202 related articles for article (PubMed ID: 27104806)
1. Tissue expression profile of human neonatal Fc receptor (FcRn) in Tg32 transgenic mice.
Fan YY; Avery LB; Wang M; O'Hara DM; Leung S; Neubert H
MAbs; 2016 Jul; 8(5):848-53. PubMed ID: 27104806
[TBL] [Abstract][Full Text] [Related]
2. Quantitative Analysis of Human Neonatal Fc Receptor (FcRn) Tissue Expression in Transgenic Mice by Online Peptide Immuno-Affinity LC-HRMS.
Fan YY; Neubert H
Anal Chem; 2016 Apr; 88(8):4239-47. PubMed ID: 27012525
[TBL] [Abstract][Full Text] [Related]
3. Distribution of FcRn Across Species and Tissues.
Latvala S; Jacobsen B; Otteneder MB; Herrmann A; Kronenberg S
J Histochem Cytochem; 2017 Jun; 65(6):321-333. PubMed ID: 28402755
[TBL] [Abstract][Full Text] [Related]
4. Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies.
Avery LB; Wang M; Kavosi MS; Joyce A; Kurz JC; Fan YY; Dowty ME; Zhang M; Zhang Y; Cheng A; Hua F; Jones HM; Neubert H; Polzer RJ; O'Hara DM
MAbs; 2016; 8(6):1064-78. PubMed ID: 27232760
[TBL] [Abstract][Full Text] [Related]
5. Human FcRn Tissue Expression Profile and Half-Life in PBMCs.
Fan YY; Farrokhi V; Caiazzo T; Wang M; O'Hara DM; Neubert H
Biomolecules; 2019 Aug; 9(8):. PubMed ID: 31443181
[TBL] [Abstract][Full Text] [Related]
6. Correlations between pharmacokinetics of IgG antibodies in primates vs. FcRn-transgenic mice reveal a rodent model with predictive capabilities.
Tam SH; McCarthy SG; Brosnan K; Goldberg KM; Scallon BJ
MAbs; 2013; 5(3):397-405. PubMed ID: 23549129
[TBL] [Abstract][Full Text] [Related]
7. Quantification of Neonatal Fc Receptor and Beta-2 Microglobulin in Human Liver Tissues by Ultraperformance Liquid Chromatography-Multiple Reaction Monitoring-based Targeted Quantitative Proteomics for Applications in Biotherapeutic Physiologically-based Pharmacokinetic Models.
Qiu X; Wang MZ
Drug Metab Dispos; 2020 Oct; 48(10):925-933. PubMed ID: 32723849
[TBL] [Abstract][Full Text] [Related]
8. Pharmacokinetics of novel Fc-engineered monoclonal and multispecific antibodies in cynomolgus monkeys and humanized FcRn transgenic mouse models.
Valente D; Mauriac C; Schmidt T; Focken I; Beninga J; Mackness B; Qiu H; Vicat P; Kandira A; Radošević K; Rao S; Darbyshire J; Kabiri M
MAbs; 2020; 12(1):1829337. PubMed ID: 33079615
[TBL] [Abstract][Full Text] [Related]
9. Linear pharmacokinetic parameters for monoclonal antibodies are similar within a species and across different pharmacological targets: A comparison between human, cynomolgus monkey and hFcRn Tg32 transgenic mouse using a population-modeling approach.
Betts A; Keunecke A; van Steeg TJ; van der Graaf PH; Avery LB; Jones H; Berkhout J
MAbs; 2018 Jul; 10(5):751-764. PubMed ID: 29634430
[TBL] [Abstract][Full Text] [Related]
10. Humanized FcRn mouse models for evaluating pharmacokinetics of human IgG antibodies.
Proetzel G; Roopenian DC
Methods; 2014 Jan; 65(1):148-53. PubMed ID: 23867339
[TBL] [Abstract][Full Text] [Related]
11. Contribution of FcRn binding to intestinal uptake of IgG in suckling rat pups and human FcRn-transgenic mice.
Kliwinski C; Cooper PR; Perkinson R; Mabus JR; Tam SH; Wilkinson TM; Giles-Komar J; Scallon B; Powers GD; Hornby PJ
Am J Physiol Gastrointest Liver Physiol; 2013 Feb; 304(3):G262-70. PubMed ID: 23220220
[TBL] [Abstract][Full Text] [Related]
12. A novel approach to investigate the effect of methionine oxidation on pharmacokinetic properties of therapeutic antibodies.
Stracke J; Emrich T; Rueger P; Schlothauer T; Kling L; Knaupp A; Hertenberger H; Wolfert A; Spick C; Lau W; Drabner G; Reiff U; Koll H; Papadimitriou A
MAbs; 2014; 6(5):1229-42. PubMed ID: 25517308
[TBL] [Abstract][Full Text] [Related]
13. The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity.
Abdiche YN; Yeung YA; Chaparro-Riggers J; Barman I; Strop P; Chin SM; Pham A; Bolton G; McDonough D; Lindquist K; Pons J; Rajpal A
MAbs; 2015; 7(2):331-43. PubMed ID: 25658443
[TBL] [Abstract][Full Text] [Related]
14. Application of human FcRn transgenic mice as a pharmacokinetic screening tool of monoclonal antibody.
Haraya K; Tachibana T; Nanami M; Ishigai M
Xenobiotica; 2014 Dec; 44(12):1127-34. PubMed ID: 25030041
[TBL] [Abstract][Full Text] [Related]
15. A Minimal Physiologically Based Pharmacokinetic Model with a Nested Endosome Compartment for Novel Engineered Antibodies.
Yuan D; Rode F; Cao Y
AAPS J; 2018 Mar; 20(3):48. PubMed ID: 29541870
[TBL] [Abstract][Full Text] [Related]
16. Analytical FcRn affinity chromatography for functional characterization of monoclonal antibodies.
Schlothauer T; Rueger P; Stracke JO; Hertenberger H; Fingas F; Kling L; Emrich T; Drabner G; Seeber S; Auer J; Koch S; Papadimitriou A
MAbs; 2013; 5(4):576-86. PubMed ID: 23765230
[TBL] [Abstract][Full Text] [Related]
17. Physiologically-based pharmacokinetic (PBPK) model to predict IgG tissue kinetics in wild-type and FcRn-knockout mice.
Garg A; Balthasar JP
J Pharmacokinet Pharmacodyn; 2007 Oct; 34(5):687-709. PubMed ID: 17636457
[TBL] [Abstract][Full Text] [Related]
18. Cellular recycling-driven in vivo half-life extension using recombinant albumin fusions tuned for neonatal Fc receptor (FcRn) engagement.
Larsen MT; Rawsthorne H; Schelde KK; Dagnæs-Hansen F; Cameron J; Howard KA
J Control Release; 2018 Oct; 287():132-141. PubMed ID: 30016735
[TBL] [Abstract][Full Text] [Related]
19. A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life.
Souders CA; Nelson SC; Wang Y; Crowley AR; Klempner MS; Thomas W
MAbs; 2015; 7(5):912-21. PubMed ID: 26018774
[TBL] [Abstract][Full Text] [Related]
20. Functional humanization of immunoglobulin heavy constant gamma 1 Fc domain human
Low BE; Christianson GJ; Lowell E; Qin W; Wiles MV
MAbs; 2020; 12(1):1829334. PubMed ID: 33025844
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
