BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

277 related articles for article (PubMed ID: 27066977)

  • 41. Mechanism of free radical nitric oxide-mediated Ras guanine nucleotide dissociation.
    Heo J; Prutzman KC; Mocanu V; Campbell SL
    J Mol Biol; 2005 Mar; 346(5):1423-40. PubMed ID: 15713491
    [TBL] [Abstract][Full Text] [Related]  

  • 42. KRAS Switch Mutants D33E and A59G Crystallize in the State 1 Conformation.
    Lu J; Bera AK; Gondi S; Westover KD
    Biochemistry; 2018 Jan; 57(3):324-333. PubMed ID: 29235861
    [TBL] [Abstract][Full Text] [Related]  

  • 43. PPDPF Promotes the Development of Mutant KRAS-Driven Pancreatic Ductal Adenocarcinoma by Regulating the GEF Activity of SOS1.
    Ni QZ; Zhu B; Ji Y; Zheng QW; Liang X; Ma N; Jiang H; Zhang FK; Shang YR; Wang YK; Xu S; Zhang EB; Yuan YM; Chen TW; Yin FF; Cao HJ; Huang JY; Xia J; Ding XF; Qiu XS; Ding K; Song C; Zhou WT; Wu M; Wang K; Lui R; Lin Q; Chen W; Li ZG; Cheng SQ; Wang XF; Xie D; Li JJ
    Adv Sci (Weinh); 2023 Jan; 10(2):e2202448. PubMed ID: 36453576
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices.
    Leshchiner ES; Parkhitko A; Bird GH; Luccarelli J; Bellairs JA; Escudero S; Opoku-Nsiah K; Godes M; Perrimon N; Walensky LD
    Proc Natl Acad Sci U S A; 2015 Feb; 112(6):1761-6. PubMed ID: 25624485
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Three-dimensional structure of p21H-ras and its implications.
    Wittinghofer F
    Semin Cancer Biol; 1992 Aug; 3(4):189-98. PubMed ID: 1421163
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.
    Schweins T; Geyer M; Kalbitzer HR; Wittinghofer A; Warshel A
    Biochemistry; 1996 Nov; 35(45):14225-31. PubMed ID: 8916907
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Mechanisms of guanosine triphosphate hydrolysis by Ras and Ras-GAP proteins as rationalized by ab initio QM/MM simulations.
    Grigorenko BL; Nemukhin AV; Shadrina MS; Topol IA; Burt SK
    Proteins; 2007 Feb; 66(2):456-66. PubMed ID: 17094109
    [TBL] [Abstract][Full Text] [Related]  

  • 48. CrkL plays a role in SDF-1-induced activation of the Raf-1/MEK/Erk pathway through Ras and Rac to mediate chemotactic signaling in hematopoietic cells.
    Arai A; Aoki M; Weihua Y; Jin A; Miura O
    Cell Signal; 2006 Dec; 18(12):2162-71. PubMed ID: 16781119
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Different structural requirements within the switch II region of the Ras protein for interactions with specific downstream targets.
    Moodie SA; Paris M; Villafranca E; Kirshmeier P; Willumsen BM; Wolfman A
    Oncogene; 1995 Aug; 11(3):447-54. PubMed ID: 7630628
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Regulators and effectors of ras proteins.
    Bollag G; McCormick F
    Annu Rev Cell Biol; 1991; 7():601-32. PubMed ID: 1667084
    [No Abstract]   [Full Text] [Related]  

  • 51. Type II cGMP-dependent protein kinase inhibits EGF-triggered signal transduction of the MAPK/ERK-mediated pathway in gastric cancer cells.
    Wu Y; Chen Y; Qu R; Lan T; Sang J
    Oncol Rep; 2012 Feb; 27(2):553-8. PubMed ID: 22012247
    [TBL] [Abstract][Full Text] [Related]  

  • 52. High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling.
    Burns MC; Howes JE; Sun Q; Little AJ; Camper DV; Abbott JR; Phan J; Lee T; Waterson AG; Rossanese OW; Fesik SW
    Anal Biochem; 2018 May; 548():44-52. PubMed ID: 29444450
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Activation of the RAS/RAF/ERK signaling pathway contributes to resistance to sunitinib in thyroid carcinoma cell lines.
    Piscazzi A; Costantino E; Maddalena F; Natalicchio MI; Gerardi AM; Antonetti R; Cignarelli M; Landriscina M
    J Clin Endocrinol Metab; 2012 Jun; 97(6):E898-906. PubMed ID: 22442268
    [TBL] [Abstract][Full Text] [Related]  

  • 54. High-Affinity Interaction of the K-Ras4B Hypervariable Region with the Ras Active Site.
    Chavan TS; Jang H; Khavrutskii L; Abraham SJ; Banerjee A; Freed BC; Johannessen L; Tarasov SG; Gaponenko V; Nussinov R; Tarasova NI
    Biophys J; 2015 Dec; 109(12):2602-2613. PubMed ID: 26682817
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance.
    Lim JKM; Delaidelli A; Minaker SW; Zhang HF; Colovic M; Yang H; Negri GL; von Karstedt S; Lockwood WW; Schaffer P; Leprivier G; Sorensen PH
    Proc Natl Acad Sci U S A; 2019 May; 116(19):9433-9442. PubMed ID: 31000598
    [TBL] [Abstract][Full Text] [Related]  

  • 56. R-Ras is regulated by activators and effectors distinct from those that control Ras function.
    Huff SY; Quilliam LA; Cox AD; Der CJ
    Oncogene; 1997 Jan; 14(2):133-43. PubMed ID: 9010215
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Calmodulin binds to K-Ras, but not to H- or N-Ras, and modulates its downstream signaling.
    Villalonga P; López-Alcalá C; Bosch M; Chiloeches A; Rocamora N; Gil J; Marais R; Marshall CJ; Bachs O; Agell N
    Mol Cell Biol; 2001 Nov; 21(21):7345-54. PubMed ID: 11585916
    [TBL] [Abstract][Full Text] [Related]  

  • 58. MTH1 expression is required for effective transformation by oncogenic HRAS.
    Giribaldi MG; Munoz A; Halvorsen K; Patel A; Rai P
    Oncotarget; 2015 May; 6(13):11519-29. PubMed ID: 25893378
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Co-dependency between KRAS addiction and ARHGEF2 promotes an adaptive escape from MAPK pathway inhibition.
    Kent OA; Sandi MJ; Rottapel R
    Small GTPases; 2019 Nov; 10(6):441-448. PubMed ID: 28656876
    [TBL] [Abstract][Full Text] [Related]  

  • 60. The structure of substrate-free microbial ribonuclease binase and of its complexes with 3'GMP and sulfate ions.
    Polyakov KM; Lebedev AA; Okorokov AL; Panov KI; Schulga AA; Pavlovsky AG; Karpeisky MY; Dodson GG
    Acta Crystallogr D Biol Crystallogr; 2002 May; 58(Pt 5):744-50. PubMed ID: 11976484
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.