BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

338 related articles for article (PubMed ID: 27091443)

  • 1. Metal complexes of 3-(4-bromophenyl)-1-pyridin-2-ylprop-2-en-1-one thiosemicarbazone: cytotoxic activity and investigation on the mode of action of the gold(III) complex.
    Sâmia LB; Parrilha GL; Da Silva JG; Ramos JP; Souza-Fagundes EM; Castelli S; Vutey V; Desideri A; Beraldo H
    Biometals; 2016 Jun; 29(3):515-26. PubMed ID: 27091443
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gold(I) complexes with thiosemicarbazones: cytotoxicity against human tumor cell lines and inhibition of thioredoxin reductase activity.
    Lessa JA; Guerra JC; de Miranda LF; Romeiro CF; Da Silva JG; Mendes IC; Speziali NL; Souza-Fagundes EM; Beraldo H
    J Inorg Biochem; 2011 Dec; 105(12):1729-39. PubMed ID: 22005449
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cytotoxic activity, albumin and DNA binding of new copper(II) complexes with chalcone-derived thiosemicarbazones.
    Da Silva JG; Recio Despaigne AA; Louro SR; Bandeira CC; Souza-Fagundes EM; Beraldo H
    Eur J Med Chem; 2013 Jul; 65():415-26. PubMed ID: 23747809
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human topoisomerase IB is a target of a thiosemicarbazone copper(II) complex.
    Vutey V; Castelli S; D'Annessa I; Sâmia LB; Souza-Fagundes EM; Beraldo H; Desideri A
    Arch Biochem Biophys; 2016 Sep; 606():34-40. PubMed ID: 27431056
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metal complexes with 2-acetylpyridine-N(4)-orthochlorophenylthiosemicarbazone: cytotoxicity and effect on the enzymatic activity of thioredoxin reductase and glutathione reductase.
    Parrilha GL; Ferraz KS; Lessa JA; de Oliveira KN; Rodrigues BL; Ramos JP; Souza-Fagundes EM; Ott I; Beraldo H
    Eur J Med Chem; 2014 Sep; 84():537-44. PubMed ID: 25058344
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cobaltoceniumethynyl gold(I) as an unusual heterodinuclear bioorganometallic fragment to study the biological properties of alkynyl gold complexes.
    Vanicek S; Kopacka H; Wurst K; Vergeiner S; Kankowski S; Schur J; Bildstein B; Ott I
    Dalton Trans; 2016 Jan; 45(4):1345-8. PubMed ID: 26732365
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Spectroscopic and electrochemical characterization of gold(I) and gold(III) complexes with glyoxaldehyde bis(thiosemicarbazones): cytotoxicity against human tumor cell lines and inhibition of thioredoxin reductase activity.
    Lessa JA; Ferraz KS; Guerra JC; de Miranda LF; Romeiro CF; Souza-Fagundes EM; Barbeira PJ; Beraldo H
    Biometals; 2012 Jun; 25(3):587-98. PubMed ID: 22526562
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Potent Inhibition of Thioredoxin Reductase by the Rh Derivatives of Anticancer M(arene/Cp*)(NHC)Cl
    Truong D; Sullivan MP; Tong KKH; Steel TR; Prause A; Lovett JH; Andersen JW; Jamieson SMF; Harris HH; Ott I; Weekley CM; Hummitzsch K; Söhnel T; Hanif M; Metzler-Nolte N; Goldstone DC; Hartinger CG
    Inorg Chem; 2020 Mar; 59(5):3281-3289. PubMed ID: 32073260
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gold(I) thiotetrazolates as thioredoxin reductase inhibitors and antiproliferative agents.
    Serebryanskaya TV; Lyakhov AS; Ivashkevich LS; Schur J; Frias C; Prokop A; Ott I
    Dalton Trans; 2015 Jan; 44(3):1161-9. PubMed ID: 25413270
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel thiosemicarbazones of the ApT and DpT series and their copper complexes: identification of pronounced redox activity and characterization of their antitumor activity.
