150 related articles for article (PubMed ID: 27112376)
1. ChAcNLS, a Novel Modification to Antibody-Conjugates Permitting Target Cell-Specific Endosomal Escape, Localization to the Nucleus, and Enhanced Total Intracellular Accumulation.
Beaudoin S; Rondeau A; Martel O; Bonin MA; van Lier JE; Leyton JV
Mol Pharm; 2016 Jun; 13(6):1915-26. PubMed ID: 27112376
[TBL] [Abstract][Full Text] [Related]
2. NLS-Cholic Acid Conjugation to IL-5Rα-Specific Antibody Improves Cellular Accumulation and In Vivo Tumor-Targeting Properties in a Bladder Cancer Model.
Paquette M; Beaudoin S; Tremblay MA; Jean S; Lopez AF; Lecomte R; Guérin B; Bentourkia M; Sabbagh R; Leyton JV
Bioconjug Chem; 2018 Apr; 29(4):1352-1363. PubMed ID: 29433309
[TBL] [Abstract][Full Text] [Related]
3. Auger electron radioimmunotherapeutic agent specific for the CD123+/CD131- phenotype of the leukemia stem cell population.
Leyton JV; Hu M; Gao C; Turner PV; Dick JE; Minden M; Reilly RM
J Nucl Med; 2011 Sep; 52(9):1465-73. PubMed ID: 21816968
[TBL] [Abstract][Full Text] [Related]
4. The human polynucleotide kinase/phosphatase (hPNKP) inhibitor A12B4C3 radiosensitizes human myeloid leukemia cells to Auger electron-emitting anti-CD123 ¹¹¹In-NLS-7G3 radioimmunoconjugates.
Zereshkian A; Leyton JV; Cai Z; Bergstrom D; Weinfeld M; Reilly RM
Nucl Med Biol; 2014; 41(5):377-83. PubMed ID: 24637100
[TBL] [Abstract][Full Text] [Related]
5. Characterization of a multifunctional PEG-based gene delivery system containing nuclear localization signals and endosomal escape peptides.
Moore NM; Sheppard CL; Sakiyama-Elbert SE
Acta Biomater; 2009 Mar; 5(3):854-64. PubMed ID: 18926782
[TBL] [Abstract][Full Text] [Related]
6. Light-Controlled Delivery of Monoclonal Antibodies for Targeted Photoinactivation of Ki-67.
Wang S; Hüttmann G; Zhang Z; Vogel A; Birngruber R; Tangutoori S; Hasan T; Rahmanzadeh R
Mol Pharm; 2015 Sep; 12(9):3272-81. PubMed ID: 26226545
[TBL] [Abstract][Full Text] [Related]
7. The mechanism of selective transfection mediated by pentablock copolymers; part II: nuclear entry and endosomal escape.
Zhang B; Mallapragada S
Acta Biomater; 2011 Apr; 7(4):1580-7. PubMed ID: 21115139
[TBL] [Abstract][Full Text] [Related]
8. Accum™ Technology: A Novel Conjugable Primer for Onco-Immunotherapy.
El-Kadiry AE; Beaudoin S; Plouffe S; Rafei M
Molecules; 2022 Jun; 27(12):. PubMed ID: 35744930
[TBL] [Abstract][Full Text] [Related]
9. Initial Evaluation of Antibody-conjugates Modified with Viral-derived Peptides for Increasing Cellular Accumulation and Improving Tumor Targeting.
Beaudoin S; Paquette M; Fafard-Couture L; Tremblay MA; Lecomte R; Guérin B; Leyton JV
J Vis Exp; 2018 Mar; (133):. PubMed ID: 29578523
[TBL] [Abstract][Full Text] [Related]
10. Endosomal escape efficiency of fusogenic B18 and B55 peptides fused with anti-EGFR single chain Fv as estimated by nuclear translocation.
