BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

657 related articles for article (PubMed ID: 27098609)

  • 1. Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.
    Tang Y; Wallace M; Sanchez-Gurmaches J; Hsiao WY; Li H; Lee PL; Vernia S; Metallo CM; Guertin DA
    Nat Commun; 2016 Apr; 7():11365. PubMed ID: 27098609
    [TBL] [Abstract][Full Text] [Related]  

  • 2. AMPD1 regulates mTORC1-p70 S6 kinase axis in the control of insulin sensitivity in skeletal muscle.
    Tandelilin AA; Hirase T; Hudoyo AW; Cheng J; Toyama K; Morisaki H; Morisaki T
    BMC Endocr Disord; 2015 Mar; 15():11. PubMed ID: 25887856
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in mice.
    Jois T; Chen W; Howard V; Harvey R; Youngs K; Thalmann C; Saha P; Chan L; Cowley MA; Sleeman MW
    Mol Metab; 2017 Nov; 6(11):1381-1394. PubMed ID: 29107286
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Down regulation of Peroxiredoxin-3 in 3T3-L1 adipocytes leads to oxidation of Rictor in the mammalian-target of rapamycin complex 2 (mTORC2).
    Olson DH; Burrill JS; Kuzmicic J; Hahn WS; Park JM; Kim DH; Bernlohr DA
    Biochem Biophys Res Commun; 2017 Nov; 493(3):1311-1317. PubMed ID: 28986255
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide.
    Festuccia WT; Pouliot P; Bakan I; Sabatini DM; Laplante M
    PLoS One; 2014; 9(4):e95432. PubMed ID: 24740015
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease.
    Hung CM; Calejman CM; Sanchez-Gurmaches J; Li H; Clish CB; Hettmer S; Wagers AJ; Guertin DA
    Cell Rep; 2014 Jul; 8(1):256-71. PubMed ID: 25001283
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis.
    Sanchez-Gurmaches J; Tang Y; Jespersen NZ; Wallace M; Martinez Calejman C; Gujja S; Li H; Edwards YJK; Wolfrum C; Metallo CM; Nielsen S; Scheele C; Guertin DA
    Cell Metab; 2018 Jan; 27(1):195-209.e6. PubMed ID: 29153407
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Liver clock protein BMAL1 promotes de novo lipogenesis through insulin-mTORC2-AKT signaling.
    Zhang D; Tong X; Arthurs B; Guha A; Rui L; Kamath A; Inoki K; Yin L
    J Biol Chem; 2014 Sep; 289(37):25925-35. PubMed ID: 25063808
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepatic cis-vaccenic acid synthesis in diet-induced obese mice.
    Tripathy S; Jump DB
    J Lipid Res; 2013 Jan; 54(1):71-84. PubMed ID: 23099444
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity.
    Lamming DW; Ye L; Katajisto P; Goncalves MD; Saitoh M; Stevens DM; Davis JG; Salmon AB; Richardson A; Ahima RS; Guertin DA; Sabatini DM; Baur JA
    Science; 2012 Mar; 335(6076):1638-43. PubMed ID: 22461615
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism.
    Herman MA; Peroni OD; Villoria J; Schön MR; Abumrad NA; Blüher M; Klein S; Kahn BB
    Nature; 2012 Apr; 484(7394):333-8. PubMed ID: 22466288
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pu'erh tea extract-mediated protection against hepatosteatosis and insulin resistance in mice with diet-induced obesity is associated with the induction of de novo lipogenesis in visceral adipose tissue.
    Cai X; Hayashi S; Fang C; Hao S; Wang X; Nishiguchi S; Tsutsui H; Sheng J
    J Gastroenterol; 2017 Dec; 52(12):1240-1251. PubMed ID: 28364190
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.
    Hagiwara A; Cornu M; Cybulski N; Polak P; Betz C; Trapani F; Terracciano L; Heim MH; Rüegg MA; Hall MN
    Cell Metab; 2012 May; 15(5):725-38. PubMed ID: 22521878
    [TBL] [Abstract][Full Text] [Related]  

  • 14. mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
    Le Bacquer O; Queniat G; Gmyr V; Kerr-Conte J; Lefebvre B; Pattou F
    J Endocrinol; 2013 Jan; 216(1):21-9. PubMed ID: 23092880
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
    Woo SY; Kim DH; Jun CB; Kim YM; Haar EV; Lee SI; Hegg JW; Bandhakavi S; Griffin TJ; Kim DH
    J Biol Chem; 2007 Aug; 282(35):25604-12. PubMed ID: 17599906
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fibroblast growth factor 1 ameliorates adipose tissue inflammation and systemic insulin resistance via enhancing adipocyte mTORC2/Rictor signal.
    Zhao L; Fan M; Zhao L; Yun H; Yang Y; Wang C; Qin D
    J Cell Mol Med; 2020 Nov; 24(21):12813-12825. PubMed ID: 32979037
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition.
    Singh BK; Sinha RA; Zhou J; Tripathi M; Ohba K; Wang ME; Astapova I; Ghosh S; Hollenberg AN; Gauthier K; Yen PM
    J Biol Chem; 2016 Jan; 291(1):198-214. PubMed ID: 26453307
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting hepatic pyruvate dehydrogenase kinases restores insulin signaling and mitigates ChREBP-mediated lipogenesis in diet-induced obese mice.
    Wu CY; Tso SC; Chuang JL; Gui WJ; Lou M; Sharma G; Khemtong C; Qi X; Wynn RM; Chuang DT
    Mol Metab; 2018 Jun; 12():12-24. PubMed ID: 29656110
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The GATOR2-mTORC2 axis mediates Sestrin2-induced AKT Ser/Thr kinase activation.
    Kowalsky AH; Namkoong S; Mettetal E; Park HW; Kazyken D; Fingar DC; Lee JH
    J Biol Chem; 2020 Feb; 295(7):1769-1780. PubMed ID: 31915252
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rictor in perivascular adipose tissue controls vascular function by regulating inflammatory molecule expression.
    Bhattacharya I; Drägert K; Albert V; Contassot E; Damjanovic M; Hagiwara A; Zimmerli L; Humar R; Hall MN; Battegay EJ; Haas E
    Arterioscler Thromb Vasc Biol; 2013 Sep; 33(9):2105-11. PubMed ID: 23868942
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.