BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

497 related articles for article (PubMed ID: 27048880)

  • 21. Children are not just little adults: recent advances in understanding of diffuse intrinsic pontine glioma biology.
    Schroeder KM; Hoeman CM; Becher OJ
    Pediatr Res; 2014 Jan; 75(1-2):205-9. PubMed ID: 24192697
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics.
    Hoffman LM; DeWire M; Ryall S; Buczkowicz P; Leach J; Miles L; Ramani A; Brudno M; Kumar SS; Drissi R; Dexheimer P; Salloum R; Chow L; Hummel T; Stevenson C; Lu QR; Jones B; Witte D; Aronow B; Hawkins CE; Fouladi M
    Acta Neuropathol Commun; 2016 Jan; 4():1. PubMed ID: 26727948
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Histone H3.3K27M Represses
    Cordero FJ; Huang Z; Grenier C; He X; Hu G; McLendon RE; Murphy SK; Hashizume R; Becher OJ
    Mol Cancer Res; 2017 Sep; 15(9):1243-1254. PubMed ID: 28522693
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Diffuse Midline Gliomas with Histone H3-K27M Mutation: A Series of 47 Cases Assessing the Spectrum of Morphologic Variation and Associated Genetic Alterations.
    Solomon DA; Wood MD; Tihan T; Bollen AW; Gupta N; Phillips JJ; Perry A
    Brain Pathol; 2016 Sep; 26(5):569-80. PubMed ID: 26517431
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Identification of Novel RAS Signaling Therapeutic Vulnerabilities in Diffuse Intrinsic Pontine Gliomas.
    Koncar RF; Dey BR; Stanton AJ; Agrawal N; Wassell ML; McCarl LH; Locke AL; Sanders L; Morozova-Vaske O; Myers MI; Hamilton RL; Carcaboso AM; Kohanbash G; Hu B; Amankulor NM; Felker J; Kambhampati M; Nazarian J; Becher OJ; James CD; Hashizume R; Broniscer A; Pollack IF; Agnihotri S
    Cancer Res; 2019 Aug; 79(16):4026-4041. PubMed ID: 31201162
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations.
    Buczkowicz P; Hoeman C; Rakopoulos P; Pajovic S; Letourneau L; Dzamba M; Morrison A; Lewis P; Bouffet E; Bartels U; Zuccaro J; Agnihotri S; Ryall S; Barszczyk M; Chornenkyy Y; Bourgey M; Bourque G; Montpetit A; Cordero F; Castelo-Branco P; Mangerel J; Tabori U; Ho KC; Huang A; Taylor KR; Mackay A; Bendel AE; Nazarian J; Fangusaro JR; Karajannis MA; Zagzag D; Foreman NK; Donson A; Hegert JV; Smith A; Chan J; Lafay-Cousin L; Dunn S; Hukin J; Dunham C; Scheinemann K; Michaud J; Zelcer S; Ramsay D; Cain J; Brennan C; Souweidane MM; Jones C; Allis CD; Brudno M; Becher O; Hawkins C
    Nat Genet; 2014 May; 46(5):451-6. PubMed ID: 24705254
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Targeting Mutant PPM1D Sensitizes Diffuse Intrinsic Pontine Glioma Cells to the PARP Inhibitor Olaparib.
    Wang Z; Xu C; Diplas BH; Moure CJ; Chen CJ; Chen LH; Du C; Zhu H; Greer PK; Zhang L; He Y; Waitkus MS; Yan H
    Mol Cancer Res; 2020 Jul; 18(7):968-980. PubMed ID: 32229503
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Medulloblastoma therapy generates risk of a poorly-prognostic H3 wild-type subgroup of diffuse intrinsic pontine glioma: a report from the International DIPG Registry.
    Gits HC; Anderson M; Stallard S; Pratt D; Zon B; Howell C; Kumar-Sinha C; Vats P; Kasaian K; Polan D; Matuszak M; Spratt DE; Leonard M; Qin T; Zhao L; Leach J; Chaney B; Escorza NY; Hendershot J; Jones B; Fuller C; Leary S; Bartels U; Bouffet E; Yock TI; Robertson P; Mody R; Venneti S; Chinnaiyan AM; Fouladi M; Gottardo NG; Koschmann C
    Acta Neuropathol Commun; 2018 Jul; 6(1):67. PubMed ID: 30049282
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas.
    Zhang L; Chen LH; Wan H; Yang R; Wang Z; Feng J; Yang S; Jones S; Wang S; Zhou W; Zhu H; Killela PJ; Zhang J; Wu Z; Li G; Hao S; Wang Y; Webb JB; Friedman HS; Friedman AH; McLendon RE; He Y; Reitman ZJ; Bigner DD; Yan H
    Nat Genet; 2014 Jul; 46(7):726-30. PubMed ID: 24880341
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas.
