333 related articles for article (PubMed ID: 27059953)
1. Presenilin 1 and Presenilin 2 Target γ-Secretase Complexes to Distinct Cellular Compartments.
Meckler X; Checler F
J Biol Chem; 2016 Jun; 291(24):12821-12837. PubMed ID: 27059953
[TBL] [Abstract][Full Text] [Related]
2. Specific combinations of presenilins and Aph1s affect the substrate specificity and activity of γ-secretase.
Yonemura Y; Futai E; Yagishita S; Kaether C; Ishiura S
Biochem Biophys Res Commun; 2016 Sep; 478(4):1751-7. PubMed ID: 27608597
[TBL] [Abstract][Full Text] [Related]
3. Comparison of presenilin 1 and presenilin 2 γ-secretase activities using a yeast reconstitution system.
Yonemura Y; Futai E; Yagishita S; Suo S; Tomita T; Iwatsubo T; Ishiura S
J Biol Chem; 2011 Dec; 286(52):44569-75. PubMed ID: 22074918
[TBL] [Abstract][Full Text] [Related]
4. Visualization of specific γ-secretase complexes using bimolecular fluorescence complementation.
Meckler X; Checler F
J Alzheimers Dis; 2014; 40(1):161-76. PubMed ID: 24413617
[TBL] [Abstract][Full Text] [Related]
5. Localization of presenilin-nicastrin complexes and gamma-secretase activity to the trans-Golgi network.
Siman R; Velji J
J Neurochem; 2003 Mar; 84(5):1143-53. PubMed ID: 12603837
[TBL] [Abstract][Full Text] [Related]
6. Toward the structure of presenilin/γ-secretase and presenilin homologs.
Wolfe MS
Biochim Biophys Acta; 2013 Dec; 1828(12):2886-97. PubMed ID: 24099007
[TBL] [Abstract][Full Text] [Related]
7. Intracellular trafficking of presenilin 1 is regulated by beta-amyloid precursor protein and phospholipase D1.
Liu Y; Zhang YW; Wang X; Zhang H; You X; Liao FF; Xu H
J Biol Chem; 2009 May; 284(18):12145-52. PubMed ID: 19276086
[TBL] [Abstract][Full Text] [Related]
8. Minor contribution of presenilin 2 for γ-secretase activity in mouse embryonic fibroblasts and adult mouse brain.
Frånberg J; Svensson AI; Winblad B; Karlström H; Frykman S
Biochem Biophys Res Commun; 2011 Jan; 404(1):564-8. PubMed ID: 21146496
[TBL] [Abstract][Full Text] [Related]
9. Functional gamma-secretase complex assembly in Golgi/trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and gamma-secretase substrates.
Baulac S; LaVoie MJ; Kimberly WT; Strahle J; Wolfe MS; Selkoe DJ; Xia W
Neurobiol Dis; 2003 Nov; 14(2):194-204. PubMed ID: 14572442
[TBL] [Abstract][Full Text] [Related]
10. Quantitative comparison of presenilin protein expression reveals greater activity of PS2-γ-secretase.
Eccles MK; Main N; Carlessi R; Armstrong AM; Sabale M; Roberts-Mok B; Tirnitz-Parker JEE; Agostino M; Groth D; Fraser PE; Verdile G
FASEB J; 2024 Jan; 38(1):e23396. PubMed ID: 38156414
[TBL] [Abstract][Full Text] [Related]
11. Signature amyloid β profiles are produced by different γ-secretase complexes.
Acx H; Chávez-Gutiérrez L; Serneels L; Lismont S; Benurwar M; Elad N; De Strooper B
J Biol Chem; 2014 Feb; 289(7):4346-55. PubMed ID: 24338474
[TBL] [Abstract][Full Text] [Related]
12. Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components.
Zhang YW; Luo WJ; Wang H; Lin P; Vetrivel KS; Liao F; Li F; Wong PC; Farquhar MG; Thinakaran G; Xu H
J Biol Chem; 2005 Apr; 280(17):17020-6. PubMed ID: 15711015
[TBL] [Abstract][Full Text] [Related]
13. Evidence that enzyme processivity mediates differential Aβ production by PS1 and PS2.
Pintchovski SA; Schenk DB; Basi GS
Curr Alzheimer Res; 2013 Jan; 10(1):4-10. PubMed ID: 22950863
[TBL] [Abstract][Full Text] [Related]
14. gamma-Secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease.
Serneels L; Van Biervliet J; Craessaerts K; Dejaegere T; Horré K; Van Houtvin T; Esselmann H; Paul S; Schäfer MK; Berezovska O; Hyman BT; Sprangers B; Sciot R; Moons L; Jucker M; Yang Z; May PC; Karran E; Wiltfang J; D'Hooge R; De Strooper B
Science; 2009 May; 324(5927):639-42. PubMed ID: 19299585
[TBL] [Abstract][Full Text] [Related]
15. Dominant negative effect of the loss-of-function γ-secretase mutants on the wild-type enzyme through heterooligomerization.
Zhou R; Yang G; Shi Y
Proc Natl Acad Sci U S A; 2017 Nov; 114(48):12731-12736. PubMed ID: 29078389
[TBL] [Abstract][Full Text] [Related]
16. Gamma-secretase composed of PS1/Pen2/Aph1a can cleave notch and amyloid precursor protein in the absence of nicastrin.
Zhao G; Liu Z; Ilagan MX; Kopan R
J Neurosci; 2010 Feb; 30(5):1648-56. PubMed ID: 20130175
[TBL] [Abstract][Full Text] [Related]
17. Identification of distinct gamma-secretase complexes with different APH-1 variants.
Shirotani K; Edbauer D; Prokop S; Haass C; Steiner H
J Biol Chem; 2004 Oct; 279(40):41340-5. PubMed ID: 15286082
[TBL] [Abstract][Full Text] [Related]
18. Identification of presenilin 1-selective γ-secretase inhibitors with reconstituted γ-secretase complexes.
Lee J; Song L; Terracina G; Bara T; Josien H; Asberom T; Sasikumar TK; Burnett DA; Clader J; Parker EM; Zhang L
Biochemistry; 2011 Jun; 50(22):4973-80. PubMed ID: 21528914
[TBL] [Abstract][Full Text] [Related]
19. Specificity of presenilin-1- and presenilin-2-dependent γ-secretases towards substrate processing.
Stanga S; Vrancx C; Tasiaux B; Marinangeli C; Karlström H; Kienlen-Campard P
J Cell Mol Med; 2018 Feb; 22(2):823-833. PubMed ID: 28994238
[TBL] [Abstract][Full Text] [Related]
20. Alzheimer's disease-linked mutations in presenilin-1 result in a drastic loss of activity in purified γ-secretase complexes.
Cacquevel M; Aeschbach L; Houacine J; Fraering PC
PLoS One; 2012; 7(4):e35133. PubMed ID: 22529981
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
