319 related articles for article (PubMed ID: 27111510)
1. Extra-helical binding site of a glucagon receptor antagonist.
Jazayeri A; Doré AS; Lamb D; Krishnamurthy H; Southall SM; Baig AH; Bortolato A; Koglin M; Robertson NJ; Errey JC; Andrews SP; Teobald I; Brown AJ; Cooke RM; Weir M; Marshall FH
Nature; 2016 May; 533(7602):274-7. PubMed ID: 27111510
[TBL] [Abstract][Full Text] [Related]
2. Rearrangement of a polar core provides a conserved mechanism for constitutive activation of class B G protein-coupled receptors.
Yin Y; de Waal PW; He Y; Zhao LH; Yang D; Cai X; Jiang Y; Melcher K; Wang MW; Xu HE
J Biol Chem; 2017 Jun; 292(24):9865-9881. PubMed ID: 28356352
[TBL] [Abstract][Full Text] [Related]
3. Structure of the human glucagon class B G-protein-coupled receptor.
Siu FY; He M; de Graaf C; Han GW; Yang D; Zhang Z; Zhou C; Xu Q; Wacker D; Joseph JS; Liu W; Lau J; Cherezov V; Katritch V; Wang MW; Stevens RC
Nature; 2013 Jul; 499(7459):444-9. PubMed ID: 23863937
[TBL] [Abstract][Full Text] [Related]
4. Computational identification of novel natural inhibitors of glucagon receptor for checking type II diabetes mellitus.
Grover S; Dhanjal JK; Goyal S; Grover A; Sundar D
BMC Bioinformatics; 2014; 15 Suppl 16(Suppl 16):S13. PubMed ID: 25521597
[TBL] [Abstract][Full Text] [Related]
5. Structure of the glucagon receptor in complex with a glucagon analogue.
Zhang H; Qiao A; Yang L; Van Eps N; Frederiksen KS; Yang D; Dai A; Cai X; Zhang H; Yi C; Cao C; He L; Yang H; Lau J; Ernst OP; Hanson MA; Stevens RC; Wang MW; Reedtz-Runge S; Jiang H; Zhao Q; Wu B
Nature; 2018 Jan; 553(7686):106-110. PubMed ID: 29300013
[TBL] [Abstract][Full Text] [Related]
6. Paralog-divergent Features May Help Reduce Off-target Effects of Drugs: Hints from Glucagon Subfamily Analysis.
Sa Z; Zhou J; Zou Y; Su Z; Gu X
Genomics Proteomics Bioinformatics; 2017 Aug; 15(4):246-254. PubMed ID: 28642113
[TBL] [Abstract][Full Text] [Related]
7. Structure of the full-length glucagon class B G-protein-coupled receptor.
Zhang H; Qiao A; Yang D; Yang L; Dai A; de Graaf C; Reedtz-Runge S; Dharmarajan V; Zhang H; Han GW; Grant TD; Sierra RG; Weierstall U; Nelson G; Liu W; Wu Y; Ma L; Cai X; Lin G; Wu X; Geng Z; Dong Y; Song G; Griffin PR; Lau J; Cherezov V; Yang H; Hanson MA; Stevens RC; Zhao Q; Jiang H; Wang MW; Wu B
Nature; 2017 Jun; 546(7657):259-264. PubMed ID: 28514451
[TBL] [Abstract][Full Text] [Related]
8. Design and preparation of the class B G protein-coupled receptors GLP-1R and GCGR for
Wang H; Hu W; Liu D; Wüthrich K
FEBS J; 2021 Jul; 288(13):4053-4063. PubMed ID: 33369025
[TBL] [Abstract][Full Text] [Related]
9. Effect of hydrophobic and hydrogen bonding interactions on the potency of ß-alanine analogs of G-protein coupled glucagon receptor inhibitors.
Venugopal PP; Das BK; Soorya E; Chakraborty D
Proteins; 2020 Feb; 88(2):327-344. PubMed ID: 31443129
[TBL] [Abstract][Full Text] [Related]
10. Discovery of a novel glucagon receptor antagonist N-[(4-{(1S)-1-[3-(3, 5-dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl]ethyl}phenyl)carbonyl]-β-alanine (MK-0893) for the treatment of type II diabetes.
