These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 27073056)

  • 1. Tumour-specific cytotoxicity and structure-activity relationships of novel 1-[3-(2-methoxyethylthio)propionyl]-3,5-bis(benzylidene)-4-piperidones.
    Hossain M; Das U; Umemura N; Sakagami H; Balzarini J; De Clercq E; Kawase M; Dimmock JR
    Bioorg Med Chem; 2016 May; 24(10):2206-14. PubMed ID: 27073056
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 6-Benzylidene-2-[4-(pyridin-3-ylcarboxy)benzylidene]cyclohexanones: A novel cluster of tumour-selective cytotoxins.
    Panda AK; Das U; Umemura N; Sakagami H; Kawase M; Balzarini J; De Clercq E; Dimmock SG; Roayapalley PK; Dimmock JR
    Bioorg Med Chem Lett; 2017 Apr; 27(7):1611-1615. PubMed ID: 28238612
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, antitumor activity evaluation of some new N-aroyl-α,β-unsaturated piperidones with fluorescence.
    Sun J; Wang S; Li H; Jiang W; Hou G; Zhao F; Cong W
    J Enzyme Inhib Med Chem; 2016; 31(3):495-502. PubMed ID: 26382011
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 3,5-Bis(benzylidene)-1-[4-2-(morpholin-4-yl)ethoxyphenylcarbonyl]-4-piperidone hydrochloride: a lead tumor-specific cytotoxin which induces apoptosis and autophagy.
    Das U; Sakagami H; Chu Q; Wang Q; Kawase M; Selvakumar P; Sharma RK; Dimmock JR
    Bioorg Med Chem Lett; 2010 Feb; 20(3):912-7. PubMed ID: 20064715
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and cytotoxic properties of novel 1-[4-(2-alkylaminoethoxy)phenylcarbonyl]-3,5-bis(arylidene)-4-piperidones and related compounds.
    Das U; Alcorn J; Shrivastav A; Sharma RK; De Clercq E; Balzarini J; Dimmock JR
    Eur J Med Chem; 2007 Jan; 42(1):71-80. PubMed ID: 16996657
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel hybrid molecules of 3,5-bis(benzylidene)-4-piperidones and dichloroacetic acid which demonstrate potent tumour-selective cytotoxicity.
    Hossain M; Das S; Das U; Doroudi A; Zhu J; Dimmock JR
    Bioorg Med Chem Lett; 2020 Feb; 30(3):126878. PubMed ID: 31864797
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel class of piperidones exhibit potent, selective and pro-apoptotic anti-leukemia properties.
    Nunes LM; Hossain M; Varela-Ramirez A; DAS U; Ayala-Marin YM; Dimmock JR; Aguilera RJ
    Oncol Lett; 2016 Jun; 11(6):3842-3848. PubMed ID: 27313705
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dimeric 3,5-bis(benzylidene)-4-piperidones: a novel cluster of tumour-selective cytotoxins possessing multidrug-resistant properties.
    Das S; Das U; Sakagami H; Umemura N; Iwamoto S; Matsuta T; Kawase M; Molnár J; Serly J; Gorecki DK; Dimmock JR
    Eur J Med Chem; 2012 May; 51():193-9. PubMed ID: 22409967
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 1-[4-(2-Dimethylaminoethoxy)phenylcarbonyl]-3,5-Bis(3,4,5-Trimethoxybenzylidene)- 4-Piperidone Hydrochloride and Related Compounds: Potent Cytotoxins Demonstrate Greater Toxicity to Neoplasms than Non- Malignant Cells.
    Roayapalley PK; Dimmock JR; Sakagami H; Okudaira N; Sharma RK; Das U
    Med Chem; 2022; 18(9):1001-1012. PubMed ID: 35319387
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 3,5-Bis(3-alkylaminomethyl-4-hydroxybenzylidene)-4-piperidones: A Novel Class of Potent Tumor-Selective Cytotoxins.
    Karki SS; Das U; Umemura N; Sakagami H; Iwamoto S; Kawase M; Balzarini J; De Clercq E; Dimmock SG; Dimmock JR
    J Med Chem; 2016 Jan; 59(2):763-9. PubMed ID: 26727215
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Curcumin-inspired cytotoxic 3,5-bis(arylmethylene)-1-(N-(ortho-substituted aryl)maleamoyl)-4-piperidones: A novel group of topoisomerase II alpha inhibitors.
