1415 related articles for article (PubMed ID: 27097283)
1. C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Dafinca R; Scaber J; Ababneh N; Lalic T; Weir G; Christian H; Vowles J; Douglas AG; Fletcher-Jones A; Browne C; Nakanishi M; Turner MR; Wade-Martins R; Cowley SA; Talbot K
Stem Cells; 2016 Aug; 34(8):2063-78. PubMed ID: 27097283
[TBL] [Abstract][Full Text] [Related]
2. Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repair.
Ababneh NA; Scaber J; Flynn R; Douglas A; Barbagallo P; Candalija A; Turner MR; Sims D; Dafinca R; Cowley SA; Talbot K
Hum Mol Genet; 2020 Aug; 29(13):2200-2217. PubMed ID: 32504093
[TBL] [Abstract][Full Text] [Related]
3. C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels.
Beckers J; Tharkeshwar AK; Van Damme P
Autophagy; 2021 Nov; 17(11):3306-3322. PubMed ID: 33632058
[TBL] [Abstract][Full Text] [Related]
4. Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion.
Sareen D; O'Rourke JG; Meera P; Muhammad AK; Grant S; Simpkinson M; Bell S; Carmona S; Ornelas L; Sahabian A; Gendron T; Petrucelli L; Baughn M; Ravits J; Harms MB; Rigo F; Bennett CF; Otis TS; Svendsen CN; Baloh RH
Sci Transl Med; 2013 Oct; 5(208):208ra149. PubMed ID: 24154603
[TBL] [Abstract][Full Text] [Related]
5. Disruption of ER-mitochondria tethering and signalling in C9orf72-associated amyotrophic lateral sclerosis and frontotemporal dementia.
Gomez-Suaga P; Mórotz GM; Markovinovic A; Martín-Guerrero SM; Preza E; Arias N; Mayl K; Aabdien A; Gesheva V; Nishimura A; Annibali A; Lee Y; Mitchell JC; Wray S; Shaw C; Noble W; Miller CCJ
Aging Cell; 2022 Feb; 21(2):e13549. PubMed ID: 35026048
[TBL] [Abstract][Full Text] [Related]
6. Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons.
Almeida S; Gascon E; Tran H; Chou HJ; Gendron TF; Degroot S; Tapper AR; Sellier C; Charlet-Berguerand N; Karydas A; Seeley WW; Boxer AL; Petrucelli L; Miller BL; Gao FB
Acta Neuropathol; 2013 Sep; 126(3):385-99. PubMed ID: 23836290
[TBL] [Abstract][Full Text] [Related]
7. Impairment of Mitochondrial Calcium Buffering Links Mutations in C9ORF72 and TARDBP in iPS-Derived Motor Neurons from Patients with ALS/FTD.
Dafinca R; Barbagallo P; Farrimond L; Candalija A; Scaber J; Ababneh NA; Sathyaprakash C; Vowles J; Cowley SA; Talbot K
Stem Cell Reports; 2020 May; 14(5):892-908. PubMed ID: 32330447
[TBL] [Abstract][Full Text] [Related]
8. The clinical and pathological phenotype of C9ORF72 hexanucleotide repeat expansions.
Simón-Sánchez J; Dopper EG; Cohn-Hokke PE; Hukema RK; Nicolaou N; Seelaar H; de Graaf JR; de Koning I; van Schoor NM; Deeg DJ; Smits M; Raaphorst J; van den Berg LH; Schelhaas HJ; De Die-Smulders CE; Majoor-Krakauer D; Rozemuller AJ; Willemsen R; Pijnenburg YA; Heutink P; van Swieten JC
Brain; 2012 Mar; 135(Pt 3):723-35. PubMed ID: 22300876
[TBL] [Abstract][Full Text] [Related]
9. Knocking out C9ORF72 Exacerbates Axonal Trafficking Defects Associated with Hexanucleotide Repeat Expansion and Reduces Levels of Heat Shock Proteins.
