BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 27042010)

  • 21. Nanomaterial-Facilitated Cyclin-Dependent Kinase 7 Inhibition Suppresses Gallbladder Cancer Progression via Targeting Transcriptional Addiction.
    Huang CS; Xu QC; Dai C; Wang L; Tien YC; Li F; Su Q; Huang XT; Wu J; Zhao W; Yin XY
    ACS Nano; 2021 Sep; 15(9):14744-14755. PubMed ID: 34405985
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Recent progress in development of cyclin-dependent kinase 7 inhibitors for cancer therapy.
    Liang H; Du J; Elhassan RM; Hou X; Fang H
    Expert Opin Investig Drugs; 2021 Jan; 30(1):61-76. PubMed ID: 33183110
    [No Abstract]   [Full Text] [Related]  

  • 23. Ceritinib increases sensitivity of AKT inhibitors to gastric cancer.
    Wang J; Xu X; Wang T; Guo Q; Dai X; Guo H; Zhang W; Cheng S; Chen X; Ding L
    Eur J Pharmacol; 2021 Apr; 896():173879. PubMed ID: 33515539
    [TBL] [Abstract][Full Text] [Related]  

  • 24. New thieno[3,2-d]pyrimidine-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents, EGFR and ARO inhibitors inducing apoptosis in breast cancer cells.
    Farghaly AM; AboulWafa OM; Baghdadi HH; Abd El Razik HA; Sedra SMY; Shamaa MM
    Bioorg Chem; 2021 Oct; 115():105208. PubMed ID: 34365057
    [TBL] [Abstract][Full Text] [Related]  

  • 25. CDK7 inhibitor THZ1 enhances antiPD-1 therapy efficacy via the p38α/MYC/PD-L1 signaling in non-small cell lung cancer.
    Wang J; Zhang R; Lin Z; Zhang S; Chen Y; Tang J; Hong J; Zhou X; Zong Y; Xu Y; Meng R; Xu S; Liu L; Zhang T; Yang K; Dong X; Wu G
    J Hematol Oncol; 2020 Jul; 13(1):99. PubMed ID: 32690037
    [TBL] [Abstract][Full Text] [Related]  

  • 26. CDK7 blockade suppresses super-enhancer-associated oncogenes in bladder cancer.
    Yang Y; Jiang D; Zhou Z; Xiong H; Yang X; Peng G; Xia W; Wang S; Lei H; Zhao J; Qian Z; Wu S; Pang J
    Cell Oncol (Dordr); 2021 Aug; 44(4):871-887. PubMed ID: 33905040
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Pyrazolo[3,4-d]pyrimidine-based dual EGFR T790M/HER2 inhibitors: Design, synthesis, structure-activity relationship and biological activity as potential antitumor and anticonvulsant agents.
    Lamie PF; El-Kalaawy AM; Abdel Latif NS; Rashed LA; Philoppes JN
    Eur J Med Chem; 2021 Mar; 214():113222. PubMed ID: 33545637
    [TBL] [Abstract][Full Text] [Related]  

  • 28. CDK7 Inhibition is Effective in all the Subtypes of Breast Cancer: Determinants of Response and Synergy with EGFR Inhibition.
    McDermott MSJ; Sharko AC; Munie J; Kassler S; Melendez T; Lim CU; Broude EV
    Cells; 2020 Mar; 9(3):. PubMed ID: 32155786
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Novel anticancer Hsp90 inhibitor disubstituted pyrazolyl 2-aminopyrimidine compound 7t induces cell cycle arrest and apoptosis via mitochondrial pathway in MCF-7 cells.
    Mettu A; Talla V; Naikal SJP
    Bioorg Med Chem Lett; 2020 Oct; 30(20):127470. PubMed ID: 32795627
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Mechanistic selectivity investigation and 2D-QSAR study of some new antiproliferative pyrazoles and pyrazolopyridines as potential CDK2 inhibitors.
    Hassan GS; Georgey HH; Mohammed EZ; George RF; Mahmoud WR; Omar FA
    Eur J Med Chem; 2021 Jun; 218():113389. PubMed ID: 33784602
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Discovery of a PROTAC targeting ALK with in vivo activity.
    Yan G; Zhong X; Yue L; Pu C; Shan H; Lan S; Zhou M; Hou X; Yang J; Li R
    Eur J Med Chem; 2021 Feb; 212():113150. PubMed ID: 33453602
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Discovery of coumarin derivatives as potent and selective cyclin-dependent kinase 9 (CDK9) inhibitors with high antitumour activity.
    Xu J; Li H; Wang X; Huang J; Li S; Liu C; Dong R; Zhu G; Duan C; Jiang F; Zhang Y; Zhu Y; Zhang T; Chen Y; Tang W; Lu T
    Eur J Med Chem; 2020 Aug; 200():112424. PubMed ID: 32447197
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Unveiling the promise of pyrimidine-modified CDK inhibitors in cancer treatment.
    Dubey R; Makhija R; Sharma A; Sahu A; Asati V
    Bioorg Chem; 2024 Aug; 149():107508. PubMed ID: 38850781
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7.
    Zhang H; Lin G; Jia S; Zhang Y; Wu J; Tao Y; Huang W; Song M; Ding K; Ma D; Fan M
    Eur J Med Chem; 2024 Jan; 263():115955. PubMed ID: 38000213
    [TBL] [Abstract][Full Text] [Related]  

  • 35. A patent review of cyclin-dependent kinase 7 (CDK7) inhibitors (2018-2022).
    Kovalová M; Baraka JP; Mik V; Jorda R; Luo L; Shao H; Kryštof V
    Expert Opin Ther Pat; 2023 Feb; 33(2):67-87. PubMed ID: 36975020
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Inhibition of CDK7-dependent transcriptional addiction is a potential therapeutic target in synovial sarcoma.
    Li X; Dean DC; Yuan J; Temple TH; Trent JC; Rosenberg AE; Yu S; Hornicek FJ; Duan Z
    Biomed Pharmacother; 2022 May; 149():112888. PubMed ID: 35367753
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Discovery of SHR5428 as a selective and noncovalent inhibitor of CDK7.
    Jia M; Wang W; Chen G; Wu T; Zhang T; Zhou Q; Yin J; Li J; Li X; Mao Y; Feng J; Hu M; Li X; He F
    Bioorg Med Chem Lett; 2023 Sep; 93():129429. PubMed ID: 37543274
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Design and Synthesis of Novel Macrocyclic Derivatives as Potent and Selective Cyclin-Dependent Kinase 7 Inhibitors.
    Niu P; Tao Y; Lin G; Xu H; Meng Q; Yang K; Huang W; Song M; Ding K; Ma D; Fan M
    J Med Chem; 2024 Apr; 67(8):6099-6118. PubMed ID: 38586950
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Cyclin-dependent kinase inhibitor therapy for hematologic malignancies.
    Bose P; Simmons GL; Grant S
    Expert Opin Investig Drugs; 2013 Jun; 22(6):723-38. PubMed ID: 23647051
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Control of Expression of Key Cell Cycle Enzymes Drives Cell Line-Specific Functions of CDK7 in Human PDAC Cells.
    Kolloch L; Kreinest T; Meisterernst M; Oeckinghaus A
    Int J Mol Sci; 2022 Jan; 23(2):. PubMed ID: 35054996
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.