BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

244 related articles for article (PubMed ID: 27114609)

  • 1. Continuous inhibitory signaling by both SHP-1 and SHIP-1 pathways is required to maintain unresponsiveness of anergic B cells.
    Getahun A; Beavers NA; Larson SR; Shlomchik MJ; Cambier JC
    J Exp Med; 2016 May; 213(5):751-69. PubMed ID: 27114609
    [TBL] [Abstract][Full Text] [Related]  

  • 2. B cell expression of the SH2-containing inositol 5-phosphatase (SHIP-1) is required to establish anergy to high affinity, proteinacious autoantigens.
    Akerlund J; Getahun A; Cambier JC
    J Autoimmun; 2015 Aug; 62():45-54. PubMed ID: 26152931
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy.
    O'Neill SK; Getahun A; Gauld SB; Merrell KT; Tamir I; Smith MJ; Dal Porto JM; Li QZ; Cambier JC
    Immunity; 2011 Nov; 35(5):746-56. PubMed ID: 22078222
    [TBL] [Abstract][Full Text] [Related]  

  • 4. T-helper signals restore B-cell receptor signaling in autoreactive anergic B cells by upregulating CD45 phosphatase activity.
    Szodoray P; Stanford SM; Molberg Ø; Munthe LA; Bottini N; Nakken B
    J Allergy Clin Immunol; 2016 Sep; 138(3):839-851.e8. PubMed ID: 27056269
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection.
    Cornall RJ; Cyster JG; Hibbs ML; Dunn AR; Otipoby KL; Clark EA; Goodnow CC
    Immunity; 1998 Apr; 8(4):497-508. PubMed ID: 9586639
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Signaling mutations and autoimmunity.
    Yu CC; Mamchak AA; DeFranco AL
    Curr Dir Autoimmun; 2003; 6():61-88. PubMed ID: 12408047
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Putting on the Brakes: Regulatory Kinases and Phosphatases Maintaining B Cell Anergy.
    Franks SE; Cambier JC
    Front Immunol; 2018; 9():665. PubMed ID: 29681901
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Precision B Cell-Targeted Therapeutic Approach to Autoimmunity Caused by Phosphatidylinositol 3-Kinase Pathway Dysregulation.
    Franks SE; Getahun A; Cambier JC
    J Immunol; 2019 Jun; 202(12):3381-3393. PubMed ID: 31076529
    [TBL] [Abstract][Full Text] [Related]  

  • 9. B cell receptor signaling in human systemic lupus erythematosus.
    Pugh-Bernard AE; Cambier JC
    Curr Opin Rheumatol; 2006 Sep; 18(5):451-5. PubMed ID: 16896281
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Intravenous immunoglobulin induces a functional silencing program similar to anergy in human B cells.
    Séïté JF; Goutsmedt C; Youinou P; Pers JO; Hillion S
    J Allergy Clin Immunol; 2014 Jan; 133(1):181-8.e1-9. PubMed ID: 24139609
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SHIP-1 Deficiency in AID
    Chen Y; Hu F; Dong X; Zhao M; Wang J; Sun X; Kim TJ; Li Z; Liu W
    J Immunol; 2017 Nov; 199(9):3063-3073. PubMed ID: 28972092
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling.
    Gauld SB; Benschop RJ; Merrell KT; Cambier JC
    Nat Immunol; 2005 Nov; 6(11):1160-7. PubMed ID: 16200069
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cutting Edge: Deletion of Ezrin in B Cells of Lyn-Deficient Mice Downregulates Lupus Pathology.
    Pore D; Huang E; Dejanovic D; Parameswaran N; Cheung MB; Gupta N
    J Immunol; 2018 Sep; 201(5):1353-1358. PubMed ID: 30021765
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic interdependence of Lyn and negative regulators of B cell receptor signaling in autoimmune disease development.
    Tsantikos E; Maxwell MJ; Kountouri N; Harder KW; Tarlinton DM; Hibbs ML
    J Immunol; 2012 Aug; 189(4):1726-36. PubMed ID: 22798664
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Dok-3/Grb2 adaptor module promotes inducible association of the lipid phosphatase SHIP with the BCR in a coreceptor-independent manner.
    Manno B; Oellerich T; Schnyder T; Corso J; Lösing M; Neumann K; Urlaub H; Batista FD; Engelke M; Wienands J
    Eur J Immunol; 2016 Nov; 46(11):2520-2530. PubMed ID: 27550373
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FcγRIIB-Independent Mechanisms Controlling Membrane Localization of the Inhibitory Phosphatase SHIP in Human B Cells.
    Pauls SD; Ray A; Hou S; Vaughan AT; Cragg MS; Marshall AJ
    J Immunol; 2016 Sep; 197(5):1587-96. PubMed ID: 27456487
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting SHP-1, 2 and SHIP Pathways: A Novel Strategy for Cancer Treatment?
    Dempke WCM; Uciechowski P; Fenchel K; Chevassut T
    Oncology; 2018; 95(5):257-269. PubMed ID: 29925063
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Src-family kinase Lyn plays a critical role in establishing and maintaining B cell anergy by suppressing PI3K-dependent signaling.
    Fiske BE; Wemlinger SM; Crute BW; Getahun A
    bioRxiv; 2024 May; ():. PubMed ID: 38826354
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Suppression of phosphatidylinositol 3,4,5-trisphosphate production is a key determinant of B cell anergy.
    Browne CD; Del Nagro CJ; Cato MH; Dengler HS; Rickert RC
    Immunity; 2009 Nov; 31(5):749-60. PubMed ID: 19896393
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The phosphatidylinositol polyphosphate 5-phosphatase SHIP and the protein tyrosine phosphatase SHP-2 form a complex in hematopoietic cells which can be regulated by BCR/ABL and growth factors.
    Sattler M; Salgia R; Shrikhande G; Verma S; Choi JL; Rohrschneider LR; Griffin JD
    Oncogene; 1997 Nov; 15(19):2379-84. PubMed ID: 9393882
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.