These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

407 related articles for article (PubMed ID: 27075612)

  • 1. Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling.
    Keune WJ; Hausmann J; Bolier R; Tolenaars D; Kremer A; Heidebrecht T; Joosten RP; Sunkara M; Morris AJ; Matas-Rico E; Moolenaar WH; Oude Elferink RP; Perrakis A
    Nat Commun; 2016 Apr; 7():11248. PubMed ID: 27075612
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of autotaxin by bile salts and bile salt-like molecules increases its expression by feedback regulation.
    Langedijk JAGM; Tolenaars D; Bolier R; Lee YT; Meurs A; Williamson C; Adorini L; van de Graaf SFJ; Beuers U; Elferink RO
    Biochim Biophys Acta Mol Basis Dis; 2021 Nov; 1867(11):166239. PubMed ID: 34389475
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-function relationships of autotaxin, a secreted lysophospholipase D.
    Hausmann J; Perrakis A; Moolenaar WH
    Adv Biol Regul; 2013 Jan; 53(1):112-7. PubMed ID: 23069371
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Autotaxin: structure-function and signaling.
    Perrakis A; Moolenaar WH
    J Lipid Res; 2014 Jun; 55(6):1010-8. PubMed ID: 24548887
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biological roles of lysophosphatidic acid signaling through its production by autotaxin.
    Okudaira S; Yukiura H; Aoki J
    Biochimie; 2010 Jun; 92(6):698-706. PubMed ID: 20417246
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
    Stein AJ; Bain G; Prodanovich P; Santini AM; Darlington J; Stelzer NM; Sidhu RS; Schaub J; Goulet L; Lonergan D; Calderon I; Evans JF; Hutchinson JH
    Mol Pharmacol; 2015 Dec; 88(6):982-92. PubMed ID: 26371182
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exosomes bind to autotaxin and act as a physiological delivery mechanism to stimulate LPA receptor signalling in cells.
    Jethwa SA; Leah EJ; Zhang Q; Bright NA; Oxley D; Bootman MD; Rudge SA; Wakelam MJ
    J Cell Sci; 2016 Oct; 129(20):3948-3957. PubMed ID: 27557622
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery and synthetic optimization of a novel scaffold for hydrophobic tunnel-targeted autotaxin inhibition.
    Ragle LE; Palanisamy DJ; Joe MJ; Stein RS; Norman DD; Tigyi G; Baker DL; Parrill AL
    Bioorg Med Chem; 2016 Oct; 24(19):4660-4674. PubMed ID: 27544588
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Autotaxin-LPA axis regulates hMSC migration by adherent junction disruption and cytoskeletal rearrangement via LPAR1/3-dependent PKC/GSK3β/β-catenin and PKC/Rho GTPase pathways.
    Ryu JM; Han HJ
    Stem Cells; 2015 Mar; 33(3):819-32. PubMed ID: 25376707
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of the placenta in serum autotaxin elevation during maternal cholestasis.
    Macias RIR; Matilla S; Lozano E; Estiú MC; Oude Elferink RP; Marin JJG
    Am J Physiol Gastrointest Liver Physiol; 2018 Sep; 315(3):G399-G407. PubMed ID: 29927323
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Autotaxin in liver fibrosis.
    Ikeda H; Yatomi Y
    Clin Chim Acta; 2012 Nov; 413(23-24):1817-21. PubMed ID: 22820036
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis of substrate discrimination and integrin binding by autotaxin.
    Hausmann J; Kamtekar S; Christodoulou E; Day JE; Wu T; Fulkerson Z; Albers HM; van Meeteren LA; Houben AJ; van Zeijl L; Jansen S; Andries M; Hall T; Pegg LE; Benson TE; Kasiem M; Harlos K; Kooi CW; Smyth SS; Ovaa H; Bollen M; Morris AJ; Moolenaar WH; Perrakis A
    Nat Struct Mol Biol; 2011 Feb; 18(2):198-204. PubMed ID: 21240271
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Binding of autotaxin to integrins localizes lysophosphatidic acid production to platelets and mammalian cells.
    Fulkerson Z; Wu T; Sunkara M; Kooi CV; Morris AJ; Smyth SS
    J Biol Chem; 2011 Oct; 286(40):34654-63. PubMed ID: 21832043
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The autotaxin-lysophosphatidic acid-lysophosphatidic acid receptor cascade: proposal of a novel potential therapeutic target for treating glioblastoma multiforme.
    Tabuchi S
    Lipids Health Dis; 2015 Jun; 14():56. PubMed ID: 26084470
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A 3D view of autotaxin.
    Nishimasu H; Ishitani R; Aoki J; Nureki O
    Trends Pharmacol Sci; 2012 Mar; 33(3):138-45. PubMed ID: 22277299
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The autotaxin-lysophosphatidic acid pathway in pathogenesis of rheumatoid arthritis.
    Orosa B; García S; Conde C
    Eur J Pharmacol; 2015 Oct; 765():228-33. PubMed ID: 26297977
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lysophosphatidic acid produced by autotaxin acts as an allosteric modulator of its catalytic efficiency.
    Salgado-Polo F; Fish A; Matsoukas MT; Heidebrecht T; Keune WJ; Perrakis A
    J Biol Chem; 2018 Sep; 293(37):14312-14327. PubMed ID: 30026231
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Autotaxin regulates vascular development via multiple lysophosphatidic acid (LPA) receptors in zebrafish.
    Yukiura H; Hama K; Nakanaga K; Tanaka M; Asaoka Y; Okudaira S; Arima N; Inoue A; Hashimoto T; Arai H; Kawahara A; Nishina H; Aoki J
    J Biol Chem; 2011 Dec; 286(51):43972-43983. PubMed ID: 21971049
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by the autotaxin/lysophosphatidic acid axis.
    Bai Z; Cai L; Umemoto E; Takeda A; Tohya K; Komai Y; Veeraveedu PT; Hata E; Sugiura Y; Kubo A; Suematsu M; Hayasaka H; Okudaira S; Aoki J; Tanaka T; Albers HM; Ovaa H; Miyasaka M
    J Immunol; 2013 Mar; 190(5):2036-48. PubMed ID: 23365076
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Autotaxin--an LPA producing enzyme with diverse functions.
    Nakanaga K; Hama K; Aoki J
    J Biochem; 2010 Jul; 148(1):13-24. PubMed ID: 20495010
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.