    Fortin J; Tian R; Zarrabi I; Hill G; Williams E; Sanchez-Duffhues G; Thorikay M; Ramachandran P; Siddaway R; Wong JF; Wu A; Apuzzo LN; Haight J; You-Ten A; Snow BE; Wakeham A; Goldhamer DJ; Schramek D; Bullock AN; Dijke PT; Hawkins C; Mak TW
    Cancer Cell; 2020 Mar; 37(3):308-323.e12. PubMed ID: 32142668
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The H3K27M mutation alters stem cell growth, epigenetic regulation, and differentiation potential.
    Kfoury-Beaumont N; Prakasam R; Pondugula S; Lagas JS; Matkovich S; Gontarz P; Yang L; Yano H; Kim AH; Rubin JB; Kroll KL
    BMC Biol; 2022 May; 20(1):124. PubMed ID: 35637482
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Inhibition of mutant PPM1D enhances DNA damage response and growth suppressive effects of ionizing radiation in diffuse intrinsic pontine glioma.
    Akamandisa MP; Nie K; Nahta R; Hambardzumyan D; Castellino RC
    Neuro Oncol; 2019 Jun; 21(6):786-799. PubMed ID: 30852603
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Histone H3.3 K27M chromatin functions implicate a network of neurodevelopmental factors including ASCL1 and NEUROD1 in DIPG.
    Lewis NA; Klein RH; Kelly C; Yee J; Knoepfler PS
    Epigenetics Chromatin; 2022 May; 15(1):18. PubMed ID: 35590427
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma.
    Nagaraja S; Vitanza NA; Woo PJ; Taylor KR; Liu F; Zhang L; Li M; Meng W; Ponnuswami A; Sun W; Ma J; Hulleman E; Swigut T; Wysocka J; Tang Y; Monje M
    Cancer Cell; 2017 May; 31(5):635-652.e6. PubMed ID: 28434841
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Diffuse intrinsic pontine gliomas-current management and new biologic insights. Is there a glimmer of hope?
    Cohen KJ; Jabado N; Grill J
    Neuro Oncol; 2017 Aug; 19(8):1025-1034. PubMed ID: 28371920
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Global activation of oncogenic pathways underlies therapy resistance in diffuse midline glioma.
    Georgescu MM; Islam MZ; Li Y; Circu ML; Traylor J; Notarianni CM; Kline CN; Burns DK
    Acta Neuropathol Commun; 2020 Jul; 8(1):111. PubMed ID: 32680567
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma.
    Wu G; Diaz AK; Paugh BS; Rankin SL; Ju B; Li Y; Zhu X; Qu C; Chen X; Zhang J; Easton J; Edmonson M; Ma X; Lu C; Nagahawatte P; Hedlund E; Rusch M; Pounds S; Lin T; Onar-Thomas A; Huether R; Kriwacki R; Parker M; Gupta P; Becksfort J; Wei L; Mulder HL; Boggs K; Vadodaria B; Yergeau D; Russell JC; Ochoa K; Fulton RS; Fulton LL; Jones C; Boop FA; Broniscer A; Wetmore C; Gajjar A; Ding L; Mardis ER; Wilson RK; Taylor MR; Downing JR; Ellison DW; Zhang J; Baker SJ
    Nat Genet; 2014 May; 46(5):444-450. PubMed ID: 24705251
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas.
    Piunti A; Hashizume R; Morgan MA; Bartom ET; Horbinski CM; Marshall SA; Rendleman EJ; Ma Q; Takahashi YH; Woodfin AR; Misharin AV; Abshiru NA; Lulla RR; Saratsis AM; Kelleher NL; James CD; Shilatifard A
    Nat Med; 2017 Apr; 23(4):493-500. PubMed ID: 28263307
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The Long Non-Coding RNA H19 Drives the Proliferation of Diffuse Intrinsic Pontine Glioma with H3K27 Mutation.
    Roig-Carles D; Jackson H; Loveson KF; Mackay A; Mather RL; Waters E; Manzo M; Alborelli I; Golding J; Jones C; Fillmore HL; Crea F
    Int J Mol Sci; 2021 Aug; 22(17):. PubMed ID: 34502082
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Epigenetic-Targeted Treatments for H3K27M-Mutant Midline Gliomas.
    Lu VM; Daniels DJ
    Adv Exp Med Biol; 2021; 1283():73-84. PubMed ID: 33155139
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 25.