230 related articles for article (PubMed ID: 27072130)
1. Tumor Suppressor Folliculin Regulates mTORC1 through Primary Cilia.
Zhong M; Zhao X; Li J; Yuan W; Yan G; Tong M; Guo S; Zhu Y; Jiang Y; Liu Y; Jiang Y
J Biol Chem; 2016 May; 291(22):11689-97. PubMed ID: 27072130
[TBL] [Abstract][Full Text] [Related]
2. Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling.
Baba M; Hong SB; Sharma N; Warren MB; Nickerson ML; Iwamatsu A; Esposito D; Gillette WK; Hopkins RF; Hartley JL; Furihata M; Oishi S; Zhen W; Burke TR; Linehan WM; Schmidt LS; Zbar B
Proc Natl Acad Sci U S A; 2006 Oct; 103(42):15552-7. PubMed ID: 17028174
[TBL] [Abstract][Full Text] [Related]
3. Ciliary localization of folliculin mediated via a kinesin-2-binding motif is required for its functions in mTOR regulation and tumor suppression.
Zhang Y; Liu Y; Dai Y; Ren Y; Bao G; Ai B; Jiang Y
FEBS Lett; 2021 Jan; 595(1):123-132. PubMed ID: 33064845
[TBL] [Abstract][Full Text] [Related]
4. Birt-Hogg-Dubé syndrome: Clinical and molecular aspects of recently identified kidney cancer syndrome.
Hasumi H; Baba M; Hasumi Y; Furuya M; Yao M
Int J Urol; 2016 Mar; 23(3):204-10. PubMed ID: 26608100
[TBL] [Abstract][Full Text] [Related]
5. Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases.
Petit CS; Roczniak-Ferguson A; Ferguson SM
J Cell Biol; 2013 Sep; 202(7):1107-22. PubMed ID: 24081491
[TBL] [Abstract][Full Text] [Related]
6. Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2.
Hasumi Y; Baba M; Ajima R; Hasumi H; Valera VA; Klein ME; Haines DC; Merino MJ; Hong SB; Yamaguchi TP; Schmidt LS; Linehan WM
Proc Natl Acad Sci U S A; 2009 Nov; 106(44):18722-7. PubMed ID: 19850877
[TBL] [Abstract][Full Text] [Related]
7. Regulation of folliculin (the BHD gene product) phosphorylation by Tsc2-mTOR pathway.
Piao X; Kobayashi T; Wang L; Shiono M; Takagi Y; Sun G; Abe M; Hagiwara Y; Zhang D; Okimoto K; Kouchi M; Matsumoto I; Hino O
Biochem Biophys Res Commun; 2009 Nov; 389(1):16-21. PubMed ID: 19695222
[TBL] [Abstract][Full Text] [Related]
8. Primary cilia regulate mTORC1 activity and cell size through Lkb1.
Boehlke C; Kotsis F; Patel V; Braeg S; Voelker H; Bredt S; Beyer T; Janusch H; Hamann C; Gödel M; Müller K; Herbst M; Hornung M; Doerken M; Köttgen M; Nitschke R; Igarashi P; Walz G; Kuehn EW
Nat Cell Biol; 2010 Nov; 12(11):1115-22. PubMed ID: 20972424
[TBL] [Abstract][Full Text] [Related]
9. Folliculin controls lung alveolar enlargement and epithelial cell survival through E-cadherin, LKB1, and AMPK.
Goncharova EA; Goncharov DA; James ML; Atochina-Vasserman EN; Stepanova V; Hong SB; Li H; Gonzales L; Baba M; Linehan WM; Gow AJ; Margulies S; Guttentag S; Schmidt LS; Krymskaya VP
Cell Rep; 2014 Apr; 7(2):412-423. PubMed ID: 24726356
[TBL] [Abstract][Full Text] [Related]