Xiong Y; Guo J; Candelore MR; Liang R; Miller C; Dallas-Yang Q; Jiang G; McCann PE; Qureshi SA; Tong X; Xu SS; Shang J; Vincent SH; Tota LM; Wright MJ; Yang X; Zhang BB; Tata JR; Parmee ER
J Med Chem; 2012 Jul; 55(13):6137-48. PubMed ID: 22708876
[TBL] [Abstract][Full Text] [Related]
11. Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-coupled Receptors.
Zhao LH; Yin Y; Yang D; Liu B; Hou L; Wang X; Pal K; Jiang Y; Feng Y; Cai X; Dai A; Liu M; Wang MW; Melcher K; Xu HE
J Biol Chem; 2016 Jul; 291(29):15119-30. PubMed ID: 27226600
[TBL] [Abstract][Full Text] [Related]
12. Inhibitory mechanism of an allosteric antibody targeting the glucagon receptor.
Mukund S; Shang Y; Clarke HJ; Madjidi A; Corn JE; Kates L; Kolumam G; Chiang V; Luis E; Murray J; Zhang Y; Hötzel I; Koth CM; Allan BB
J Biol Chem; 2013 Dec; 288(50):36168-78. PubMed ID: 24189067
[TBL] [Abstract][Full Text] [Related]
13. Conformational states of the full-length glucagon receptor.
Yang L; Yang D; de Graaf C; Moeller A; West GM; Dharmarajan V; Wang C; Siu FY; Song G; Reedtz-Runge S; Pascal BD; Wu B; Potter CS; Zhou H; Griffin PR; Carragher B; Yang H; Wang MW; Stevens RC; Jiang H
Nat Commun; 2015 Jul; 6():7859. PubMed ID: 26227798
[TBL] [Abstract][Full Text] [Related]
14. Activation and conformational dynamics of a class B G-protein-coupled glucagon receptor.
Li Y; Sun J; Li D; Lin J
Phys Chem Chem Phys; 2016 May; 18(18):12642-50. PubMed ID: 27094704
[TBL] [Abstract][Full Text] [Related]
15. Anti-diabetic efficacy and impact on amino acid metabolism of GRA1, a novel small-molecule glucagon receptor antagonist.
Mu J; Qureshi SA; Brady EJ; Muise ES; Candelore MR; Jiang G; Li Z; Wu MS; Yang X; Dallas-Yang Q; Miller C; Xiong Y; Langdon RB; Parmee ER; Zhang BB
PLoS One; 2012; 7(11):e49572. PubMed ID: 23185367
[TBL] [Abstract][Full Text] [Related]
16. Glucagon receptor antagonism induces increased cholesterol absorption.
Guan HP; Yang X; Lu K; Wang SP; Castro-Perez JM; Previs S; Wright M; Shah V; Herath K; Xie D; Szeto D; Forrest G; Xiao JC; Palyha O; Sun LP; Andryuk PJ; Engel SS; Xiong Y; Lin S; Kelley DE; Erion MD; Davis HR; Wang L
J Lipid Res; 2015 Nov; 56(11):2183-95. PubMed ID: 26373568
[TBL] [Abstract][Full Text] [Related]
17. Understanding Corticotropin Releasing Factor Receptor (CRFR) Activation Using Structural Models.
Cordomi A; Liapakis G; Matsoukas MT
Curr Mol Pharmacol; 2017; 10(4):325-333. PubMed ID: 28103783
[TBL] [Abstract][Full Text] [Related]
18. Expression, purification and preliminary characterization of glucagon receptor extracellular domain.
Wu L; Zhai Y; Lu J; Wang Q; Sun F
Protein Expr Purif; 2013 Jun; 89(2):232-40. PubMed ID: 23597780
[TBL] [Abstract][Full Text] [Related]
19. Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators.
Song G; Yang D; Wang Y; de Graaf C; Zhou Q; Jiang S; Liu K; Cai X; Dai A; Lin G; Liu D; Wu F; Wu Y; Zhao S; Ye L; Han GW; Lau J; Wu B; Hanson MA; Liu ZJ; Wang MW; Stevens RC
Nature; 2017 Jun; 546(7657):312-315. PubMed ID: 28514449
[TBL] [Abstract][Full Text] [Related]
20. Decoding Corticotropin-Releasing Factor Receptor Type 1 Crystal Structures.
Dore AS; Bortolato A; Hollenstein K; Cheng RKY; Read RJ; Marshall FH
Curr Mol Pharmacol; 2017; 10(4):334-344. PubMed ID: 28183242
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
