154 related articles for article (PubMed ID: 2709380)
1. Synthesis of 5-[1-hydroxy(or methoxy)-2-bromo(or chloro)ethyl]-2'-deoxyuridines and related halohydrin analogues with antiviral and cytotoxic activity.
Kumar R; Wiebe LI; Hall TW; Knaus EE; Tovell DR; Tyrrell DL; Allen TM; Fathi-Afshar R
J Med Chem; 1989 May; 32(5):941-4. PubMed ID: 2709380
[TBL] [Abstract][Full Text] [Related]
2. Synthesis, antiviral and cytotoxic activity of 2'-deoxyuridines, 2'-fluoro-2'-deoxyuridines and 2'-arabinouridines containing 5-(1-hydroxy-2-halo-2-ethoxycarbonylethyl)-, 5-(1-hydroxy-2-iodo-2- carboxyethyl)- and 5-[1-hydroxy (or methoxy)-2-iodoethyl] substituents.
Kumar R; Wiebe LI; Knaus EE; Allen TM; Tempest ML
Drug Des Discov; 1992 Feb; 8(3):179-89. PubMed ID: 1326340
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and antiviral and cytotoxic activity of iodohydrin and iodomethoxy derivatives of 5-vinyl-2'-deoxyuridines, 2'-fluoro-2'-deoxyuridine, and uridine.
Kumar R; Xu LH; Knaus EE; Wiebe LI; Tovell DR; Tyrrell DL; Allen TM
J Med Chem; 1990 Feb; 33(2):717-23. PubMed ID: 2299637
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of 5-[1-hydroxy (or methoxy)-2,2-dihaloethyl]-2'- deoxyuridines with antiviral and cytotoxic activity.
Kumar R; Knaus EE; Wiebe LF; Allen TM
Antiviral Res; 1994 Aug; 24(4):315-25. PubMed ID: 7993076
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and antiviral activity of novel 5-(1-cyanamido-2-haloethyl) and 5-(1-hydroxy(or methoxy)-2-azidoethyl) analogues of uracil nucleosides.
Kumar R; Rai D; Sharma SK; Saffran HA; Blush R; Tyrrell DL
J Med Chem; 2001 Oct; 44(21):3531-8. PubMed ID: 11585457
[TBL] [Abstract][Full Text] [Related]
6. Synthesis, cytotoxic and antiviral activity of uracils containing 5-(1-hydroxy-2-haloethyl)- and 5-(1-methoxy-2-haloethyl) substituents.
Kumar R; Wiebe LI; Knaus EE; Allen TM; Fathi-Afshar R; Tovell DR; Tyrrell DL
Drug Des Deliv; 1989 May; 4(3):227-35. PubMed ID: 2490275
[TBL] [Abstract][Full Text] [Related]
7. Synthesis of the diastereomers of 5-(2,2-dichlorocyclopropyl)- and 5-(2-chlorocyclopropyl)-2'-deoxyuridine, and the antiviral and cytotoxic activity of these and bromo analogues.
Tandon M; Singh S; Wiebe LI; Knaus EE; Gati WP; Tempest ML
Drug Des Deliv; 1991 Jul; 7(4):295-307. PubMed ID: 1657019
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and antiviral activity of novel 5-(1-azido-2-haloethyl) and 5-(1-azido-, amino-, or methoxyethyl) analogs of 2'-deoxyuridine.
Kumar R; Wiebe LI; Knaus EE
J Med Chem; 1993 Aug; 36(17):2470-4. PubMed ID: 8394933
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and antiviral activity of 5-ethyl-5-halo-6-alkoxy-(or azido)-5,6-dihydro-2'-deoxyuridine diastereomers as potential prodrugs to 5-ethyl-2'-deoxyuridine.
Kumar R; Wiebe LI; Knaus EE
Arch Pharm (Weinheim); 1997 Aug; 330(8):259-63. PubMed ID: 9361522
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and antiviral properties of 5-(2-substituted vinyl)-6-aza-2'-deoxyuridines.
Mitchell WL; Ravenscroft P; Hill ML; Knutsen LJ; Judkins BD; Newton RF; Scopes DI
J Med Chem; 1986 May; 29(5):809-16. PubMed ID: 3009815
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters.
Béres J; Sági G; Bentrude WG; Balzarini J; De Clercq E; Otvös L
J Med Chem; 1986 Jul; 29(7):1243-9. PubMed ID: 3027328
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of 3'- and 5'-nitrooxy pyrimidine nucleoside nitrate esters: "nitric oxide donor" agents for evaluation as anticancer and antiviral agents.
Naimi E; Zhou A; Khalili P; Wiebe LI; Balzarini J; De Clercq E; Knaus EE
J Med Chem; 2003 Mar; 46(6):995-1004. PubMed ID: 12620076
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and antiviral activity of 5-heteroaryl-substituted 2'-deoxyuridines.
Wigerinck P; Snoeck R; Claes P; De Clercq E; Herdewijn P
J Med Chem; 1991 Jun; 34(6):1767-72. PubMed ID: 2061920
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and enzymatic transformations of 5-halo-6-methoxy-5,6-dihydro derivatives of 5-[1-methoxy-2-halo (or 2,2-dihalo)ethyl]-2'-deoxyuridines as potential herpes simplex virus inhibitors.
Kumar R
J Enzyme Inhib Med Chem; 2003 Jun; 18(3):273-8. PubMed ID: 14506919
[TBL] [Abstract][Full Text] [Related]
15. Synthesis of 5-isoxazol-5-yl-2'-deoxyuridines exhibiting antiviral activity against HSV and several RNA viruses.
Lee YS; Park SM; Kim BH
Bioorg Med Chem Lett; 2009 Feb; 19(4):1126-8. PubMed ID: 19147352
[TBL] [Abstract][Full Text] [Related]
16. Uracil derivatives. V. Syntheses and growth-inhibitory activity against L-1210 cells of 5-substituted 2'-deoxyuridines and orotidine derivatives.
Okada J; Nakano K; Miyake H
Chem Pharm Bull (Tokyo); 1985 Feb; 33(2):856-64. PubMed ID: 4017129
[No Abstract] [Full Text] [Related]
17. 5-Bromo (or chloro)-6-azido-5,6-dihydro-2' -deoxyuridine and -thymidine derivatives with potent antiviral activity.
Kumar R
Bioorg Med Chem Lett; 2002 Feb; 12(3):275-8. PubMed ID: 11814776
[TBL] [Abstract][Full Text] [Related]
18. Synthesis, biotransformation, pharmacokinetics, and antiviral properties of 5-ethyl-5-halo-6-methoxy-5,6-dihydro-2'-deoxyuridine diastereomers.
Cheraghali AM; Kumar R; Wang L; Knaus EE; Wiebe LI
Biochem Pharmacol; 1994 Apr; 47(9):1615-25. PubMed ID: 8185676
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and antiviral activity of 5-thien-2-yl-2'-deoxyuridine analogues.
Wigerinck P; Kerremans L; Claes P; Snoeck R; Maudgal P; De Clercq E; Herdewijn P
J Med Chem; 1993 Mar; 36(5):538-43. PubMed ID: 8388474
[TBL] [Abstract][Full Text] [Related]
20. [Synthesis of anomeric 5-trimethylgermyl-2'-deoxyuridines and study of their antiviral and cytotoxic properties].
Mel'nik SIa; Bakhmedova AA; Nedorezova TP; Iartseva IV; Zhukova OS
Bioorg Khim; 1985 Sep; 11(9):1248-52. PubMed ID: 2998405
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
