147 related articles for article (PubMed ID: 27073056)
1. Tumour-specific cytotoxicity and structure-activity relationships of novel 1-[3-(2-methoxyethylthio)propionyl]-3,5-bis(benzylidene)-4-piperidones.
Hossain M; Das U; Umemura N; Sakagami H; Balzarini J; De Clercq E; Kawase M; Dimmock JR
Bioorg Med Chem; 2016 May; 24(10):2206-14. PubMed ID: 27073056
[TBL] [Abstract][Full Text] [Related]
2. 6-Benzylidene-2-[4-(pyridin-3-ylcarboxy)benzylidene]cyclohexanones: A novel cluster of tumour-selective cytotoxins.
Panda AK; Das U; Umemura N; Sakagami H; Kawase M; Balzarini J; De Clercq E; Dimmock SG; Roayapalley PK; Dimmock JR
Bioorg Med Chem Lett; 2017 Apr; 27(7):1611-1615. PubMed ID: 28238612
[TBL] [Abstract][Full Text] [Related]
3. Synthesis, antitumor activity evaluation of some new N-aroyl-α,β-unsaturated piperidones with fluorescence.
Sun J; Wang S; Li H; Jiang W; Hou G; Zhao F; Cong W
J Enzyme Inhib Med Chem; 2016; 31(3):495-502. PubMed ID: 26382011
[TBL] [Abstract][Full Text] [Related]
4. 3,5-Bis(benzylidene)-1-[4-2-(morpholin-4-yl)ethoxyphenylcarbonyl]-4-piperidone hydrochloride: a lead tumor-specific cytotoxin which induces apoptosis and autophagy.
Das U; Sakagami H; Chu Q; Wang Q; Kawase M; Selvakumar P; Sharma RK; Dimmock JR
Bioorg Med Chem Lett; 2010 Feb; 20(3):912-7. PubMed ID: 20064715
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and cytotoxic properties of novel 1-[4-(2-alkylaminoethoxy)phenylcarbonyl]-3,5-bis(arylidene)-4-piperidones and related compounds.
Das U; Alcorn J; Shrivastav A; Sharma RK; De Clercq E; Balzarini J; Dimmock JR
Eur J Med Chem; 2007 Jan; 42(1):71-80. PubMed ID: 16996657
[TBL] [Abstract][Full Text] [Related]
6. Novel hybrid molecules of 3,5-bis(benzylidene)-4-piperidones and dichloroacetic acid which demonstrate potent tumour-selective cytotoxicity.
Hossain M; Das S; Das U; Doroudi A; Zhu J; Dimmock JR
Bioorg Med Chem Lett; 2020 Feb; 30(3):126878. PubMed ID: 31864797
[TBL] [Abstract][Full Text] [Related]
7. A novel class of piperidones exhibit potent, selective and pro-apoptotic anti-leukemia properties.
Nunes LM; Hossain M; Varela-Ramirez A; DAS U; Ayala-Marin YM; Dimmock JR; Aguilera RJ
Oncol Lett; 2016 Jun; 11(6):3842-3848. PubMed ID: 27313705
[TBL] [Abstract][Full Text] [Related]
8. Dimeric 3,5-bis(benzylidene)-4-piperidones: a novel cluster of tumour-selective cytotoxins possessing multidrug-resistant properties.
Das S; Das U; Sakagami H; Umemura N; Iwamoto S; Matsuta T; Kawase M; Molnár J; Serly J; Gorecki DK; Dimmock JR
Eur J Med Chem; 2012 May; 51():193-9. PubMed ID: 22409967
[TBL] [Abstract][Full Text] [Related]
9. 1-[4-(2-Dimethylaminoethoxy)phenylcarbonyl]-3,5-Bis(3,4,5-Trimethoxybenzylidene)- 4-Piperidone Hydrochloride and Related Compounds: Potent Cytotoxins Demonstrate Greater Toxicity to Neoplasms than Non- Malignant Cells.
Roayapalley PK; Dimmock JR; Sakagami H; Okudaira N; Sharma RK; Das U
Med Chem; 2022; 18(9):1001-1012. PubMed ID: 35319387
[TBL] [Abstract][Full Text] [Related]
10. 3,5-Bis(3-alkylaminomethyl-4-hydroxybenzylidene)-4-piperidones: A Novel Class of Potent Tumor-Selective Cytotoxins.
Karki SS; Das U; Umemura N; Sakagami H; Iwamoto S; Kawase M; Balzarini J; De Clercq E; Dimmock SG; Dimmock JR
J Med Chem; 2016 Jan; 59(2):763-9. PubMed ID: 26727215
[TBL] [Abstract][Full Text] [Related]
11. Curcumin-inspired cytotoxic 3,5-bis(arylmethylene)-1-(N-(ortho-substituted aryl)maleamoyl)-4-piperidones: A novel group of topoisomerase II alpha inhibitors.