    Jansson PJ; Sharpe PC; Bernhardt PV; Richardson DR
    J Med Chem; 2010 Aug; 53(15):5759-69. PubMed ID: 20597487
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, crystal structure and antiproliferative mechanisms of 2-acetylpyridine-thiosemicarbazones Ga(III) with a greater selectivity against tumor cells.
    Qi J; Zheng Y; Qian K; Tian L; Zhang GX; Cheng Z; Wang Y
    J Inorg Biochem; 2017 Dec; 177():110-117. PubMed ID: 28946027
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation.
    Kowol CR; Trondl R; Heffeter P; Arion VB; Jakupec MA; Roller A; Galanski MS; Berger W; Keppler BK
    J Med Chem; 2009 Aug; 52(16):5032-43. PubMed ID: 19637923
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N(4)-tolyl-2-acetylpyridine thiosemicarbazones and their platinum(II,IV) and gold(III) complexes: cytotoxicity against human glioma cells and studies on the mode of action.
    Ferraz KS; Da Silva JG; Costa FM; Mendes BM; Rodrigues BL; dos Santos RG; Beraldo H
    Biometals; 2013 Oct; 26(5):677-91. PubMed ID: 23749148
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cationic and Neutral N-Heterocyclic Carbene Gold(I) Complexes: Cytotoxicity, NCI-60 Screening, Cellular Uptake, Inhibition of Mammalian Thioredoxin Reductase, and Reactive Oxygen Species Formation.
    Zhang C; Hemmert C; Gornitzka H; Cuvillier O; Zhang M; Sun RW
    ChemMedChem; 2018 Jun; 13(12):1218-1229. PubMed ID: 29603648
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 2-Acetylpyridine thiosemicarbazones are potent iron chelators and antiproliferative agents: redox activity, iron complexation and characterization of their antitumor activity.
    Richardson DR; Kalinowski DS; Richardson V; Sharpe PC; Lovejoy DB; Islam M; Bernhardt PV
    J Med Chem; 2009 Mar; 52(5):1459-70. PubMed ID: 19216562
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparative study of the antitumoral activity of phosphine-thiosemicarbazone gold(I) complexes obtained by different methodologies.
    González-Barcia LM; Fernández-Fariña S; Rodríguez-Silva L; Bermejo MR; González-Noya AM; Pedrido R
    J Inorg Biochem; 2020 Feb; 203():110931. PubMed ID: 31786438
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gold(I) NHC Complexes: Antiproliferative Activity, Cellular Uptake, Inhibition of Mammalian and Bacterial Thioredoxin Reductases, and Gram-Positive Directed Antibacterial Effects.
    Schmidt C; Karge B; Misgeld R; Prokop A; Franke R; Brönstrup M; Ott I
    Chemistry; 2017 Feb; 23(8):1869-1880. PubMed ID: 27865002
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gold(I) and Gold(III) N-Heterocyclic Carbene Complexes as Antibacterial Agents and Inhibitors of Bacterial Thioredoxin Reductase.
    Büssing R; Karge B; Lippmann P; Jones PG; Brönstrup M; Ott I
    ChemMedChem; 2021 Nov; 16(22):3402-3409. PubMed ID: 34268875
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Triapine Derivatives Act as Copper Delivery Vehicles to Induce Deadly Metal Overload in Cancer Cells.
    Ohui K; Stepanenko I; Besleaga I; Babak MV; Stafi R; Darvasiova D; Giester G; Pósa V; Enyedy EA; Vegh D; Rapta P; Ang WH; Popović-Bijelić A; Arion VB
    Biomolecules; 2020 Sep; 10(9):. PubMed ID: 32961653
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Applying the designed multiple ligands approach to inhibit dihydrofolate reductase and thioredoxin reductase for anti-proliferative activity.
    Ng HL; Chen S; Chew EH; Chui WK
    Eur J Med Chem; 2016 Jun; 115():63-74. PubMed ID: 26994844
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.