Niikura K; Horisawa K; Doi N
J Biochem; 2016 Jan; 159(1):123-32. PubMed ID: 26338729
[TBL] [Abstract][Full Text] [Related]
11. Novel cell nucleus directed fluorescent tetraazacyclododecane-tetra-acetic acid compounds.
Sturzu A; Klose U; Echner H; Regenbogen M; Kalbacher H; Gharabaghi A; Heckl S
Med Chem; 2009 Jan; 5(1):93-102. PubMed ID: 19149655
[TBL] [Abstract][Full Text] [Related]
12. Efficient Subcellular Targeting to the Cell Nucleus of Quantum Dots Densely Decorated with a Nuclear Localization Sequence Peptide.
Maity AR; Stepensky D
ACS Appl Mater Interfaces; 2016 Jan; 8(3):2001-9. PubMed ID: 26731220
[TBL] [Abstract][Full Text] [Related]
13. Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody-drug conjugates.
Austin CD; Wen X; Gazzard L; Nelson C; Scheller RH; Scales SJ
Proc Natl Acad Sci U S A; 2005 Dec; 102(50):17987-92. PubMed ID: 16322102
[TBL] [Abstract][Full Text] [Related]
14. Chitosan Nanoparticles for Nuclear Targeting: The Effect of Nanoparticle Size and Nuclear Localization Sequence Density.
Tammam SN; Azzazy HM; Breitinger HG; Lamprecht A
Mol Pharm; 2015 Dec; 12(12):4277-89. PubMed ID: 26465978
[TBL] [Abstract][Full Text] [Related]
15. The influence of Pluronics nanovehicles on dark cytotoxicity, photocytotoxicity and localization of four model photosensitizers in cancer cells.
Sobczyński J; Kristensen S; Berg K
Photochem Photobiol Sci; 2014 Jan; 13(1):8-22. PubMed ID: 24158176
[TBL] [Abstract][Full Text] [Related]
16. Establishment of subcellular fractionation techniques to monitor the intracellular fate of polymer therapeutics I. Differential centrifugation fractionation B16F10 cells and use to study the intracellular fate of HPMA copolymer - doxorubicin.
Seib FP; Jones AT; Duncan R
J Drug Target; 2006 Jul; 14(6):375-90. PubMed ID: 17092838
[TBL] [Abstract][Full Text] [Related]
17. A biomimetic pH-responsive polymer directs endosomal release and intracellular delivery of an endocytosed antibody complex.
Lackey CA; Press OW; Hoffman AS; Stayton PS
Bioconjug Chem; 2002; 13(5):996-1001. PubMed ID: 12236781
[TBL] [Abstract][Full Text] [Related]
18. Intracellular regulation of macromolecules using pH-sensitive liposomes and nuclear localization signal: qualitative and quantitative evaluation of intracellular trafficking.
Tachibana R; Harashima H; Shono M; Azumano M; Niwa M; Futaki S; Kiwada H
Biochem Biophys Res Commun; 1998 Oct; 251(2):538-44. PubMed ID: 9792809
[TBL] [Abstract][Full Text] [Related]
19. Novel dual labelled nucleus-directed conjugates containing correct and mutant nuclear localisation sequences.
Sturzu A; Regenbogen M; Klose U; Echner H; Gharabaghi A; Heckl S
Eur J Pharm Sci; 2008 Mar; 33(3):207-16. PubMed ID: 18243673
[TBL] [Abstract][Full Text] [Related]
20. Monoclonal antibody-mediated targeting of CD123, IL-3 receptor alpha chain, eliminates human acute myeloid leukemic stem cells.
Jin L; Lee EM; Ramshaw HS; Busfield SJ; Peoppl AG; Wilkinson L; Guthridge MA; Thomas D; Barry EF; Boyd A; Gearing DP; Vairo G; Lopez AF; Dick JE; Lock RB
Cell Stem Cell; 2009 Jul; 5(1):31-42. PubMed ID: 19570512
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
