211 related articles for article (PubMed ID: 27068745)
1. An Alzheimer Disease-linked Rare Mutation Potentiates Netrin Receptor Uncoordinated-5C-induced Signaling That Merges with Amyloid β Precursor Protein Signaling.
Hashimoto Y; Toyama Y; Kusakari S; Nawa M; Matsuoka M
J Biol Chem; 2016 Jun; 291(23):12282-93. PubMed ID: 27068745
[TBL] [Abstract][Full Text] [Related]
2. Amyloid precursor protein regulates netrin-1-mediated commissural axon outgrowth.
Rama N; Goldschneider D; Corset V; Lambert J; Pays L; Mehlen P
J Biol Chem; 2012 Aug; 287(35):30014-23. PubMed ID: 22782894
[TBL] [Abstract][Full Text] [Related]
3. Down syndrome cell adhesion molecule (DSCAM) associates with uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse.
Purohit AA; Li W; Qu C; Dwyer T; Shao Q; Guan KL; Liu G
J Biol Chem; 2012 Aug; 287(32):27126-38. PubMed ID: 22685302
[TBL] [Abstract][Full Text] [Related]
4. Netrin-1 receptor UNC5C cleavage by active δ-secretase enhances neurodegeneration, promoting Alzheimer's disease pathologies.
Chen G; Kang SS; Wang Z; Ahn EH; Xia Y; Liu X; Sandoval IM; Manfredsson FP; Zhang Z; Ye K
Sci Adv; 2021 Apr; 7(16):. PubMed ID: 33863723
[TBL] [Abstract][Full Text] [Related]
5. A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death.
Wetzel-Smith MK; Hunkapiller J; Bhangale TR; Srinivasan K; Maloney JA; Atwal JK; Sa SM; Yaylaoglu MB; Foreman O; Ortmann W; Rathore N; Hansen DV; Tessier-Lavigne M; ; Mayeux R; Pericak-Vance M; Haines J; Farrer LA; Schellenberg GD; Goate A; Behrens TW; Cruchaga C; Watts RJ; Graham RR
Nat Med; 2014 Dec; 20(12):1452-7. PubMed ID: 25419706
[TBL] [Abstract][Full Text] [Related]
6. MOCA is an integrator of the neuronal death signals that are activated by familial Alzheimer's disease-related mutants of amyloid β precursor protein and presenilins.
Tachi N; Hashimoto Y; Matsuoka M
Biochem J; 2012 Mar; 442(2):413-22. PubMed ID: 22115042
[TBL] [Abstract][Full Text] [Related]
7. A mutation protective against Alzheimer's disease renders amyloid β precursor protein incapable of mediating neurotoxicity.
Hashimoto Y; Matsuoka M
J Neurochem; 2014 Jul; 130(2):291-300. PubMed ID: 24646423
[TBL] [Abstract][Full Text] [Related]
8. Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome.
Salminen A; Kaarniranta K; Kauppinen A; Ojala J; Haapasalo A; Soininen H; Hiltunen M
Prog Neurobiol; 2013; 106-107():33-54. PubMed ID: 23827971
[TBL] [Abstract][Full Text] [Related]
9. DNA synthesis and neuronal apoptosis caused by familial Alzheimer disease mutants of the amyloid precursor protein are mediated by the p21 activated kinase PAK3.
McPhie DL; Coopersmith R; Hines-Peralta A; Chen Y; Ivins KJ; Manly SP; Kozlowski MR; Neve KA; Neve RL
J Neurosci; 2003 Jul; 23(17):6914-27. PubMed ID: 12890786
[TBL] [Abstract][Full Text] [Related]
10. Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase.
