BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 27043251)

  • 1. Dual leucine zipper kinase (MAP3K12) modulators: a patent review (2010-2015).
    Oetjen E; Lemcke T
    Expert Opin Ther Pat; 2016 May; 26(5):607-16. PubMed ID: 27043251
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Deciphering the multifunctional role of dual leucine zipper kinase (DLK) and its therapeutic potential in disease.
    Bu H; Li Z; Lu Y; Zhuang Z; Zhen Y; Zhang L
    Eur J Med Chem; 2023 Jul; 255():115404. PubMed ID: 37098296
    [TBL] [Abstract][Full Text] [Related]  

  • 3. c-Jun N-terminal kinase inhibitors: a patent review (2010 - 2014).
    Gehringer M; Muth F; Koch P; Laufer SA
    Expert Opin Ther Pat; 2015; 25(8):849-72. PubMed ID: 25991433
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dual Leucine Zipper Kinase Inhibitors for the Treatment of Neurodegeneration.
    Siu M; Sengupta Ghosh A; Lewcock JW
    J Med Chem; 2018 Sep; 61(18):8078-8087. PubMed ID: 29863360
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Critical Role for DLK and LZK in Axonal Repair in the Mammalian Spinal Cord.
    Saikia JM; Chavez-Martinez CL; Kim ND; Allibhoy S; Kim HJ; Simonyan L; Smadi S; Tsai KM; Romaus-Sanjurjo D; Jin Y; Zheng B
    J Neurosci; 2022 May; 42(18):3716-3732. PubMed ID: 35361703
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of dual leucine zipper kinase (DLK, MAP3K12) inhibitors with activity in neurodegeneration models.
    Patel S; Cohen F; Dean BJ; De La Torre K; Deshmukh G; Estrada AA; Ghosh AS; Gibbons P; Gustafson A; Huestis MP; Le Pichon CE; Lin H; Liu W; Liu X; Liu Y; Ly CQ; Lyssikatos JP; Ma C; Scearce-Levie K; Shin YG; Solanoy H; Stark KL; Wang J; Wang B; Zhao X; Lewcock JW; Siu M
    J Med Chem; 2015 Jan; 58(1):401-18. PubMed ID: 25341110
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of the Activity of the Dual Leucine Zipper Kinase by Distinct Mechanisms.
    Köster KA; Dethlefs M; Duque Escobar J; Oetjen E
    Cells; 2024 Feb; 13(4):. PubMed ID: 38391946
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Scaffold-Hopping and Structure-Based Discovery of Potent, Selective, And Brain Penetrant N-(1H-Pyrazol-3-yl)pyridin-2-amine Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12).
    Patel S; Harris SF; Gibbons P; Deshmukh G; Gustafson A; Kellar T; Lin H; Liu X; Liu Y; Liu Y; Ma C; Scearce-Levie K; Ghosh AS; Shin YG; Solanoy H; Wang J; Wang B; Yin J; Siu M; Lewcock JW
    J Med Chem; 2015 Oct; 58(20):8182-99. PubMed ID: 26431428
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The MAP3Ks DLK and LZK Direct Diverse Responses to Axon Damage in Zebrafish Peripheral Neurons.
    Adula KP; Shorey M; Chauhan V; Nassman K; Chen SF; Rolls MM; Sagasti A
    J Neurosci; 2022 Aug; 42(32):6195-6210. PubMed ID: 35840323
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dual Leucine Zipper Kinase Is Constitutively Active in the Adult Mouse Brain and Has Both Stress-Induced and Homeostatic Functions.
    Goodwani S; Fernandez C; Acton PJ; Buggia-Prevot V; McReynolds ML; Ma J; Hu CH; Hamby ME; Jiang Y; Le K; Soth MJ; Jones P; Ray WJ
    Int J Mol Sci; 2020 Jul; 21(14):. PubMed ID: 32659913
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeted disruption of dual leucine zipper kinase and leucine zipper kinase promotes neuronal survival in a model of diffuse traumatic brain injury.
    Welsbie DS; Ziogas NK; Xu L; Kim BJ; Ge Y; Patel AK; Ryu J; Lehar M; Alexandris AS; Stewart N; Zack DJ; Koliatsos VE
    Mol Neurodegener; 2019 Nov; 14(1):44. PubMed ID: 31775817
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fragile axons forge the path to gene discovery: a MAP kinase pathway regulates axon regeneration.
    O'Brien GS; Sagasti A
    Sci Signal; 2009 May; 2(69):pe30. PubMed ID: 19417215
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease.
    Le Pichon CE; Meilandt WJ; Dominguez S; Solanoy H; Lin H; Ngu H; Gogineni A; Sengupta Ghosh A; Jiang Z; Lee SH; Maloney J; Gandham VD; Pozniak CD; Wang B; Lee S; Siu M; Patel S; Modrusan Z; Liu X; Rudhard Y; Baca M; Gustafson A; Kaminker J; Carano RAD; Huang EJ; Foreman O; Weimer R; Scearce-Levie K; Lewcock JW
    Sci Transl Med; 2017 Aug; 9(403):. PubMed ID: 28814543
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12) with Activity in a Model of Alzheimer's Disease.
    Patel S; Meilandt WJ; Erickson RI; Chen J; Deshmukh G; Estrada AA; Fuji RN; Gibbons P; Gustafson A; Harris SF; Imperio J; Liu W; Liu X; Liu Y; Lyssikatos JP; Ma C; Yin J; Lewcock JW; Siu M
    J Med Chem; 2017 Oct; 60(19):8083-8102. PubMed ID: 28929759
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dual leucine zipper kinase as a therapeutic target for neurodegenerative conditions.
    Ferraris D; Yang Z; Welsbie D
    Future Med Chem; 2013 Oct; 5(16):1923-34. PubMed ID: 24175744
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FK506-binding protein-like and FK506-binding protein 8 regulate dual leucine zipper kinase degradation and neuronal responses to axon injury.
    Lee B; Oh Y; Cho E; DiAntonio A; Cavalli V; Shin JE; Choi HW; Cho Y
    J Biol Chem; 2022 Mar; 298(3):101647. PubMed ID: 35101451
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multitasking: Dual Leucine Zipper-Bearing Kinases in Neuronal Development and Stress Management.
    Jin Y; Zheng B
    Annu Rev Cell Dev Biol; 2019 Oct; 35():501-521. PubMed ID: 31590586
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DLK: the "preconditioning" signal for axon regeneration?
    Nix P; Bastiani M
    Neuron; 2012 Jun; 74(6):961-3. PubMed ID: 22726825
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Distinct functions of the dual leucine zipper kinase depending on its subcellular localization.
    Wallbach M; Duque Escobar J; Babaeikelishomi R; Stahnke MJ; Blume R; Schröder S; Kruegel J; Maedler K; Kluth O; Kehlenbach RH; Miosge N; Oetjen E
    Cell Signal; 2016 Apr; 28(4):272-83. PubMed ID: 26776303
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DLK regulates a distinctive transcriptional regeneration program after peripheral nerve injury.
    Shin JE; Ha H; Kim YK; Cho Y; DiAntonio A
    Neurobiol Dis; 2019 Jul; 127():178-192. PubMed ID: 30735704
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.