    Jha A; Duffield KM; Ness MR; Ravoori S; Andrews G; Bhullar KS; Rupasinghe HP; Balzarini J
    Bioorg Med Chem; 2015 Oct; 23(19):6404-17. PubMed ID: 26456623
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological evaluation of 1,5-bis(4-hydroxy-3-methoxyphenyl)penta-1,4-dien-3-one and its aminomethyl derivatives.
    Yerdelen KO; Gul HI; Sakagami H; Umemura N
    J Enzyme Inhib Med Chem; 2015 Jun; 30(3):383-8. PubMed ID: 25068729
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 1-[3-(2-Hydroxyethylsulfanyl)propanoyl]-3,5-bis(benzylidene)-4-piperidones: A novel cluster of P-glycoprotein dependent multidrug resistance modulators.
    Das U; Pati HN; Baráth Z; Csonka Á; Molnár J; Dimmock JR
    Bioorg Med Chem Lett; 2016 Feb; 26(4):1319-21. PubMed ID: 26796064
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cytotoxic N-[4-(3-aryl-3-oxo-1-propenyl)phenylcarbonyl]-3,5-bis(phenylmethylene)-4-piperidones and related compounds.
    Dimmock JR; Jha A; Zello GA; Quail JW; Oloo EO; Nienaber KH; Kowalczyk ES; Allen TM; Santos CL; De Clercq E; Balzarini J; Manavathu EK; Stables JP
    Eur J Med Chem; 2002 Dec; 37(12):961-72. PubMed ID: 12660021
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The cytotoxic properties and preferential toxicity to tumour cells displayed by some 2,4-bis(benzylidene)-8-methyl-8-azabicyclo[3.2.1] octan-3-ones and 3,5-bis(benzylidene)-1-methyl-4-piperidones.
    Pati HN; Das U; Das S; Bandy B; De Clercq E; Balzarini J; Kawase M; Sakagami H; Quail JW; Stables JP; Dimmock JR
    Eur J Med Chem; 2009 Jan; 44(1):54-62. PubMed ID: 18468733
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel 3,5-bis(arylidene)-4-oxo-1-piperidinyl dimers: structure-activity relationships and potent antileukemic and antilymphoma cytotoxicity.
    Santiago-Vazquez Y; Das S; Das U; Robles-Escajeda E; Ortega NM; Lema C; Varela-Ramírez A; Aguilera RJ; Balzarini J; De Clercq E; Dimmock SG; Gorecki DK; Dimmock JR
    Eur J Med Chem; 2014 Apr; 77():315-22. PubMed ID: 24657568
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel Curcumin Inspired Antineoplastic 1-Sulfonyl-4-Piperidones: Design, Synthesis and Molecular Modeling Studies.
    Fawzy NG; Panda SS; Fayad W; El-Manawaty MA; Srour AM; Girgis AS
    Anticancer Agents Med Chem; 2019; 19(8):1069-1078. PubMed ID: 30961509
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytotoxic 3,5-bis(benzylidene)piperidin-4-ones and N-acyl analogs displaying selective toxicity for malignant cells.
    Pati HN; Das U; Quail JW; Kawase M; Sakagami H; Dimmock JR
    Eur J Med Chem; 2008 Jan; 43(1):1-7. PubMed ID: 17499885
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and bioevaluation of novel N-substituted-3,5-bis(arylidene)-4-piperidone derivatives as cytotoxic and antitumor agents with fluorescent properties.
    Sun J; Zhang S; Yu C; Hou G; Zhang X; Li K; Zhao F
    Chem Biol Drug Des; 2014 Apr; 83(4):392-400. PubMed ID: 24148151
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CoMFA and CoMSIA studies on 1,3-bis(benzylidene)-3,4-dihydro-1H-naphthalen-2-one, 2,6-bis(benzylidene)cyclohexanone, and 3,5-bis(benzylidene)-4-piperidone series of cytotoxic compounds.
    Patel MR; Dimmock JR; Talele TT
    J Chem Inf Model; 2007; 47(6):2110-23. PubMed ID: 17944456
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.