Jha A; Duffield KM; Ness MR; Ravoori S; Andrews G; Bhullar KS; Rupasinghe HP; Balzarini J
Bioorg Med Chem; 2015 Oct; 23(19):6404-17. PubMed ID: 26456623
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and biological evaluation of 1,5-bis(4-hydroxy-3-methoxyphenyl)penta-1,4-dien-3-one and its aminomethyl derivatives.
Yerdelen KO; Gul HI; Sakagami H; Umemura N
J Enzyme Inhib Med Chem; 2015 Jun; 30(3):383-8. PubMed ID: 25068729
[TBL] [Abstract][Full Text] [Related]
13. 1-[3-(2-Hydroxyethylsulfanyl)propanoyl]-3,5-bis(benzylidene)-4-piperidones: A novel cluster of P-glycoprotein dependent multidrug resistance modulators.
Das U; Pati HN; Baráth Z; Csonka Á; Molnár J; Dimmock JR
Bioorg Med Chem Lett; 2016 Feb; 26(4):1319-21. PubMed ID: 26796064
[TBL] [Abstract][Full Text] [Related]
14. Cytotoxic N-[4-(3-aryl-3-oxo-1-propenyl)phenylcarbonyl]-3,5-bis(phenylmethylene)-4-piperidones and related compounds.
Dimmock JR; Jha A; Zello GA; Quail JW; Oloo EO; Nienaber KH; Kowalczyk ES; Allen TM; Santos CL; De Clercq E; Balzarini J; Manavathu EK; Stables JP
Eur J Med Chem; 2002 Dec; 37(12):961-72. PubMed ID: 12660021
[TBL] [Abstract][Full Text] [Related]
15. The cytotoxic properties and preferential toxicity to tumour cells displayed by some 2,4-bis(benzylidene)-8-methyl-8-azabicyclo[3.2.1] octan-3-ones and 3,5-bis(benzylidene)-1-methyl-4-piperidones.
Pati HN; Das U; Das S; Bandy B; De Clercq E; Balzarini J; Kawase M; Sakagami H; Quail JW; Stables JP; Dimmock JR
Eur J Med Chem; 2009 Jan; 44(1):54-62. PubMed ID: 18468733
[TBL] [Abstract][Full Text] [Related]
16. Novel 3,5-bis(arylidene)-4-oxo-1-piperidinyl dimers: structure-activity relationships and potent antileukemic and antilymphoma cytotoxicity.
Santiago-Vazquez Y; Das S; Das U; Robles-Escajeda E; Ortega NM; Lema C; Varela-Ramírez A; Aguilera RJ; Balzarini J; De Clercq E; Dimmock SG; Gorecki DK; Dimmock JR
Eur J Med Chem; 2014 Apr; 77():315-22. PubMed ID: 24657568
[TBL] [Abstract][Full Text] [Related]
17. Novel Curcumin Inspired Antineoplastic 1-Sulfonyl-4-Piperidones: Design, Synthesis and Molecular Modeling Studies.
Fawzy NG; Panda SS; Fayad W; El-Manawaty MA; Srour AM; Girgis AS
Anticancer Agents Med Chem; 2019; 19(8):1069-1078. PubMed ID: 30961509
[TBL] [Abstract][Full Text] [Related]
18. Cytotoxic 3,5-bis(benzylidene)piperidin-4-ones and N-acyl analogs displaying selective toxicity for malignant cells.
Pati HN; Das U; Quail JW; Kawase M; Sakagami H; Dimmock JR
Eur J Med Chem; 2008 Jan; 43(1):1-7. PubMed ID: 17499885
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and bioevaluation of novel N-substituted-3,5-bis(arylidene)-4-piperidone derivatives as cytotoxic and antitumor agents with fluorescent properties.
Sun J; Zhang S; Yu C; Hou G; Zhang X; Li K; Zhao F
Chem Biol Drug Des; 2014 Apr; 83(4):392-400. PubMed ID: 24148151
[TBL] [Abstract][Full Text] [Related]
20. CoMFA and CoMSIA studies on 1,3-bis(benzylidene)-3,4-dihydro-1H-naphthalen-2-one, 2,6-bis(benzylidene)cyclohexanone, and 3,5-bis(benzylidene)-4-piperidone series of cytotoxic compounds.
Patel MR; Dimmock JR; Talele TT
J Chem Inf Model; 2007; 47(6):2110-23. PubMed ID: 17944456
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]