BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

396 related articles for article (PubMed ID: 27055402)

  • 1. Cooperative antiproliferative signaling by aspirin and indole-3-carbinol targets microphthalmia-associated transcription factor gene expression and promoter activity in human melanoma cells.
    Poindexter KM; Matthew S; Aronchik I; Firestone GL
    Cell Biol Toxicol; 2016 Apr; 32(2):103-19. PubMed ID: 27055402
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 1-Benzyl-indole-3-carbinol is a highly potent new small molecule inhibitor of Wnt/β-catenin signaling in melanoma cells that coordinately inhibits cell proliferation and disrupts expression of microphthalmia-associated transcription factor isoform-M.
    Kundu A; Khouri MG; Aryana S; Firestone GL
    Carcinogenesis; 2017 Dec; 38(12):1207-1217. PubMed ID: 29028954
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of oncogenic BRAF activity by indole-3-carbinol disrupts microphthalmia-associated transcription factor expression and arrests melanoma cell proliferation.
    Kundu A; Quirit JG; Khouri MG; Firestone GL
    Mol Carcinog; 2017 Jan; 56(1):49-61. PubMed ID: 26878440
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Indole-3-carbinol and ultraviolet B induce apoptosis of human melanoma cells via down-regulation of MITF.
    Kim SY; Kima DS; Jeong YM; Moon SI; Kwon SB; Park KC
    Pharmazie; 2011 Dec; 66(12):982-7. PubMed ID: 22312706
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The antiproliferative response of indole-3-carbinol in human melanoma cells is triggered by an interaction with NEDD4-1 and disruption of wild-type PTEN degradation.
    Aronchik I; Kundu A; Quirit JG; Firestone GL
    Mol Cancer Res; 2014 Nov; 12(11):1621-1634. PubMed ID: 25009292
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Indole-3-carbinol and 3-3'-diindolylmethane antiproliferative signaling pathways control cell-cycle gene transcription in human breast cancer cells by regulating promoter-Sp1 transcription factor interactions.
    Firestone GL; Bjeldanes LF
    J Nutr; 2003 Jul; 133(7 Suppl):2448S-2455S. PubMed ID: 12840223
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The microphthalmia-associated transcription factor Mitf interacts with beta-catenin to determine target gene expression.
    Schepsky A; Bruser K; Gunnarsson GJ; Goodall J; Hallsson JH; Goding CR; Steingrimsson E; Hecht A
    Mol Cell Biol; 2006 Dec; 26(23):8914-27. PubMed ID: 17000761
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF.
    Wellbrock C; Rana S; Paterson H; Pickersgill H; Brummelkamp T; Marais R
    PLoS One; 2008 Jul; 3(7):e2734. PubMed ID: 18628967
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Indole-3-carbinol inhibition of androgen receptor expression and downregulation of androgen responsiveness in human prostate cancer cells.
    Hsu JC; Zhang J; Dev A; Wing A; Bjeldanes LF; Firestone GL
    Carcinogenesis; 2005 Nov; 26(11):1896-904. PubMed ID: 15958518
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Indole-3-carbinol selectively uncouples expression and activity of estrogen receptor subtypes in human breast cancer cells.
    Sundar SN; Kerekatte V; Equinozio CN; Doan VB; Bjeldanes LF; Firestone GL
    Mol Endocrinol; 2006 Dec; 20(12):3070-82. PubMed ID: 16901971
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling.
    Aronchik I; Chen T; Durkin KA; Horwitz MS; Preobrazhenskaya MN; Bjeldanes LF; Firestone GL
    Mol Carcinog; 2012 Nov; 51(11):881-94. PubMed ID: 22012859
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SWI/SNF chromatin remodeling complex is critical for the expression of microphthalmia-associated transcription factor in melanoma cells.
    Vachtenheim J; Ondrusová L; Borovanský J
    Biochem Biophys Res Commun; 2010 Feb; 392(3):454-9. PubMed ID: 20083088
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Parthenolide induces MITF-M downregulation and senescence in patient-derived MITF-M(high) melanoma cell populations.
    Hartman ML; Talar B; Sztiller-Sikorska M; Nejc D; Czyz M
    Oncotarget; 2016 Feb; 7(8):9026-40. PubMed ID: 26824319
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells.
    Quirit JG; Lavrenov SN; Poindexter K; Xu J; Kyauk C; Durkin KA; Aronchik I; Tomasiak T; Solomatin YA; Preobrazhenskaya MN; Firestone GL
    Biochem Pharmacol; 2017 Mar; 127():13-27. PubMed ID: 27979631
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of human melanoma cell growth by the dietary flavonoid fisetin is associated with disruption of Wnt/β-catenin signaling and decreased Mitf levels.
    Syed DN; Afaq F; Maddodi N; Johnson JJ; Sarfaraz S; Ahmad A; Setaluri V; Mukhtar H
    J Invest Dermatol; 2011 Jun; 131(6):1291-9. PubMed ID: 21346776
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Indole-3-carbinol mediated cell cycle arrest of LNCaP human prostate cancer cells requires the induced production of activated p53 tumor suppressor protein.
    Hsu JC; Dev A; Wing A; Brew CT; Bjeldanes LF; Firestone GL
    Biochem Pharmacol; 2006 Dec; 72(12):1714-23. PubMed ID: 16970927
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells.
    Marconett CN; Sundar SN; Tseng M; Tin AS; Tran KQ; Mahuron KM; Bjeldanes LF; Firestone GL
    Carcinogenesis; 2011 Sep; 32(9):1315-23. PubMed ID: 21693539
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GLI2 and M-MITF transcription factors control exclusive gene expression programs and inversely regulate invasion in human melanoma cells.
    Javelaud D; Alexaki VI; Pierrat MJ; Hoek KS; Dennler S; Van Kempen L; Bertolotto C; Ballotti R; Saule S; Delmas V; Mauviel A
    Pigment Cell Melanoma Res; 2011 Oct; 24(5):932-43. PubMed ID: 21801332
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BPTF transduces MITF-driven prosurvival signals in melanoma cells.
    Dar AA; Majid S; Bezrookove V; Phan B; Ursu S; Nosrati M; De Semir D; Sagebiel RW; Miller JR; Debs R; Cleaver JE; Kashani-Sabet M
    Proc Natl Acad Sci U S A; 2016 May; 113(22):6254-8. PubMed ID: 27185926
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells.
    Brew CT; Aronchik I; Hsu JC; Sheen JH; Dickson RB; Bjeldanes LF; Firestone GL
    Int J Cancer; 2006 Feb; 118(4):857-68. PubMed ID: 16152627
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.