10. Birt-Hogg-Dube syndrome is a novel ciliopathy.
Luijten MN; Basten SG; Claessens T; Vernooij M; Scott CL; Janssen R; Easton JA; Kamps MA; Vreeburg M; Broers JL; van Geel M; Menko FH; Harbottle RP; Nookala RK; Tee AR; Land SC; Giles RH; Coull BJ; van Steensel MA
Hum Mol Genet; 2013 Nov; 22(21):4383-97. PubMed ID: 23784378
[TBL] [Abstract][Full Text] [Related]
11. Unique mutation, accelerated mTOR signaling and angiogenesis in the pulmonary cysts of Birt-Hogg-Dubé syndrome.
Nishii T; Tanabe M; Tanaka R; Matsuzawa T; Okudela K; Nozawa A; Nakatani Y; Furuya M
Pathol Int; 2013 Jan; 63(1):45-55. PubMed ID: 23356225
[TBL] [Abstract][Full Text] [Related]
12. Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation.
Hasumi Y; Baba M; Hasumi H; Huang Y; Lang M; Reindorf R; Oh HB; Sciarretta S; Nagashima K; Haines DC; Schneider MD; Adelstein RS; Schmidt LS; Sadoshima J; Marston Linehan W
Hum Mol Genet; 2014 Nov; 23(21):5706-19. PubMed ID: 24908670
[TBL] [Abstract][Full Text] [Related]
13. The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue.
Wada S; Neinast M; Jang C; Ibrahim YH; Lee G; Babu A; Li J; Hoshino A; Rowe GC; Rhee J; Martina JA; Puertollano R; Blenis J; Morley M; Baur JA; Seale P; Arany Z
Genes Dev; 2016 Nov; 30(22):2551-2564. PubMed ID: 27913603
[TBL] [Abstract][Full Text] [Related]
14. AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR.
Collodet C; Foretz M; Deak M; Bultot L; Metairon S; Viollet B; Lefebvre G; Raymond F; Parisi A; Civiletto G; Gut P; Descombes P; Sakamoto K
FASEB J; 2019 Nov; 33(11):12374-12391. PubMed ID: 31404503
[TBL] [Abstract][Full Text] [Related]
15. Interaction of folliculin (Birt-Hogg-Dubé gene product) with a novel Fnip1-like (FnipL/Fnip2) protein.
Takagi Y; Kobayashi T; Shiono M; Wang L; Piao X; Sun G; Zhang D; Abe M; Hagiwara Y; Takahashi K; Hino O
Oncogene; 2008 Sep; 27(40):5339-47. PubMed ID: 18663353
[TBL] [Abstract][Full Text] [Related]
16. Nutrient-induced FNIP degradation by SCFβ-TRCP regulates FLCN complex localization and promotes renal cancer progression.
Nagashima K; Fukushima H; Shimizu K; Yamada A; Hidaka M; Hasumi H; Ikebe T; Fukumoto S; Okabe K; Inuzuka H
Oncotarget; 2017 Feb; 8(6):9947-9960. PubMed ID: 28039480
[TBL] [Abstract][Full Text] [Related]
17. Renal tumour suppressor function of the Birt-Hogg-Dubé syndrome gene product folliculin.
Hudon V; Sabourin S; Dydensborg AB; Kottis V; Ghazi A; Paquet M; Crosby K; Pomerleau V; Uetani N; Pause A
J Med Genet; 2010 Mar; 47(3):182-9. PubMed ID: 19843504
[TBL] [Abstract][Full Text] [Related]
18. Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion.
Medvetz DA; Khabibullin D; Hariharan V; Ongusaha PP; Goncharova EA; Schlechter T; Darling TN; Hofmann I; Krymskaya VP; Liao JK; Huang H; Henske EP
PLoS One; 2012; 7(11):e47842. PubMed ID: 23139756
[TBL] [Abstract][Full Text] [Related]
19. Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex.
Lawrence RE; Fromm SA; Fu Y; Yokom AL; Kim DJ; Thelen AM; Young LN; Lim CY; Samelson AJ; Hurley JH; Zoncu R
Science; 2019 Nov; 366(6468):971-977. PubMed ID: 31672913
[TBL] [Abstract][Full Text] [Related]
20. Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice.
Huang X; Wullschleger S; Shpiro N; McGuire VA; Sakamoto K; Woods YL; McBurnie W; Fleming S; Alessi DR
Biochem J; 2008 Jun; 412(2):211-21. PubMed ID: 18387000
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
