BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 27052176)

  • 1. p53 Maintains Genomic Stability by Preventing Interference between Transcription and Replication.
    Yeo CQX; Alexander I; Lin Z; Lim S; Aning OA; Kumar R; Sangthongpitag K; Pendharkar V; Ho VHB; Cheok CF
    Cell Rep; 2016 Apr; 15(1):132-146. PubMed ID: 27052176
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ZATT-TOP2A-PICH Axis Drives Extensive Replication Fork Reversal to Promote Genome Stability.
    Tian T; Bu M; Chen X; Ding L; Yang Y; Han J; Feng XH; Xu P; Liu T; Ying S; Lei Y; Li Q; Huang J
    Mol Cell; 2021 Jan; 81(1):198-211.e6. PubMed ID: 33296677
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The catalytic topoisomerase II inhibitor dexrazoxane induces DNA breaks, ATF3 and the DNA damage response in cancer cells.
    Deng S; Yan T; Nikolova T; Fuhrmann D; Nemecek A; Gödtel-Armbrust U; Kaina B; Wojnowski L
    Br J Pharmacol; 2015 May; 172(9):2246-57. PubMed ID: 25521189
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p53 dependence of topoisomerase I recruitment in vivo.
    Mao Y; Okada S; Chang LS; Muller MT
    Cancer Res; 2000 Aug; 60(16):4538-43. PubMed ID: 10969804
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cellular processing pathways contribute to the activation of etoposide-induced DNA damage responses.
    Fan JR; Peng AL; Chen HC; Lo SC; Huang TH; Li TK
    DNA Repair (Amst); 2008 Mar; 7(3):452-63. PubMed ID: 18206427
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Topoisomerase IIalpha mediates E2F-1-induced chemosensitivity and is a target for p53-mediated transcriptional repression.
    Nip J; Hiebert SW
    Cell Biochem Biophys; 2000; 33(2):199-207. PubMed ID: 11325040
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA damage response (DDR) induced by topoisomerase II poisons requires nuclear function of the small GTPase Rac.
    Wartlick F; Bopp A; Henninger C; Fritz G
    Biochim Biophys Acta; 2013 Dec; 1833(12):3093-3103. PubMed ID: 23999236
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of DNA topoisomerase II alpha gene expression by the p53 tumor suppressor.
    Wang Q; Zambetti GP; Suttle DP
    Mol Cell Biol; 1997 Jan; 17(1):389-97. PubMed ID: 8972219
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nuclear factor-Y binding to the topoisomerase IIalpha promoter is inhibited by both the p53 tumor suppressor and anticancer drugs.
    Joshi AA; Wu Z; Reed RF; Suttle DP
    Mol Pharmacol; 2003 Feb; 63(2):359-67. PubMed ID: 12527807
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Down-regulation of nuclear protein ICBP90 by p53/p21Cip1/WAF1-dependent DNA-damage checkpoint signals contributes to cell cycle arrest at G1/S transition.
    Arima Y; Hirota T; Bronner C; Mousli M; Fujiwara T; Niwa S; Ishikawa H; Saya H
    Genes Cells; 2004 Feb; 9(2):131-42. PubMed ID: 15009091
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The dual-acting chemotherapeutic agent Alchemix induces cell death independently of ATM and p53.
    Thomas A; Perry T; Berhane S; Oldreive C; Zlatanou A; Williams LR; Weston VJ; Stankovic T; Kearns P; Pors K; Grand RJ; Stewart GS
    Oncogene; 2015 Jun; 34(25):3336-48. PubMed ID: 25132271
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutual regulation of MDM4 and TOP2A in cancer cell proliferation.
    Liu T; Zhang H; Yi S; Gu L; Zhou M
    Mol Oncol; 2019 May; 13(5):1047-1058. PubMed ID: 30672125
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Human topoisomerase IIalpha and IIbeta interact with the C-terminal region of p53.
    Cowell IG; Okorokov AL; Cutts SA; Padget K; Bell M; Milner J; Austin CA
    Exp Cell Res; 2000 Feb; 255(1):86-94. PubMed ID: 10666337
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Topoisomerase II{alpha}-dependent and -independent apoptotic effects of dexrazoxane and doxorubicin.
    Yan T; Deng S; Metzger A; Gödtel-Armbrust U; Porter AC; Wojnowski L
    Mol Cancer Ther; 2009 May; 8(5):1075-85. PubMed ID: 19417146
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The p53 tumor suppressor stimulates the catalytic activity of human topoisomerase IIalpha by enhancing the rate of ATP hydrolysis.
    Kwon Y; Shin BS; Chung IK
    J Biol Chem; 2000 Jun; 275(24):18503-10. PubMed ID: 10764786
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High speed of fork progression induces DNA replication stress and genomic instability.
    Maya-Mendoza A; Moudry P; Merchut-Maya JM; Lee M; Strauss R; Bartek J
    Nature; 2018 Jul; 559(7713):279-284. PubMed ID: 29950726
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overexpression of Topoisomerase 2-Alpha Confers a Poor Prognosis in Pancreatic Adenocarcinoma Identified by Co-Expression Analysis.
    Zhou Z; Liu S; Zhang M; Zhou R; Liu J; Chang Y; Zhao Q
    Dig Dis Sci; 2017 Oct; 62(10):2790-2800. PubMed ID: 28815403
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cryptolepine, a Plant Alkaloid, Inhibits the Growth of Non-Melanoma Skin Cancer Cells through Inhibition of Topoisomerase and Induction of DNA Damage.
    Pal HC; Katiyar SK
    Molecules; 2016 Dec; 21(12):. PubMed ID: 28009843
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Topoisomerase IIα prevents ultrafine anaphase bridges by two mechanisms.
    Gemble S; Buhagiar-Labarchède G; Onclercq-Delic R; Fontaine G; Lambert S; Amor-Guéret M
    Open Biol; 2020 May; 10(5):190259. PubMed ID: 32400307
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers.
    Sønderstrup IM; Nygård SB; Poulsen TS; Linnemann D; Stenvang J; Nielsen HJ; Bartek J; Brünner N; Nørgaard P; Riis L
    Mol Oncol; 2015 Jun; 9(6):1207-17. PubMed ID: 25777966
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.