411 related articles for article (PubMed ID: 27073104)
1. CRISPR-Cas9-modified pfmdr1 protects Plasmodium falciparum asexual blood stages and gametocytes against a class of piperazine-containing compounds but potentiates artemisinin-based combination therapy partner drugs.
Ng CL; Siciliano G; Lee MC; de Almeida MJ; Corey VC; Bopp SE; Bertuccini L; Wittlin S; Kasdin RG; Le Bihan A; Clozel M; Winzeler EA; Alano P; Fidock DA
Mol Microbiol; 2016 Aug; 101(3):381-93. PubMed ID: 27073104
[TBL] [Abstract][Full Text] [Related]
2. Novel polymorphisms in Plasmodium falciparum ABC transporter genes are associated with major ACT antimalarial drug resistance.
Veiga MI; Ferreira PE; Jörnhagen L; Malmberg M; Kone A; Schmidt BA; Petzold M; Björkman A; Nosten F; Gil JP
PLoS One; 2011; 6(5):e20212. PubMed ID: 21633513
[TBL] [Abstract][Full Text] [Related]
3. Selection of Plasmodium falciparum pfcrt and pfmdr1 polymorphisms after treatment with artesunate-amodiaquine fixed dose combination or artemether-lumefantrine in Liberia.
Otienoburu SD; Maïga-Ascofaré O; Schramm B; Jullien V; Jones JJ; Zolia YM; Houzé P; Ashley EA; Kiechel JR; Guérin PJ; Le Bras J; Houzé S
Malar J; 2016 Sep; 15(1):452. PubMed ID: 27596849
[TBL] [Abstract][Full Text] [Related]
4. Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity.
Vanaerschot M; Lucantoni L; Li T; Combrinck JM; Ruecker A; Kumar TRS; Rubiano K; Ferreira PE; Siciliano G; Gulati S; Henrich PP; Ng CL; Murithi JM; Corey VC; Duffy S; Lieberman OJ; Veiga MI; Sinden RE; Alano P; Delves MJ; Lee Sim K; Winzeler EA; Egan TJ; Hoffman SL; Avery VM; Fidock DA
Nat Microbiol; 2017 Oct; 2(10):1403-1414. PubMed ID: 28808258
[TBL] [Abstract][Full Text] [Related]
5. Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number.
Price RN; Uhlemann AC; Brockman A; McGready R; Ashley E; Phaipun L; Patel R; Laing K; Looareesuwan S; White NJ; Nosten F; Krishna S
Lancet; 2004 Jul 31-Aug 6; 364(9432):438-447. PubMed ID: 15288742
[TBL] [Abstract][Full Text] [Related]
6. Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin.
Sidhu AB; Uhlemann AC; Valderramos SG; Valderramos JC; Krishna S; Fidock DA
J Infect Dis; 2006 Aug; 194(4):528-35. PubMed ID: 16845638
[TBL] [Abstract][Full Text] [Related]
7. Modulation of in vitro antimalarial responses by polymorphisms in Plasmodium falciparum ABC transporters (pfmdr1 and pfmdr5).
Gendrot M; Wague Gueye M; Tsombeng Foguim F; Madamet M; Wade KA; Bou Kounta M; Fall M; Diawara S; Benoit N; Lo G; Bercion R; Amalvict R; Mosnier J; Fall B; Briolant S; Diatta B; Pradines B
Acta Trop; 2019 Aug; 196():126-134. PubMed ID: 31108084
[TBL] [Abstract][Full Text] [Related]
8. In vitro selection of Plasmodium falciparum Pfcrt and Pfmdr1 variants by artemisinin.
Njokah MJ; Kang'ethe JN; Kinyua J; Kariuki D; Kimani FT
Malar J; 2016 Jul; 15(1):381. PubMed ID: 27449110
[TBL] [Abstract][Full Text] [Related]
9. A Variant PfCRT Isoform Can Contribute to
Dhingra SK; Redhi D; Combrinck JM; Yeo T; Okombo J; Henrich PP; Cowell AN; Gupta P; Stegman ML; Hoke JM; Cooper RA; Winzeler E; Mok S; Egan TJ; Fidock DA
mBio; 2017 May; 8(3):. PubMed ID: 28487425
[TBL] [Abstract][Full Text] [Related]
10. Expansion of a Specific Plasmodium falciparum PfMDR1 Haplotype in Southeast Asia with Increased Substrate Transport.
Calçada C; Silva M; Baptista V; Thathy V; Silva-Pedrosa R; Granja D; Ferreira PE; Gil JP; Fidock DA; Veiga MI
mBio; 2020 Dec; 11(6):. PubMed ID: 33262257
[TBL] [Abstract][Full Text] [Related]
11. Spatio-temporal distribution of PfMDR1 polymorphism among uncomplicated Plasmodium falciparum malaria cases along international border of north east India.