Abo-Rady M; Kalmbach N; Pal A; Schludi C; Janosch A; Richter T; Freitag P; Bickle M; Kahlert AK; Petri S; Stefanov S; Glass H; Staege S; Just W; Bhatnagar R; Edbauer D; Hermann A; Wegner F; Sterneckert JL
Stem Cell Reports; 2020 Mar; 14(3):390-405. PubMed ID: 32084385
[TBL] [Abstract][Full Text] [Related]
10. The DNA damage response (DDR) is induced by the C9orf72 repeat expansion in amyotrophic lateral sclerosis.
Farg MA; Konopka A; Soo KY; Ito D; Atkin JD
Hum Mol Genet; 2017 Aug; 26(15):2882-2896. PubMed ID: 28481984
[TBL] [Abstract][Full Text] [Related]
11. RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3.
Ramesh N; Daley EL; Gleixner AM; Mann JR; Kour S; Mawrie D; Anderson EN; Kofler J; Donnelly CJ; Kiskinis E; Pandey UB
Acta Neuropathol Commun; 2020 Oct; 8(1):177. PubMed ID: 33129345
[TBL] [Abstract][Full Text] [Related]
12. A C9ORF72 BAC mouse model recapitulates key epigenetic perturbations of ALS/FTD.
Esanov R; Cabrera GT; Andrade NS; Gendron TF; Brown RH; Benatar M; Wahlestedt C; Mueller C; Zeier Z
Mol Neurodegener; 2017 Jun; 12(1):46. PubMed ID: 28606110
[TBL] [Abstract][Full Text] [Related]
13. C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia.
Aoki Y; Manzano R; Lee Y; Dafinca R; Aoki M; Douglas AGL; Varela MA; Sathyaprakash C; Scaber J; Barbagallo P; Vader P; Mäger I; Ezzat K; Turner MR; Ito N; Gasco S; Ohbayashi N; El Andaloussi S; Takeda S; Fukuda M; Talbot K; Wood MJA
Brain; 2017 Apr; 140(4):887-897. PubMed ID: 28334866
[TBL] [Abstract][Full Text] [Related]
14. UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Zhang K; Wang A; Zhong K; Qi S; Wei C; Shu X; Tu WY; Xu W; Xia C; Xiao Y; Chen A; Bai L; Zhang J; Luo B; Wang W; Shen C
Neuron; 2021 Jun; 109(12):1949-1962.e6. PubMed ID: 33991504
[TBL] [Abstract][Full Text] [Related]
15. Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons.
Lopez-Gonzalez R; Lu Y; Gendron TF; Karydas A; Tran H; Yang D; Petrucelli L; Miller BL; Almeida S; Gao FB
Neuron; 2016 Oct; 92(2):383-391. PubMed ID: 27720481
[TBL] [Abstract][Full Text] [Related]
16. ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD.
Moore S; Alsop E; Lorenzini I; Starr A; Rabichow BE; Mendez E; Levy JL; Burciu C; Reiman R; Chew J; Belzil VV; W Dickson D; Robertson J; Staats KA; Ichida JK; Petrucelli L; Van Keuren-Jensen K; Sattler R
Acta Neuropathol; 2019 Jul; 138(1):49-65. PubMed ID: 30945056
[TBL] [Abstract][Full Text] [Related]
17. Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction.
Perkins EM; Burr K; Banerjee P; Mehta AR; Dando O; Selvaraj BT; Suminaite D; Nanda J; Henstridge CM; Gillingwater TH; Hardingham GE; Wyllie DJA; Chandran S; Livesey MR
Mol Neurodegener; 2021 Mar; 16(1):13. PubMed ID: 33663561
[TBL] [Abstract][Full Text] [Related]
18. Circadian sleep/wake-associated cells show dipeptide repeat protein aggregates in C9orf72-related ALS and FTLD cases.
Dedeene L; Van Schoor E; Vandenberghe R; Van Damme P; Poesen K; Thal DR
Acta Neuropathol Commun; 2019 Dec; 7(1):189. PubMed ID: 31791419
[TBL] [Abstract][Full Text] [Related]
19. Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice.
Peters OM; Cabrera GT; Tran H; Gendron TF; McKeon JE; Metterville J; Weiss A; Wightman N; Salameh J; Kim J; Sun H; Boylan KB; Dickson D; Kennedy Z; Lin Z; Zhang YJ; Daughrity L; Jung C; Gao FB; Sapp PC; Horvitz HR; Bosco DA; Brown SP; de Jong P; Petrucelli L; Mueller C; Brown RH
Neuron; 2015 Dec; 88(5):902-909. PubMed ID: 26637797
[TBL] [Abstract][Full Text] [Related]
20. Generation of a human induced pluripotent stem cell (iPSC) line (IBMS-iPSC-048-05) from a patient with ALS and parkinsonism having a hexanucleotide repeat expansion mutation in C9orf72 gene.
Lin HY; Tsai LK; Cheng YC; Lu HE; Huang CY; Hsieh PCH; Lin CH
Stem Cell Res; 2020 Apr; 44():101734. PubMed ID: 32151952
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
