118 related articles for article (PubMed ID: 27071702)
1. Pyrazinamide induced hepatic injury in rats through inhibiting the PPARα pathway.
Zhang Y; Guo H; Hassan HM; Ding PP; Su Y; Song Y; Wang T; Sun L; Zhang L; Jiang Z
J Appl Toxicol; 2016 Dec; 36(12):1579-1590. PubMed ID: 27071702
[TBL] [Abstract][Full Text] [Related]
2. Gene expression profiling reveals potential key pathways involved in pyrazinamide-mediated hepatotoxicity in Wistar rats.
Zhang Y; Jiang Z; Su Y; Chen M; Li F; Liu L; Sun L; Wang Y; Zhang S; Zhang L
J Appl Toxicol; 2013 Aug; 33(8):807-19. PubMed ID: 22431067
[TBL] [Abstract][Full Text] [Related]
3. Liver Fatty Acid Binding Protein Deficiency Provokes Oxidative Stress, Inflammation, and Apoptosis-Mediated Hepatotoxicity Induced by Pyrazinamide in Zebrafish Larvae.
Zhang Y; Liu K; Hassan HM; Guo H; Ding P; Han L; He Q; Chen W; Hsiao CD; Zhang L; Jiang Z
Antimicrob Agents Chemother; 2016 Dec; 60(12):7347-7356. PubMed ID: 27697757
[TBL] [Abstract][Full Text] [Related]
4. Metabolism and Hepatotoxicity of Pyrazinamide, an Antituberculosis Drug.
Hussain Z; Zhu J; Ma X
Drug Metab Dispos; 2021 Aug; 49(8):679-682. PubMed ID: 34074731
[TBL] [Abstract][Full Text] [Related]
5. Pyrazinamide Induced Rat Cholestatic Liver Injury through Inhibition of FXR Regulatory Effect on Bile Acid Synthesis and Transport.
Guo HL; Hassan HM; Zhang Y; Dong SZ; Ding PP; Wang T; Sun LX; Zhang LY; Jiang ZZ
Toxicol Sci; 2016 Aug; 152(2):417-28. PubMed ID: 27255380
[TBL] [Abstract][Full Text] [Related]
6. Dietary isoflavone supplementation modulates lipid metabolism via PPARalpha-dependent and -independent mechanisms.
Mezei O; Li Y; Mullen E; Ross-Viola JS; Shay NF
Physiol Genomics; 2006 Jun; 26(1):8-14. PubMed ID: 16507786
[TBL] [Abstract][Full Text] [Related]
7. PPAR
Mandala A; Chen WJ; Armstrong A; Malhotra MR; Chavalmane S; McCommis KS; Chen A; Carpenter D; Biswas P; Gnana-Prakasam JP
Am J Physiol Gastrointest Liver Physiol; 2021 Sep; 321(4):G262-G269. PubMed ID: 34287090
[TBL] [Abstract][Full Text] [Related]
8. Disruption of hepatic lipid homeostasis in mice after amiodarone treatment is associated with peroxisome proliferator-activated receptor-alpha target gene activation.
McCarthy TC; Pollak PT; Hanniman EA; Sinal CJ
J Pharmacol Exp Ther; 2004 Dec; 311(3):864-73. PubMed ID: 15265979
[TBL] [Abstract][Full Text] [Related]
9. A novel mechanism underlies the hepatotoxicity of pyrazinamide.
Shih TY; Pai CY; Yang P; Chang WL; Wang NC; Hu OY
Antimicrob Agents Chemother; 2013 Apr; 57(4):1685-90. PubMed ID: 23357778
[TBL] [Abstract][Full Text] [Related]
10. Transcriptome analyses demonstrate that Peroxisome Proliferator-Activated Receptor α (PPARα) activity of an ultraviolet absorber, 2-(2'-hydroxy-3',5'-di-tert-butylphenyl)benzotriazole, as possible mechanism of their toxicity and the gender differences.