Goomber S; Mishra N; Anvikar A; Yadav CP; Valecha N
Infect Genet Evol; 2018 Sep; 63():285-290. PubMed ID: 29842979
[TBL] [Abstract][Full Text] [Related]
12. Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling.
Le Bihan A; de Kanter R; Angulo-Barturen I; Binkert C; Boss C; Brun R; Brunner R; Buchmann S; Burrows J; Dechering KJ; Delves M; Ewerling S; Ferrer S; Fischli C; Gamo-Benito FJ; Gnädig NF; Heidmann B; Jiménez-Díaz MB; Leroy D; Martínez MS; Meyer S; Moehrle JJ; Ng CL; Noviyanti R; Ruecker A; Sanz LM; Sauerwein RW; Scheurer C; Schleiferboeck S; Sinden R; Snyder C; Straimer J; Wirjanata G; Marfurt J; Price RN; Weller T; Fischli W; Fidock DA; Clozel M; Wittlin S
PLoS Med; 2016 Oct; 13(10):e1002138. PubMed ID: 27701420
[TBL] [Abstract][Full Text] [Related]
13. K13 mutations and pfmdr1 copy number variation in Plasmodium falciparum malaria in Myanmar.
Win AA; Imwong M; Kyaw MP; Woodrow CJ; Chotivanich K; Hanboonkunupakarn B; Pukrittayakamee S
Malar J; 2016 Feb; 15():110. PubMed ID: 26911145
[TBL] [Abstract][Full Text] [Related]
14. Monitoring of in vitro susceptibilities and molecular markers of resistance of Plasmodium falciparum isolates from Thai-Myanmar border to chloroquine, quinine, mefloquine and artesunate.
Chaijaroenkul W; Wisedpanichkij R; Na-Bangchang K
Acta Trop; 2010 Feb; 113(2):190-4. PubMed ID: 19879850
[TBL] [Abstract][Full Text] [Related]
15. Role of pfmdr1 amplification and expression in induction of resistance to artemisinin derivatives in Plasmodium falciparum.
Chavchich M; Gerena L; Peters J; Chen N; Cheng Q; Kyle DE
Antimicrob Agents Chemother; 2010 Jun; 54(6):2455-64. PubMed ID: 20350946
[TBL] [Abstract][Full Text] [Related]
16. pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum.
Sidhu AB; Valderramos SG; Fidock DA
Mol Microbiol; 2005 Aug; 57(4):913-26. PubMed ID: 16091034
[TBL] [Abstract][Full Text] [Related]
17. pfmdr1 (Plasmodium falciparum multidrug drug resistance gene 1): a pivotal factor in malaria resistance to artemisinin combination therapies.
Gil JP; Krishna S
Expert Rev Anti Infect Ther; 2017 Jun; 15(6):527-543. PubMed ID: 28355493
[TBL] [Abstract][Full Text] [Related]
18. Increased prevalence of the Plasmodium falciparum Pfmdr1 86N genotype among field isolates from Franceville, Gabon after replacement of chloroquine by artemether-lumefantrine and artesunate-mefloquine.
Lekana-Douki JB; Dinzouna Boutamba SD; Zatra R; Zang Edou SE; Ekomy H; Bisvigou U; Toure-Ndouo FS
Infect Genet Evol; 2011 Mar; 11(2):512-7. PubMed ID: 21251998
[TBL] [Abstract][Full Text] [Related]
19. A 2-amino quinoline, 5-(3-(2-(7-chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid, interacts with PfMDR1 and inhibits its drug transport in Plasmodium falciparum.
Edaye S; Reiling SJ; Leimanis ML; Wunderlich J; Rohrbach P; Georges E
Mol Biochem Parasitol; 2014 Jun; 195(1):34-42. PubMed ID: 24914817
[TBL] [Abstract][Full Text] [Related]
20. Prevalent pfmdr1 n86y mutant Plasmodium falciparum in Madagascar despite absence of pfcrt mutant strains.
Rason MA; Andrianantenaina HB; Ariey F; Raveloson A; Domarle O; Randrianarivelojosia M
Am J Trop Med Hyg; 2007 Jun; 76(6):1079-83. PubMed ID: 17556614
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
