123 related articles for article (PubMed ID: 27112452)
1. Identification of small-molecule compounds targeting the dishevelled PDZ domain by virtual screening and binding studies.
Choi J; Ma S; Kim HY; Yun JH; Heo JN; Lee W; Choi KY; No KT
Bioorg Med Chem; 2016 Aug; 24(15):3259-66. PubMed ID: 27112452
[TBL] [Abstract][Full Text] [Related]
2. Discovery of a small-molecule inhibitor of Dvl-CXXC5 interaction by computational approaches.
Ma S; Choi J; Jin X; Kim HY; Yun JH; Lee W; Choi KY; No KT
J Comput Aided Mol Des; 2018 May; 32(5):643-655. PubMed ID: 29627878
[TBL] [Abstract][Full Text] [Related]
3. Synthesis of potent dishevelled PDZ domain inhibitors guided by virtual screening and NMR studies.
Shan J; Zhang X; Bao J; Cassell R; Zheng JJ
Chem Biol Drug Des; 2012 Apr; 79(4):376-83. PubMed ID: 22172211
[TBL] [Abstract][Full Text] [Related]
4. Crystal structure of the PDZ domain of mouse Dishevelled 1 and its interaction with CXXC5.
Lee I; Choi S; Yun JH; Seo SH; Choi S; Choi KY; Lee W
Biochem Biophys Res Commun; 2017 Apr; 485(3):584-590. PubMed ID: 27932247
[TBL] [Abstract][Full Text] [Related]
5. Autoinhibition of Dishevelled protein regulated by its extreme C terminus plays a distinct role in Wnt/β-catenin and Wnt/planar cell polarity (PCP) signaling pathways.
Qi J; Lee HJ; Saquet A; Cheng XN; Shao M; Zheng JJ; Shi DL
J Biol Chem; 2017 Apr; 292(14):5898-5908. PubMed ID: 28223363
[TBL] [Abstract][Full Text] [Related]
6. Identification of a specific inhibitor of the dishevelled PDZ domain.
Shan J; Shi DL; Wang J; Zheng J
Biochemistry; 2005 Nov; 44(47):15495-503. PubMed ID: 16300398
[TBL] [Abstract][Full Text] [Related]
7. Identification of tripeptides recognized by the PDZ domain of Dishevelled.
Lee HJ; Wang NX; Shao Y; Zheng JJ
Bioorg Med Chem; 2009 Feb; 17(4):1701-8. PubMed ID: 19157887
[TBL] [Abstract][Full Text] [Related]
8. Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay.
Gammons MV; Rutherford TJ; Steinhart Z; Angers S; Bienz M
J Cell Sci; 2016 Oct; 129(20):3892-3902. PubMed ID: 27744318
[TBL] [Abstract][Full Text] [Related]
9. Small molecule inhibitors of the Dishevelled-CXXC5 interaction are new drug candidates for bone anabolic osteoporosis therapy.
Kim HY; Choi S; Yoon JH; Lim HJ; Lee H; Choi J; Ro EJ; Heo JN; Lee W; No KT; Choi KY
EMBO Mol Med; 2016 Apr; 8(4):375-87. PubMed ID: 26941261
[TBL] [Abstract][Full Text] [Related]
10. Can We Pharmacologically Target Dishevelled: The Key Signal Transducer in the Wnt Pathways?
Micka M; Bryja V
Handb Exp Pharmacol; 2021; 269():117-135. PubMed ID: 34382124
[TBL] [Abstract][Full Text] [Related]
11. Simulations of a specific inhibitor of the dishevelled PDZ domain.
Chen X; Deng Y
J Mol Model; 2009 Jan; 15(1):91-6. PubMed ID: 18953581
[TBL] [Abstract][Full Text] [Related]
12. Discovery and characterization of a small molecule inhibitor of the PDZ domain of dishevelled.
Grandy D; Shan J; Zhang X; Rao S; Akunuru S; Li H; Zhang Y; Alpatov I; Zhang XA; Lang RA; Shi DL; Zheng JJ
J Biol Chem; 2009 Jun; 284(24):16256-16263. PubMed ID: 19383605
[TBL] [Abstract][Full Text] [Related]
13. Virtual ligand screening combined with NMR to identify Dvl PDZ domain inhibitors targeting the Wnt signaling.
Shan J; Zheng JJ
Methods Mol Biol; 2012; 928():17-28. PubMed ID: 22956130
[TBL] [Abstract][Full Text] [Related]
14. Characterization of function of three domains in dishevelled-1: DEP domain is responsible for membrane translocation of dishevelled-1.
Pan WJ; Pang SZ; Huang T; Guo HY; Wu D; Li L
Cell Res; 2004 Aug; 14(4):324-30. PubMed ID: 15353129
[TBL] [Abstract][Full Text] [Related]
15. Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1.
Harnoš J; Cañizal MCA; Jurásek M; Kumar J; Holler C; Schambony A; Hanáková K; Bernatík O; Zdráhal Z; Gömöryová K; Gybeľ T; Radaszkiewicz TW; Kravec M; Trantírek L; Ryneš J; Dave Z; Fernández-Llamazares AI; Vácha R; Tripsianes K; Hoffmann C; Bryja V
Nat Commun; 2019 Apr; 10(1):1804. PubMed ID: 31000703
[TBL] [Abstract][Full Text] [Related]
16. Single-molecule dynamics of Dishevelled at the plasma membrane and Wnt pathway activation.
Ma W; Chen M; Kang H; Steinhart Z; Angers S; He X; Kirschner MW
Proc Natl Acad Sci U S A; 2020 Jul; 117(28):16690-16701. PubMed ID: 32601235
[TBL] [Abstract][Full Text] [Related]
17. Conformational change of Dishevelled plays a key regulatory role in the Wnt signaling pathways.
Lee HJ; Shi DL; Zheng JJ
Elife; 2015 Aug; 4():e08142. PubMed ID: 26297804
[TBL] [Abstract][Full Text] [Related]
18. Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteins.
Punchihewa C; Ferreira AM; Cassell R; Rodrigues P; Fujii N
Protein Sci; 2009 May; 18(5):994-1002. PubMed ID: 19388021
[TBL] [Abstract][Full Text] [Related]
19. PDZ domain from Dishevelled -- a specificity study.
Śmietana K; Mateja A; Krężel A; Otlewski J
Acta Biochim Pol; 2011; 58(2):243-9. PubMed ID: 21666888
[TBL] [Abstract][Full Text] [Related]
20. Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling.
Kamdem N; Roske Y; Kovalskyy D; Platonov MO; Balinskyi O; Kreuchwig A; Saupe J; Fang L; Diehl A; Schmieder P; Krause G; Rademann J; Heinemann U; Birchmeier W; Oschkinat H
Magn Reson (Gott); 2021; 2(1):355-374. PubMed ID: 37904770
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
