These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

83 related articles for article (PubMed ID: 27115861)

  • 1. Aminoacetylation Reaction Catalyzed by Leucyl-tRNA Synthetase Operates via a Self-Assisted Mechanism Using a Conserved Residue and the Aminoacyl Substrate.
    Aleksandrov A; Palencia A; Cusack S; Field M
    J Phys Chem B; 2016 May; 120(19):4388-98. PubMed ID: 27115861
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular modeling study of the editing active site of Escherichia coli leucyl-tRNA synthetase: two amino acid binding sites in the editing domain.
    Lee KW; Briggs JM
    Proteins; 2004 Mar; 54(4):693-704. PubMed ID: 14997565
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Editing mechanism of aminoacyl-tRNA synthetases operates by a hybrid ribozyme/protein catalyst.
    Hagiwara Y; Field MJ; Nureki O; Tateno M
    J Am Chem Soc; 2010 Mar; 132(8):2751-8. PubMed ID: 20136139
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular modeling and molecular dynamics simulation study of archaeal leucyl-tRNA synthetase in complex with different mischarged tRNA in editing conformation.
    Rayevsky AV; Sharifi M; Tukalo MA
    J Mol Graph Model; 2017 Sep; 76():289-295. PubMed ID: 28743072
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination.
    Liu Y; Liao J; Zhu B; Wang ED; Ding J
    Biochem J; 2006 Mar; 394(Pt 2):399-407. PubMed ID: 16277600
    [TBL] [Abstract][Full Text] [Related]  

  • 6. LeuRS synthetase: a first-principles investigation of the water-mediated editing reaction.
    Boero M
    J Phys Chem B; 2011 Oct; 115(42):12276-86. PubMed ID: 21923161
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of the nucleophilic factors and the productive complex for the editing reaction by leucyl-tRNA synthetase.
    Hagiwara Y; Nureki O; Tateno M
    FEBS Lett; 2009 Jun; 583(12):1901-8. PubMed ID: 19463822
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural modelling of the complex of leucyl-tRNA synthetase and mis-aminoacylated tRNALeu.
    Hagiwara Y; Nureki O; Tateno M
    FEBS Lett; 2009 Feb; 583(4):825-30. PubMed ID: 19640470
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation of substrate specificity within the amino acid editing site of leucyl-tRNA synthetase.
    Zhai Y; Nawaz MH; Lee KW; Kirkbride E; Briggs JM; Martinis SA
    Biochemistry; 2007 Mar; 46(11):3331-7. PubMed ID: 17311409
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Binding free energies and free energy components from molecular dynamics and Poisson-Boltzmann calculations. Application to amino acid recognition by aspartyl-tRNA synthetase.
    Archontis G; Simonson T; Karplus M
    J Mol Biol; 2001 Feb; 306(2):307-27. PubMed ID: 11237602
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Two conserved threonines collaborate in the Escherichia coli leucyl-tRNA synthetase amino acid editing mechanism.
    Zhai Y; Martinis SA
    Biochemistry; 2005 Nov; 44(47):15437-43. PubMed ID: 16300391
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interdomain communication modulates the tRNA-dependent pre-transfer editing of leucyl-tRNA synthetase.
    Tan M; Zhu B; Liu RJ; Chen X; Zhou XL; Wang ED
    Biochem J; 2013 Jan; 449(1):123-31. PubMed ID: 23035846
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural dynamics of the aminoacylation and proofreading functional cycle of bacterial leucyl-tRNA synthetase.
    Palencia A; Crépin T; Vu MT; Lincecum TL; Martinis SA; Cusack S
    Nat Struct Mol Biol; 2012 Jun; 19(7):677-84. PubMed ID: 22683997
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The 2 A crystal structure of leucyl-tRNA synthetase and its complex with a leucyl-adenylate analogue.
    Cusack S; Yaremchuk A; Tukalo M
    EMBO J; 2000 May; 19(10):2351-61. PubMed ID: 10811626
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Acetylation of lysine ϵ-amino groups regulates aminoacyl-tRNA synthetase activity in
    Ye Q; Ji QQ; Yan W; Yang F; Wang ED
    J Biol Chem; 2017 Jun; 292(25):10709-10722. PubMed ID: 28455447
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The C-terminal appended domain of human cytosolic leucyl-tRNA synthetase is indispensable in its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex.
    Ling C; Yao YN; Zheng YG; Wei H; Wang L; Wu XF; Wang ED
    J Biol Chem; 2005 Oct; 280(41):34755-63. PubMed ID: 16055448
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Multiple Proton Transfer Mechanism for the Charging Step of the Aminoacylation Reaction at the Active Site of Aspartyl tRNA Synthetase.
    Dutta S; Chandra A
    J Chem Inf Model; 2023 Mar; 63(6):1819-1832. PubMed ID: 36893463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evolutionary basis for the coupled-domain motions in Thermus thermophilus leucyl-tRNA synthetase.
    Weimer KM; Shane BL; Brunetto M; Bhattacharyya S; Hati S
    J Biol Chem; 2009 Apr; 284(15):10088-99. PubMed ID: 19188368
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The beta subunit of Aquifex aeolicus leucyl-tRNA synthetase is responsible for cognate tRNA recognition.
    Gouda M; Yokogawa T; Nishikawa K
    Biochem Biophys Res Commun; 2002 Oct; 297(4):950-5. PubMed ID: 12359246
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Substrate-assisted catalysis in the aminoacyl transfer mechanism of histidyl-tRNA synthetase: a density functional theory study.
    Liu H; Gauld JW
    J Phys Chem B; 2008 Dec; 112(51):16874-82. PubMed ID: 19367912
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.