267 related articles for article (PubMed ID: 27050460)
1. TARDBP/TDP-43 regulates autophagy in both MTORC1-dependent and MTORC1-independent manners.
Ying Z; Xia Q; Hao Z; Xu D; Wang M; Wang H; Wang G
Autophagy; 2016; 12(4):707-8. PubMed ID: 27050460
[TBL] [Abstract][Full Text] [Related]
2. TDP-43 loss of function increases TFEB activity and blocks autophagosome-lysosome fusion.
Xia Q; Wang H; Hao Z; Fu C; Hu Q; Gao F; Ren H; Chen D; Han J; Ying Z; Wang G
EMBO J; 2016 Jan; 35(2):121-42. PubMed ID: 26702100
[TBL] [Abstract][Full Text] [Related]
3. Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion.
Zhou J; Tan SH; Nicolas V; Bauvy C; Yang ND; Zhang J; Xue Y; Codogno P; Shen HM
Cell Res; 2013 Apr; 23(4):508-23. PubMed ID: 23337583
[TBL] [Abstract][Full Text] [Related]
4. Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner.
Newton PT; Vuppalapati KK; Bouderlique T; Chagin AS
Autophagy; 2015; 11(9):1594-607. PubMed ID: 26259639
[TBL] [Abstract][Full Text] [Related]
5. The lysosome: a crucial hub for AMPK and mTORC1 signalling.
Carroll B; Dunlop EA
Biochem J; 2017 Apr; 474(9):1453-1466. PubMed ID: 28408430
[TBL] [Abstract][Full Text] [Related]
6. Dual suppressive effect of MTORC1 on autophagy: tame the dragon by shackling both the head and the tail.
Zhou J; Tan SH; Codogno P; Shen HM
Autophagy; 2013 May; 9(5):803-5. PubMed ID: 23439250
[TBL] [Abstract][Full Text] [Related]
7. Suppression of lysosome function induces autophagy via a feedback down-regulation of MTOR complex 1 (MTORC1) activity.
Li M; Khambu B; Zhang H; Kang JH; Chen X; Chen D; Vollmer L; Liu PQ; Vogt A; Yin XM
J Biol Chem; 2013 Dec; 288(50):35769-80. PubMed ID: 24174532
[TBL] [Abstract][Full Text] [Related]
8. Drosophila Mitf regulates the V-ATPase and the lysosomal-autophagic pathway.
Bouché V; Espinosa AP; Leone L; Sardiello M; Ballabio A; Botas J
Autophagy; 2016; 12(3):484-98. PubMed ID: 26761346
[TBL] [Abstract][Full Text] [Related]
9. Combined regulation of mTORC1 and lysosomal acidification by GSK-3 suppresses autophagy and contributes to cancer cell growth.
Azoulay-Alfaguter I; Elya R; Avrahami L; Katz A; Eldar-Finkelman H
Oncogene; 2015 Aug; 34(35):4613-23. PubMed ID: 25500539
[TBL] [Abstract][Full Text] [Related]
10. At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy.
Shen HM; Mizushima N
Trends Biochem Sci; 2014 Feb; 39(2):61-71. PubMed ID: 24369758
[TBL] [Abstract][Full Text] [Related]
11. Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling.
Valapala M; Wilson C; Hose S; Bhutto IA; Grebe R; Dong A; Greenbaum S; Gu L; Sengupta S; Cano M; Hackett S; Xu G; Lutty GA; Dong L; Sergeev Y; Handa JT; Campochiaro P; Wawrousek E; Zigler JS; Sinha D
Autophagy; 2014 Mar; 10(3):480-96. PubMed ID: 24468901
[TBL] [Abstract][Full Text] [Related]
12. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy.
Ruf S; Heberle AM; Langelaar-Makkinje M; Gelino S; Wilkinson D; Gerbeth C; Schwarz JJ; Holzwarth B; Warscheid B; Meisinger C; van Vugt MA; Baumeister R; Hansen M; Thedieck K
Autophagy; 2017 Mar; 13(3):486-505. PubMed ID: 28102733
[TBL] [Abstract][Full Text] [Related]
13. The amino acid transporter SLC38A9 regulates MTORC1 and autophagy.
Jin M; Klionsky DJ
Autophagy; 2015; 11(10):1709-10. PubMed ID: 26506891
[TBL] [Abstract][Full Text] [Related]
14. Autophagy modulates amino acid signaling network in myotubes: differential effects on mTORC1 pathway and the integrated stress response.
Yu X; Long YC
FASEB J; 2015 Feb; 29(2):394-407. PubMed ID: 25376834
[TBL] [Abstract][Full Text] [Related]
15. A cell-penetrating ester of the neural metabolite lanthionine ketimine stimulates autophagy through the mTORC1 pathway: Evidence for a mechanism of action with pharmacological implications for neurodegenerative pathologies.
Harris-White ME; Ferbas KG; Johnson MF; Eslami P; Poteshkina A; Venkova K; Christov A; Hensley K
Neurobiol Dis; 2015 Dec; 84():60-8. PubMed ID: 25779968
[TBL] [Abstract][Full Text] [Related]
16. p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb.
Agarwal S; Bell CM; Taylor SM; Moran RG
Mol Cancer Res; 2016 Jan; 14(1):66-77. PubMed ID: 26385560
[TBL] [Abstract][Full Text] [Related]
17. Increased lysosomal biogenesis in activated microglia and exacerbated neuronal damage after traumatic brain injury in progranulin-deficient mice.
Tanaka Y; Matsuwaki T; Yamanouchi K; Nishihara M
Neuroscience; 2013 Oct; 250():8-19. PubMed ID: 23830905
[TBL] [Abstract][Full Text] [Related]
18. Cucurbitacin E Induces Autophagy via Downregulating mTORC1 Signaling and Upregulating AMPK Activity.
Zha QB; Zhang XY; Lin QR; Xu LH; Zhao GX; Pan H; Zhou D; Ouyang DY; Liu ZH; He XH
PLoS One; 2015; 10(5):e0124355. PubMed ID: 25970614
[TBL] [Abstract][Full Text] [Related]
19. Electroacupuncture protects against ischemic stroke by reducing autophagosome formation and inhibiting autophagy through the mTORC1-ULK1 complex-Beclin1 pathway.
Liu W; Shang G; Yang S; Huang J; Xue X; Lin Y; Zheng Y; Wang X; Wang L; Lin R; Tao J; Chen L
Int J Mol Med; 2016 Feb; 37(2):309-18. PubMed ID: 26647915
[TBL] [Abstract][Full Text] [Related]
20. PDMP, a ceramide analogue, acts as an inhibitor of mTORC1 by inducing its translocation from lysosome to endoplasmic reticulum.
Ode T; Podyma-Inoue KA; Terasawa K; Inokuchi JI; Kobayashi T; Watabe T; Izumi Y; Hara-Yokoyama M
Exp Cell Res; 2017 Jan; 350(1):103-114. PubMed ID: 27865938
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]