BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 27082504)

  • 1. SLC22A1/OCT1 Genotype Affects O-desmethyltramadol Exposure in Newborn Infants.
    Matic M; de Wildt SN; Elens L; de Hoon JN; Annaert P; Tibboel D; van Schaik RH; Allegaert K
    Ther Drug Monit; 2016 Aug; 38(4):487-92. PubMed ID: 27082504
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Loss-of-function polymorphisms in the organic cation transporter OCT1 are associated with reduced postoperative tramadol consumption.
    Stamer UM; Musshoff F; Stüber F; Brockmöller J; Steffens M; Tzvetkov MV
    Pain; 2016 Nov; 157(11):2467-2475. PubMed ID: 27541716
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Genetically polymorphic OCT1: another piece in the puzzle of the variable pharmacokinetics and pharmacodynamics of the opioidergic drug tramadol.
    Tzvetkov MV; Saadatmand AR; Lötsch J; Tegeder I; Stingl JC; Brockmöller J
    Clin Pharmacol Ther; 2011 Jul; 90(1):143-50. PubMed ID: 21562485
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Concentrations of tramadol and O-desmethyltramadol enantiomers in different CYP2D6 genotypes.
    Stamer UM; Musshoff F; Kobilay M; Madea B; Hoeft A; Stuber F
    Clin Pharmacol Ther; 2007 Jul; 82(1):41-7. PubMed ID: 17361124
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Postmenstrual age and CYP2D6 polymorphisms determine tramadol o-demethylation in critically ill neonates and infants.
    Allegaert K; van Schaik RH; Vermeersch S; Verbesselt R; Cossey V; Vanhole C; van Fessem M; de Hoon J; van den Anker JN
    Pediatr Res; 2008 Jun; 63(6):674-9. PubMed ID: 18317231
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Covariates of tramadol disposition in the first months of life.
    Allegaert K; van den Anker JN; de Hoon JN; van Schaik RH; Debeer A; Tibboel D; Naulaers G; Anderson BJ
    Br J Anaesth; 2008 Apr; 100(4):525-32. PubMed ID: 18303070
    [TBL] [Abstract][Full Text] [Related]  

  • 7. OCT1 pharmacogenetics in pain management: is a clinical application within reach?
    Tzvetkov MV
    Pharmacogenomics; 2017 Nov; 18(16):1515-1523. PubMed ID: 29061087
    [TBL] [Abstract][Full Text] [Related]  

  • 8. O-demethylation of tramadol in the first months of life.
    Allegaert K; Van den Anker JN; Verbesselt R; de Hoon J; Vanhole C; Tibboel D; Devlieger H
    Eur J Clin Pharmacol; 2005 Dec; 61(11):837-42. PubMed ID: 16283273
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CYP2D6 polymorphism in relation to tramadol metabolism: a study of faroese patients.
    Halling J; Weihe P; Brosen K
    Ther Drug Monit; 2008 Jun; 30(3):271-5. PubMed ID: 18520597
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tramadol and o-desmethyl tramadol clearance maturation and disposition in humans: a pooled pharmacokinetic study.
    Allegaert K; Holford N; Anderson BJ; Holford S; Stuber F; Rochette A; Trocóniz IF; Beier H; de Hoon JN; Pedersen RS; Stamer U
    Clin Pharmacokinet; 2015 Feb; 54(2):167-78. PubMed ID: 25258277
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression of SLC22A1 variants may affect the response of hepatocellular carcinoma and cholangiocarcinoma to sorafenib.
    Herraez E; Lozano E; Macias RI; Vaquero J; Bujanda L; Banales JM; Marin JJ; Briz O
    Hepatology; 2013 Sep; 58(3):1065-73. PubMed ID: 23532667
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6) are associated with long term tramadol treatment-induced oxidative damage and hepatotoxicity.
    Arafa MH; Atteia HH
    Toxicol Appl Pharmacol; 2018 May; 346():37-44. PubMed ID: 29555325
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Population pharmacokinetic analysis of tramadol and
    Lee J; Yoo HD; Bae JW; Lee S; Shin KH
    Drug Des Devel Ther; 2019; 13():1751-1761. PubMed ID: 31213765
    [No Abstract]   [Full Text] [Related]  

  • 14. Tramadol disposition in the very young: an attempt to assess in vivo cytochrome P-450 2D6 activity.
    Allegaert K; Anderson BJ; Verbesselt R; Debeer A; de Hoon J; Devlieger H; Van Den Anker JN; Tibboel D
    Br J Anaesth; 2005 Aug; 95(2):231-9. PubMed ID: 15951326
    [TBL] [Abstract][Full Text] [Related]  

  • 15. OCT1 identity crisis.
    Sreenivasan S; Viljoen CD
    Gene; 2013 Mar; 516(1):190-1. PubMed ID: 23266821
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Impact of CYP genotype and inflammatory markers on the plasma concentrations of tramadol and its demethylated metabolites and drug tolerability in cancer patients.
    Tanaka H; Naito T; Sato H; Hiraide T; Yamada Y; Kawakami J
    Eur J Clin Pharmacol; 2018 Nov; 74(11):1461-1469. PubMed ID: 30051214
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Developmental Changes in Hepatic Organic Cation Transporter OCT1 Protein Expression from Neonates to Children.
    Hahn D; Emoto C; Vinks AA; Fukuda T
    Drug Metab Dispos; 2017 Jan; 45(1):23-26. PubMed ID: 27780835
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of the CYP2D6 gene duplication on the pharmacokinetics and pharmacodynamics of tramadol.
    Kirchheiner J; Keulen JT; Bauer S; Roots I; Brockmöller J
    J Clin Psychopharmacol; 2008 Feb; 28(1):78-83. PubMed ID: 18204346
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of cytochrome P450 (CYP) 2D6 drugs as substrates of human organic cation transporters and multidrug and toxin extrusion proteins.
    Neul C; Hofmann U; Schaeffeler E; Winter S; Klein K; Giacomini KM; Eichelbaum M; Schwab M; Nies AT
    Br J Pharmacol; 2021 Mar; 178(6):1459-1474. PubMed ID: 33434947
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacogenetic aspects of tramadol pharmacokinetics and pharmacodynamics after a single oral dose.
    Bastami S; Haage P; Kronstrand R; Kugelberg FC; Zackrisson AL; Uppugunduri S
    Forensic Sci Int; 2014 May; 238():125-32. PubMed ID: 24709712
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.