BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 27073121)

  • 1. High levels of histone H3 acetylation at the CMV promoter are predictive of stable expression in Chinese hamster ovary cells.
    Moritz B; Woltering L; Becker PB; Göpfert U
    Biotechnol Prog; 2016 May; 32(3):776-86. PubMed ID: 27073121
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Correlation Between Expression of Recombinant Proteins and Abundance of H3K4Me3 on the Enhancer of Human Cytomegalovirus Major Immediate-Early Promoter.
    Soo BPC; Tay J; Ng S; Ho SCL; Yang Y; Chao SH
    Mol Biotechnol; 2017 Aug; 59(8):315-322. PubMed ID: 28664508
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Promoter methylation and transgene copy numbers predict unstable protein production in recombinant Chinese hamster ovary cell lines.
    Osterlehner A; Simmeth S; Göpfert U
    Biotechnol Bioeng; 2011 Nov; 108(11):2670-81. PubMed ID: 21618470
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CMV promoter mutants with a reduced propensity to productivity loss in CHO cells.
    Moritz B; Becker PB; Göpfert U
    Sci Rep; 2015 Nov; 5():16952. PubMed ID: 26581326
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms underlying epigenetic and transcriptional heterogeneity in Chinese hamster ovary (CHO) cell lines.
    Veith N; Ziehr H; MacLeod RA; Reamon-Buettner SM
    BMC Biotechnol; 2016 Jan; 16():6. PubMed ID: 26800878
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Unstable expression of recombinant antibody during long-term culture of CHO cells is accompanied by histone H3 hypoacetylation.
    Paredes V; Park JS; Jeong Y; Yoon J; Baek K
    Biotechnol Lett; 2013 Jul; 35(7):987-93. PubMed ID: 23468139
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA methylation contributes to loss in productivity of monoclonal antibody-producing CHO cell lines.
    Yang Y; Mariati ; Chusainow J; Yap MG
    J Biotechnol; 2010 Jun; 147(3-4):180-5. PubMed ID: 20430058
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insertion of core CpG island element into human CMV promoter for enhancing recombinant protein expression stability in CHO cells.
    Mariati ; Yeo JH; Koh EY; Ho SC; Yang Y
    Biotechnol Prog; 2014; 30(3):523-34. PubMed ID: 24789630
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Histone H3 acetylation and H3 K4 methylation define distinct chromatin regions permissive for transgene expression.
    Yan C; Boyd DD
    Mol Cell Biol; 2006 Sep; 26(17):6357-71. PubMed ID: 16914722
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stability of single copy transgene expression in CHOK1 cells is affected by histone modifications but not by DNA methylation.
    Spencer S; Gugliotta A; Koenitzer J; Hauser H; Wirth D
    J Biotechnol; 2015 Feb; 195():15-29. PubMed ID: 25533398
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lengthening of high-yield production levels of monoclonal antibody-producing Chinese hamster ovary cells by downregulation of breast cancer 1.
    Matsuyama R; Yamano N; Kawamura N; Omasa T
    J Biosci Bioeng; 2017 Mar; 123(3):382-389. PubMed ID: 27742176
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Histone H3 lysine 4 monomethylation (H3K4me1) and H3 lysine 9 monomethylation (H3K9me1): distribution and their association in regulating gene expression under hyperglycaemic/hyperinsulinemic conditions in 3T3 cells.
    Gupta J; Kumar S; Li J; Krishna Murthy Karuturi R; Tikoo K
    Biochimie; 2012 Dec; 94(12):2656-64. PubMed ID: 22951486
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Position effect variegation and epigenetic modification of a transgene in a pig model.
    Yin Z; Kong QR; Zhao ZP; Wu ML; Mu YS; Hu K; Liu ZH
    Genet Mol Res; 2012 Feb; 11(1):355-69. PubMed ID: 22370938
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fam60A plays a role for production stabilities of recombinant CHO cell lines.
    Ritter A; Nuciforo S; Schulze A; Oertli M; Rauschert T; Voedisch B; Geisse S; Jostock T; Laux H
    Biotechnol Bioeng; 2017 Mar; 114(3):701-704. PubMed ID: 27617904
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CRISPR/Cas9-mediated gene knockout for DNA methyltransferase Dnmt3a in CHO cells displays enhanced transgenic expression and long-term stability.
    Jia YL; Guo X; Lu JT; Wang XY; Qiu LL; Wang TY
    J Cell Mol Med; 2018 Sep; 22(9):4106-4116. PubMed ID: 29851281
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A mechanistic understanding of production instability in CHO cell lines expressing recombinant monoclonal antibodies.
    Kim M; O'Callaghan PM; Droms KA; James DC
    Biotechnol Bioeng; 2011 Oct; 108(10):2434-46. PubMed ID: 21538334
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Histone modification in the TGFbetaRII gene promoter and its significance for responsiveness to HDAC inhibitor in lung cancer cell lines.
    Osada H; Tatematsu Y; Sugito N; Horio Y; Takahashi T
    Mol Carcinog; 2005 Dec; 44(4):233-41. PubMed ID: 16163707
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Correlation between histone acetylation and expression of the MYO18B gene in human lung cancer cells.
    Tani M; Ito J; Nishioka M; Kohno T; Tachibana K; Shiraishi M; Takenoshita S; Yokota J
    Genes Chromosomes Cancer; 2004 Jun; 40(2):146-51. PubMed ID: 15101048
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Control of human cytomegalovirus gene expression by differential histone modifications during lytic and latent infection of a monocytic cell line.
    Ioudinkova E; Arcangeletti MC; Rynditch A; De Conto F; Motta F; Covan S; Pinardi F; Razin SV; Chezzi C
    Gene; 2006 Dec; 384():120-8. PubMed ID: 16989963
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluating the use of a CpG free promoter for long-term recombinant protein expression stability in Chinese hamster ovary cells.
    Ho SC; Koh EY; Soo BP; Mariati ; Chao SH; Yang Y
    BMC Biotechnol; 2016 Oct; 16(1):71. PubMed ID: 27756290
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.