Mudher A; Chapman S; Richardson J; Asuni A; Gibb G; Pollard C; Killick R; Iqbal T; Raymond L; Varndell I; Sheppard P; Makoff A; Gower E; Soden PE; Lewis P; Murphy M; Golde TE; Rupniak HT; Anderton BH; Lovestone S
J Neurosci; 2001 Jul; 21(14):4987-95. PubMed ID: 11438574
[TBL] [Abstract][Full Text] [Related]
11. The cytoplasmic domain of Alzheimer's amyloid-beta protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization.
Hashimoto Y; Niikura T; Chiba T; Tsukamoto E; Kadowaki H; Nishitoh H; Yamagishi Y; Ishizaka M; Yamada M; Nawa M; Terashita K; Aiso S; Ichijo H; Nishimoto I
J Pharmacol Exp Ther; 2003 Sep; 306(3):889-902. PubMed ID: 12829723
[TBL] [Abstract][Full Text] [Related]
12. Netrin-1 interacts with amyloid precursor protein and regulates amyloid-beta production.
Lourenço FC; Galvan V; Fombonne J; Corset V; Llambi F; Müller U; Bredesen DE; Mehlen P
Cell Death Differ; 2009 May; 16(5):655-63. PubMed ID: 19148186
[TBL] [Abstract][Full Text] [Related]
13. Transforming growth factor beta2 is a neuronal death-inducing ligand for amyloid-beta precursor protein.
Hashimoto Y; Chiba T; Yamada M; Nawa M; Kanekura K; Suzuki H; Terashita K; Aiso S; Nishimoto I; Matsuoka M
Mol Cell Biol; 2005 Nov; 25(21):9304-17. PubMed ID: 16227582
[TBL] [Abstract][Full Text] [Related]
14. Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway.
Marques CA; Keil U; Bonert A; Steiner B; Haass C; Muller WE; Eckert A
J Biol Chem; 2003 Jul; 278(30):28294-302. PubMed ID: 12730216
[TBL] [Abstract][Full Text] [Related]
15. Molecular characterization of neurohybrid cell death induced by Alzheimer's amyloid-beta peptides via p75NTR/PLAIDD.
Hashimoto Y; Kaneko Y; Tsukamoto E; Frankowski H; Kouyama K; Kita Y; Niikura T; Aiso S; Bredesen DE; Matsuoka M; Nishimoto I
J Neurochem; 2004 Aug; 90(3):549-58. PubMed ID: 15255932
[TBL] [Abstract][Full Text] [Related]
16. Interaction of ASK1 and the beta-amyloid precursor protein in a stress-signaling complex.
Galvan V; Banwait S; Spilman P; Gorostiza OF; Peel A; Ataie M; Crippen D; Huang W; Sidhu G; Ichijo H; Bredesen DE
Neurobiol Dis; 2007 Oct; 28(1):65-75. PubMed ID: 17719230
[TBL] [Abstract][Full Text] [Related]
17. Anti-apoptotic wild-type Alzheimer amyloid precursor protein signaling involves the p38 mitogen-activated protein kinase/MEF2 pathway.
Burton TR; Dibrov A; Kashour T; Amara FM
Brain Res Mol Brain Res; 2002 Dec; 108(1-2):102-20. PubMed ID: 12480183
[TBL] [Abstract][Full Text] [Related]
18. TAG-1 is an inhibitor of TGFbeta2-induced neuronal death via amyloid beta precursor protein.
Tachi N; Hashimoto Y; Nawa M; Matsuoka M
Biochem Biophys Res Commun; 2010 Mar; 394(1):119-25. PubMed ID: 20184861
[TBL] [Abstract][Full Text] [Related]
19. Characterization of V642I-AbetaPP-induced cytotoxicity in primary neurons.
Niikura T; Yamada M; Chiba T; Aiso S; Matsuoka M; Nishimoto I
J Neurosci Res; 2004 Jul; 77(1):54-62. PubMed ID: 15197738
[TBL] [Abstract][Full Text] [Related]
20. Uncoupling of UNC5C with Polymerized TUBB3 in Microtubules Mediates Netrin-1 Repulsion.
Shao Q; Yang T; Huang H; Alarmanazi F; Liu G
J Neurosci; 2017 Jun; 37(23):5620-5633. PubMed ID: 28483977
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
