BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

267 related articles for article (PubMed ID: 27050460)

  • 1. TARDBP/TDP-43 regulates autophagy in both MTORC1-dependent and MTORC1-independent manners.
    Ying Z; Xia Q; Hao Z; Xu D; Wang M; Wang H; Wang G
    Autophagy; 2016; 12(4):707-8. PubMed ID: 27050460
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TDP-43 loss of function increases TFEB activity and blocks autophagosome-lysosome fusion.
    Xia Q; Wang H; Hao Z; Fu C; Hu Q; Gao F; Ren H; Chen D; Han J; Ying Z; Wang G
    EMBO J; 2016 Jan; 35(2):121-42. PubMed ID: 26702100
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion.
    Zhou J; Tan SH; Nicolas V; Bauvy C; Yang ND; Zhang J; Xue Y; Codogno P; Shen HM
    Cell Res; 2013 Apr; 23(4):508-23. PubMed ID: 23337583
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner.
    Newton PT; Vuppalapati KK; Bouderlique T; Chagin AS
    Autophagy; 2015; 11(9):1594-607. PubMed ID: 26259639
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The lysosome: a crucial hub for AMPK and mTORC1 signalling.
    Carroll B; Dunlop EA
    Biochem J; 2017 Apr; 474(9):1453-1466. PubMed ID: 28408430
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dual suppressive effect of MTORC1 on autophagy: tame the dragon by shackling both the head and the tail.
    Zhou J; Tan SH; Codogno P; Shen HM
    Autophagy; 2013 May; 9(5):803-5. PubMed ID: 23439250
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Suppression of lysosome function induces autophagy via a feedback down-regulation of MTOR complex 1 (MTORC1) activity.
    Li M; Khambu B; Zhang H; Kang JH; Chen X; Chen D; Vollmer L; Liu PQ; Vogt A; Yin XM
    J Biol Chem; 2013 Dec; 288(50):35769-80. PubMed ID: 24174532
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Drosophila Mitf regulates the V-ATPase and the lysosomal-autophagic pathway.
    Bouché V; Espinosa AP; Leone L; Sardiello M; Ballabio A; Botas J
    Autophagy; 2016; 12(3):484-98. PubMed ID: 26761346
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combined regulation of mTORC1 and lysosomal acidification by GSK-3 suppresses autophagy and contributes to cancer cell growth.
    Azoulay-Alfaguter I; Elya R; Avrahami L; Katz A; Eldar-Finkelman H
    Oncogene; 2015 Aug; 34(35):4613-23. PubMed ID: 25500539
    [TBL] [Abstract][Full Text] [Related]  

  • 10. At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy.
    Shen HM; Mizushima N
    Trends Biochem Sci; 2014 Feb; 39(2):61-71. PubMed ID: 24369758
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling.
    Valapala M; Wilson C; Hose S; Bhutto IA; Grebe R; Dong A; Greenbaum S; Gu L; Sengupta S; Cano M; Hackett S; Xu G; Lutty GA; Dong L; Sergeev Y; Handa JT; Campochiaro P; Wawrousek E; Zigler JS; Sinha D
    Autophagy; 2014 Mar; 10(3):480-96. PubMed ID: 24468901
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy.
    Ruf S; Heberle AM; Langelaar-Makkinje M; Gelino S; Wilkinson D; Gerbeth C; Schwarz JJ; Holzwarth B; Warscheid B; Meisinger C; van Vugt MA; Baumeister R; Hansen M; Thedieck K
    Autophagy; 2017 Mar; 13(3):486-505. PubMed ID: 28102733
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The amino acid transporter SLC38A9 regulates MTORC1 and autophagy.
    Jin M; Klionsky DJ
    Autophagy; 2015; 11(10):1709-10. PubMed ID: 26506891
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Autophagy modulates amino acid signaling network in myotubes: differential effects on mTORC1 pathway and the integrated stress response.
    Yu X; Long YC
    FASEB J; 2015 Feb; 29(2):394-407. PubMed ID: 25376834
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A cell-penetrating ester of the neural metabolite lanthionine ketimine stimulates autophagy through the mTORC1 pathway: Evidence for a mechanism of action with pharmacological implications for neurodegenerative pathologies.
    Harris-White ME; Ferbas KG; Johnson MF; Eslami P; Poteshkina A; Venkova K; Christov A; Hensley K
    Neurobiol Dis; 2015 Dec; 84():60-8. PubMed ID: 25779968
    [TBL] [Abstract][Full Text] [Related]  

  • 16. p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb.
    Agarwal S; Bell CM; Taylor SM; Moran RG
    Mol Cancer Res; 2016 Jan; 14(1):66-77. PubMed ID: 26385560
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Increased lysosomal biogenesis in activated microglia and exacerbated neuronal damage after traumatic brain injury in progranulin-deficient mice.
    Tanaka Y; Matsuwaki T; Yamanouchi K; Nishihara M
    Neuroscience; 2013 Oct; 250():8-19. PubMed ID: 23830905
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cucurbitacin E Induces Autophagy via Downregulating mTORC1 Signaling and Upregulating AMPK Activity.
    Zha QB; Zhang XY; Lin QR; Xu LH; Zhao GX; Pan H; Zhou D; Ouyang DY; Liu ZH; He XH
    PLoS One; 2015; 10(5):e0124355. PubMed ID: 25970614
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Electroacupuncture protects against ischemic stroke by reducing autophagosome formation and inhibiting autophagy through the mTORC1-ULK1 complex-Beclin1 pathway.
    Liu W; Shang G; Yang S; Huang J; Xue X; Lin Y; Zheng Y; Wang X; Wang L; Lin R; Tao J; Chen L
    Int J Mol Med; 2016 Feb; 37(2):309-18. PubMed ID: 26647915
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PDMP, a ceramide analogue, acts as an inhibitor of mTORC1 by inducing its translocation from lysosome to endoplasmic reticulum.
    Ode T; Podyma-Inoue KA; Terasawa K; Inokuchi JI; Kobayashi T; Watabe T; Izumi Y; Hara-Yokoyama M
    Exp Cell Res; 2017 Jan; 350(1):103-114. PubMed ID: 27865938
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.