BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 27125377)

  • 1. Engagement of CD22 on B cells with the monoclonal antibody epratuzumab stimulates the phosphorylation of upstream inhibitory signals of the B cell receptor.
    Lumb S; Fleischer SJ; Wiedemann A; Daridon C; Maloney A; Shock A; Dörner T
    J Cell Commun Signal; 2016 Jun; 10(2):143-51. PubMed ID: 27125377
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel binding site for Src homology 2-containing protein-tyrosine phosphatase-1 in CD22 activated by B lymphocyte stimulation with antigen.
    Zhu C; Sato M; Yanagisawa T; Fujimoto M; Adachi T; Tsubata T
    J Biol Chem; 2008 Jan; 283(3):1653-1659. PubMed ID: 18024433
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CD22 ligation inhibits downstream B cell receptor signaling and Ca(2+) flux upon activation.
    Sieger N; Fleischer SJ; Mei HE; Reiter K; Shock A; Burmester GR; Daridon C; Dörner T
    Arthritis Rheum; 2013 Mar; 65(3):770-9. PubMed ID: 23233360
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Extensive crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in human lymphoma cells.
    Chang CH; Wang Y; Gupta P; Goldenberg DM
    MAbs; 2015; 7(1):199-211. PubMed ID: 25484043
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Besides an ITIM/SHP-1-dependent pathway, CD22 collaborates with Grb2 and plasma membrane calcium-ATPase in an ITIM/SHP-1-independent pathway of attenuation of Ca2+i signal in B cells.
    Chen J; Wang H; Xu WP; Wei SS; Li HJ; Mei YQ; Li YG; Wang YP
    Oncotarget; 2016 Aug; 7(35):56129-56146. PubMed ID: 27276708
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The mechanistic impact of CD22 engagement with epratuzumab on B cell function: Implications for the treatment of systemic lupus erythematosus.
    Dörner T; Shock A; Goldenberg DM; Lipsky PE
    Autoimmun Rev; 2015 Dec; 14(12):1079-86. PubMed ID: 26212727
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Epratuzumab, a humanized monoclonal antibody targeting CD22: characterization of in vitro properties.
    Carnahan J; Wang P; Kendall R; Chen C; Hu S; Boone T; Juan T; Talvenheimo J; Montestruque S; Sun J; Elliott G; Thomas J; Ferbas J; Kern B; Briddell R; Leonard JP; Cesano A
    Clin Cancer Res; 2003 Sep; 9(10 Pt 2):3982S-90S. PubMed ID: 14506197
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CD22 is a negative regulator of B-cell receptor signalling.
    Nitschke L; Carsetti R; Ocker B; Köhler G; Lamers MC
    Curr Biol; 1997 Feb; 7(2):133-43. PubMed ID: 9016707
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting CD22 with the monoclonal antibody epratuzumab modulates human B-cell maturation and cytokine production in response to Toll-like receptor 7 (TLR7) and B-cell receptor (BCR) signaling.
    Giltiay NV; Shu GL; Shock A; Clark EA
    Arthritis Res Ther; 2017 May; 19(1):91. PubMed ID: 28506291
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Epratuzumab inhibits the production of the proinflammatory cytokines IL-6 and TNF-α, but not the regulatory cytokine IL-10, by B cells from healthy donors and SLE patients.
    Fleischer V; Sieber J; Fleischer SJ; Shock A; Heine G; Daridon C; Dörner T
    Arthritis Res Ther; 2015 Jul; 17(1):185. PubMed ID: 26183319
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Epratuzumab modulates B-cell signaling without affecting B-cell numbers or B-cell functions in a mouse model with humanized CD22.
    Özgör L; Brandl C; Shock A; Nitschke L
    Eur J Immunol; 2016 Sep; 46(9):2260-72. PubMed ID: 27352780
    [TBL] [Abstract][Full Text] [Related]  

  • 12. B cell antigen receptor and CD40 differentially regulate CD22 tyrosine phosphorylation.
    Fujimoto M; Kuwano Y; Watanabe R; Asashima N; Nakashima H; Yoshitake S; Okochi H; Tamaki K; Poe JC; Tedder TF; Sato S
    J Immunol; 2006 Jan; 176(2):873-9. PubMed ID: 16393971
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of CD22 and other inhibitory co-receptors in B-cell activation.
    Nitschke L
    Curr Opin Immunol; 2005 Jun; 17(3):290-7. PubMed ID: 15886119
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Epratuzumab, a CD22-targeting recombinant humanized antibody with a different mode of action from rituximab.
    Carnahan J; Stein R; Qu Z; Hess K; Cesano A; Hansen HJ; Goldenberg DM
    Mol Immunol; 2007 Feb; 44(6):1331-41. PubMed ID: 16814387
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CD22 and Siglec-G: B-cell inhibitory receptors with distinct functions.
    Nitschke L
    Immunol Rev; 2009 Jul; 230(1):128-43. PubMed ID: 19594633
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fc receptor-like 5 inhibits B cell activation via SHP-1 tyrosine phosphatase recruitment.
    Haga CL; Ehrhardt GR; Boohaker RJ; Davis RS; Cooper MD
    Proc Natl Acad Sci U S A; 2007 Jun; 104(23):9770-5. PubMed ID: 17522256
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enhanced Tyrosine Phosphatase Activity Underlies Dysregulated B Cell Receptor Signaling and Promotes Survival of Human Lupus B Cells.
    Fleischer SJ; Daridon C; Fleischer V; Lipsky PE; Dörner T
    Arthritis Rheumatol; 2016 May; 68(5):1210-21. PubMed ID: 26713408
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes.
    Chan VW; Lowell CA; DeFranco AL
    Curr Biol; 1998 May; 8(10):545-53. PubMed ID: 9601638
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of a new humanized anti-CD20 monoclonal antibody, IMMU-106, and Its use in combination with the humanized anti-CD22 antibody, epratuzumab, for the therapy of non-Hodgkin's lymphoma.
    Stein R; Qu Z; Chen S; Rosario A; Shi V; Hayes M; Horak ID; Hansen HJ; Goldenberg DM
    Clin Cancer Res; 2004 Apr; 10(8):2868-78. PubMed ID: 15102696
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential roles of N- and C-terminal immunoreceptor tyrosine-based inhibition motifs during inhibition of cell activation by killer cell inhibitory receptors.
    Bruhns P; Marchetti P; Fridman WH; Vivier E; Daëron M
    J Immunol; 1999 Mar; 162(6):3168-75. PubMed ID: 10092767
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.