte IM; Schenone S; D'Urso V; De Falco G; Botta M; Giordano A; Indovina P
    Cell Cycle; 2012 Mar; 11(5):1029-39. PubMed ID: 22333592
    [TBL] [Abstract][Full Text] [Related]  

  • 38. SRC family kinase activity is up-regulated in hormone-refractory prostate cancer.
    Tatarov O; Mitchell TJ; Seywright M; Leung HY; Brunton VG; Edwards J
    Clin Cancer Res; 2009 May; 15(10):3540-9. PubMed ID: 19447874
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The inhibition of SRC family kinase suppresses pancreatic cancer cell proliferation, migration, and invasion.
    Je DW; O YM; Ji YG; Cho Y; Lee DH
    Pancreas; 2014 Jul; 43(5):768-76. PubMed ID: 24763074
    [TBL] [Abstract][Full Text] [Related]  

  • 40. WEE1 accumulation and deregulation of S-phase proteins mediate MLN4924 potent inhibitory effect on Ewing sarcoma cells.
    Mackintosh C; García-Domínguez DJ; Ordóñez JL; Ginel-Picardo A; Smith PG; Sacristán MP; de Álava E
    Oncogene; 2013 Mar; 32(11):1441-51. PubMed ID: 22641220
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.