These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. The immunogenicity of antibody aggregates in a novel transgenic mouse model. Bessa J; Boeckle S; Beck H; Buckel T; Schlicht S; Ebeling M; Kiialainen A; Koulov A; Boll B; Weiser T; Singer T; Rolink AG; Iglesias A Pharm Res; 2015 Jul; 32(7):2344-59. PubMed ID: 25630815 [TBL] [Abstract][Full Text] [Related]
4. Investigation of the immunogenicity of different types of aggregates of a murine monoclonal antibody in mice. Freitag AJ; Shomali M; Michalakis S; Biel M; Siedler M; Kaymakcalan Z; Carpenter JF; Randolph TW; Winter G; Engert J Pharm Res; 2015 Feb; 32(2):430-44. PubMed ID: 25123991 [TBL] [Abstract][Full Text] [Related]
5. The immunogenicity of an anti-EGFR single domain antibody (V Kibria MG; Akazawa-Ogawa Y; Rahman N; Hagihara Y; Kuroda Y Eur J Pharm Biopharm; 2020 Jul; 152():164-174. PubMed ID: 32416134 [TBL] [Abstract][Full Text] [Related]
6. Immunogenicity of protein aggregates of a monoclonal antibody generated by forced shaking stress with siliconized and nonsiliconized syringes in BALB/c mice. Uchino T; Miyazaki Y; Yamazaki T; Kagawa Y J Pharm Pharmacol; 2017 Oct; 69(10):1341-1351. PubMed ID: 28639328 [TBL] [Abstract][Full Text] [Related]
8. Managing unwanted immunogenicity of biologicals. Deehan M; Garcês S; Kramer D; Baker MP; Rat D; Roettger Y; Kromminga A Autoimmun Rev; 2015 Jul; 14(7):569-74. PubMed ID: 25742758 [TBL] [Abstract][Full Text] [Related]
9. Evaluation of a 3D Human Artificial Lymph Node as Test Model for the Assessment of Immunogenicity of Protein Aggregates. Kraus T; Lubitz A; Schließer U; Giese C; Reuschel J; Brecht R; Engert J; Winter G J Pharm Sci; 2019 Jul; 108(7):2358-2366. PubMed ID: 30797781 [TBL] [Abstract][Full Text] [Related]
10. A novel mouse strain optimized for chronic human antibody administration. Gupta A; Smith P; Bournazos S; Ravetch JV Proc Natl Acad Sci U S A; 2022 Mar; 119(10):e2123002119. PubMed ID: 35235456 [TBL] [Abstract][Full Text] [Related]
11. Submicron Size Particles of a Murine Monoclonal Antibody Are More Immunogenic Than Soluble Oligomers or Micron Size Particles Upon Subcutaneous Administration in Mice. Kijanka G; Bee JS; Korman SA; Wu Y; Roskos LK; Schenerman MA; Slütter B; Jiskoot W J Pharm Sci; 2018 Nov; 107(11):2847-2859. PubMed ID: 30003898 [TBL] [Abstract][Full Text] [Related]
12. Generation and characterization of dimeric small immunoproteins specific for neuroblastoma associated antigen GD2. Occhino M; Raffaghello L; Burrone O; Gambini C; Pistoia V; Corrias MV; Bestagno M Int J Mol Med; 2004 Sep; 14(3):383-8. PubMed ID: 15289889 [TBL] [Abstract][Full Text] [Related]
13. Immunogenicity of different stressed IgG monoclonal antibody formulations in immune tolerant transgenic mice. Filipe V; Jiskoot W; Basmeleh AH; Halim A; Schellekens H; Brinks V MAbs; 2012; 4(6):740-52. PubMed ID: 22951518 [TBL] [Abstract][Full Text] [Related]
14. Test models for the evaluation of immunogenicity of protein aggregates. Kraus T; Winter G; Engert J Int J Pharm; 2019 Mar; 559():192-200. PubMed ID: 30665000 [TBL] [Abstract][Full Text] [Related]
15. Extensive Chemical Modifications in the Primary Protein Structure of IgG1 Subvisible Particles Are Necessary for Breaking Immune Tolerance. Boll B; Bessa J; Folzer E; Ríos Quiroz A; Schmidt R; Bulau P; Finkler C; Mahler HC; Huwyler J; Iglesias A; Koulov AV Mol Pharm; 2017 Apr; 14(4):1292-1299. PubMed ID: 28206769 [TBL] [Abstract][Full Text] [Related]
16. In Vivo Effect of Innate Immune Response Modulating Impurities on the Skin Milieu Using a Macaque Model: Impact on Product Immunogenicity. Haile LA; Puig M; Polumuri SK; Ascher J; Verthelyi D J Pharm Sci; 2017 Mar; 106(3):751-760. PubMed ID: 27923493 [TBL] [Abstract][Full Text] [Related]
17. Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies. Rane SS; Dearman RJ; Kimber I; Uddin S; Bishop S; Shah M; Podmore A; Pluen A; Derrick JP Pharm Res; 2019 Feb; 36(4):51. PubMed ID: 30771015 [TBL] [Abstract][Full Text] [Related]
18. Development of a human antibody tolerant mouse model to assess the immunogenicity risk due to aggregated biotherapeutics. Bi V; Jawa V; Joubert MK; Kaliyaperumal A; Eakin C; Richmond K; Pan O; Sun J; Hokom M; Goletz TJ; Wypych J; Zhou L; Kerwin BA; Narhi LO; Arora T J Pharm Sci; 2013 Oct; 102(10):3545-55. PubMed ID: 23925953 [TBL] [Abstract][Full Text] [Related]
19. Assessment of the immunogenicity of mechanically induced interferon aggregates in a transgenic mouse model. Human P; Ilsley H; Roberson C; Grovender E; Van Antwerp B; Fogt E; Zilla P J Pharm Sci; 2015 Feb; 104(2):722-30. PubMed ID: 25450064 [TBL] [Abstract][Full Text] [Related]
20. Immunogenicity of Structurally Perturbed Hen Egg Lysozyme Adsorbed to Silicone Oil Microdroplets in Wild-Type and Transgenic Mouse Models. Chisholm CF; Soucie KR; Song JS; Strauch P; Torres RM; Carpenter JF; Ragheb JA; Randolph TW J Pharm Sci; 2017 Jun; 106(6):1519-1527. PubMed ID: 28216023 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]