Hirata-Koizumi M; Ise R; Kato H; Matsuyama T; Nishimaki-Mogami T; Takahashi M; Ono A; Ema M; Hirose A
J Toxicol Sci; 2016; 41(5):693-700. PubMed ID: 27665778
[TBL] [Abstract][Full Text] [Related]
11. PPARα/γ agonists and antagonists differently affect hepatic lipid metabolism, oxidative stress and inflammatory cytokine production in steatohepatitic rats.
Zhang Y; Cui Y; Wang XL; Shang X; Qi ZG; Xue J; Zhao X; Deng M; Xie ML
Cytokine; 2015 Sep; 75(1):127-35. PubMed ID: 26194065
[TBL] [Abstract][Full Text] [Related]
12. Bile acids, lipid and purine metabolism involved in hepatotoxicity of first-line anti-tuberculosis drugs.
Liu L; Li X; Huang C; Bian Y; Liu X; Cao J; Qu W; Miao L
Expert Opin Drug Metab Toxicol; 2020 Jun; 16(6):527-537. PubMed ID: 32436768
[TBL] [Abstract][Full Text] [Related]
13. PPAR-alpha dependent regulation of vanin-1 mediates hepatic lipid metabolism.
van Diepen JA; Jansen PA; Ballak DB; Hijmans A; Hooiveld GJ; Rommelaere S; Galland F; Naquet P; Rutjes FP; Mensink RP; Schrauwen P; Tack CJ; Netea MG; Kersten S; Schalkwijk J; Stienstra R
J Hepatol; 2014 Aug; 61(2):366-72. PubMed ID: 24751833
[TBL] [Abstract][Full Text] [Related]
14. Influence of peroxisome proliferator-activated receptor-alpha (PPARα) activity on adverse effects associated with amiodarone exposure in mice.
Ernst MC; Sinal CJ; Pollak PT
Pharmacol Res; 2010 Nov; 62(5):408-15. PubMed ID: 20654716
[TBL] [Abstract][Full Text] [Related]
15. Fenofibrate, a peroxisome proliferator-activated receptor α ligand, prevents abnormal liver function induced by a fasting-refeeding process.
Lee JN; Dutta RK; Kim SG; Lim JY; Kim SJ; Choe SK; Yoo KW; Song SR; Park DS; So HS; Park R
Biochem Biophys Res Commun; 2013 Dec; 442(1-2):22-7. PubMed ID: 24211584
[TBL] [Abstract][Full Text] [Related]
16. An Evaluation of the In Vitro Roles and Mechanisms of Silibinin in Reducing Pyrazinamide- and Isoniazid-Induced Hepatocellular Damage.
Goh ZH; Tee JK; Ho HK
Int J Mol Sci; 2020 May; 21(10):. PubMed ID: 32466226
[TBL] [Abstract][Full Text] [Related]
17. Metabolomics approach discriminates toxicity index of pyrazinamide and its metabolic products, pyrazinoic acid and 5-hydroxy pyrazinoic acid.
Rawat A; Chaturvedi S; Singh AK; Guleria A; Dubey D; Keshari AK; Raj V; Rai A; Prakash A; Kumar U; Kumar D; Saha S
Hum Exp Toxicol; 2018 Apr; 37(4):373-389. PubMed ID: 28425350
[TBL] [Abstract][Full Text] [Related]
18. The role of fenofibrate in clinical practice.
Zambon A; Cusi K
Diab Vasc Dis Res; 2007 Sep; 4 Suppl 3():S15-20. PubMed ID: 17935056
[TBL] [Abstract][Full Text] [Related]
19. Protective effect of a 50% hydroalcoholic fruit extract of Emblica officinalis against anti-tuberculosis drugs induced liver toxicity.
Tasduq SA; Kaisar P; Gupta DK; Kapahi BK; Maheshwari HS; Jyotsna S; Johri RK
Phytother Res; 2005 Mar; 19(3):193-7. PubMed ID: 15934014
[TBL] [Abstract][Full Text] [Related]
20. Preventing type 2 diabetes and cardiovascular disease in metabolic syndrome: the role of PPARalpha.
Plutzky J
Diab Vasc Dis Res; 2007 Sep; 4 Suppl 3():S12-4. PubMed ID: 17935055
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
