These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 27130838)

  • 1. The KCC2 Cotransporter and Human Epilepsy: Getting Excited About Inhibition.
    Kahle KT; Khanna AR; Duan J; Staley KJ; Delpire E; Poduri A
    Neuroscientist; 2016 Dec; 22(6):555-562. PubMed ID: 27130838
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutations in SLC12A5 in epilepsy of infancy with migrating focal seizures.
    Stödberg T; McTague A; Ruiz AJ; Hirata H; Zhen J; Long P; Farabella I; Meyer E; Kawahara A; Vassallo G; Stivaros SM; Bjursell MK; Stranneheim H; Tigerschiöld S; Persson B; Bangash I; Das K; Hughes D; Lesko N; Lundeberg J; Scott RC; Poduri A; Scheffer IE; Smith H; Gissen P; Schorge S; Reith ME; Topf M; Kullmann DM; Harvey RJ; Wedell A; Kurian MA
    Nat Commun; 2015 Sep; 6():8038. PubMed ID: 26333769
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Impaired neuronal KCC2 function by biallelic SLC12A5 mutations in migrating focal seizures and severe developmental delay.
    Saitsu H; Watanabe M; Akita T; Ohba C; Sugai K; Ong WP; Shiraishi H; Yuasa S; Matsumoto H; Beng KT; Saitoh S; Miyatake S; Nakashima M; Miyake N; Kato M; Fukuda A; Matsumoto N
    Sci Rep; 2016 Jul; 6():30072. PubMed ID: 27436767
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pathogenic potential of human SLC12A5 variants causing KCC2 dysfunction.
    Fukuda A; Watanabe M
    Brain Res; 2019 May; 1710():1-7. PubMed ID: 30576625
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Seizing Control of KCC2: A New Therapeutic Target for Epilepsy.
    Moore YE; Kelley MR; Brandon NJ; Deeb TZ; Moss SJ
    Trends Neurosci; 2017 Sep; 40(9):555-571. PubMed ID: 28803659
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genetically encoded impairment of neuronal KCC2 cotransporter function in human idiopathic generalized epilepsy.
    Kahle KT; Merner ND; Friedel P; Silayeva L; Liang B; Khanna A; Shang Y; Lachance-Touchette P; Bourassa C; Levert A; Dion PA; Walcott B; Spiegelman D; Dionne-Laporte A; Hodgkinson A; Awadalla P; Nikbakht H; Majewski J; Cossette P; Deeb TZ; Moss SJ; Medina I; Rouleau GA
    EMBO Rep; 2014 Jul; 15(7):766-74. PubMed ID: 24928908
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A de novo missense mutation in SLC12A5 found in a compound heterozygote patient with epilepsy of infancy with migrating focal seizures.
    Saito T; Ishii A; Sugai K; Sasaki M; Hirose S
    Clin Genet; 2017 Dec; 92(6):654-658. PubMed ID: 28477354
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel pathogenic
    Järvelä V; Hamze M; Komulainen-Ebrahim J; Rahikkala E; Piispala J; Kallio M; Kangas SM; Nickl T; Huttula M; Hinttala R; Uusimaa J; Medina I; Immonen EV
    Front Mol Neurosci; 2024; 17():1372662. PubMed ID: 38660387
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Potentiating KCC2 activity is sufficient to limit the onset and severity of seizures.
    Moore YE; Deeb TZ; Chadchankar H; Brandon NJ; Moss SJ
    Proc Natl Acad Sci U S A; 2018 Oct; 115(40):10166-10171. PubMed ID: 30224498
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A noninvasive optical approach for assessing chloride extrusion activity of the K-Cl cotransporter KCC2 in neuronal cells.
    Ludwig A; Rivera C; Uvarov P
    BMC Neurosci; 2017 Jan; 18(1):23. PubMed ID: 28143398
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neuronal K
    McMoneagle E; Zhou J; Zhang S; Huang W; Josiah SS; Ding K; Wang Y; Zhang J
    Acta Pharmacol Sin; 2024 Jan; 45(1):1-22. PubMed ID: 37704745
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential expression patterns of chloride transporters, Na+-K+-2Cl--cotransporter and K+-Cl--cotransporter, in epilepsy-associated malformations of cortical development.
    Aronica E; Boer K; Redeker S; Spliet WG; van Rijen PC; Troost D; Gorter JA
    Neuroscience; 2007 Mar; 145(1):185-96. PubMed ID: 17207578
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Compromised GABAergic inhibition contributes to tumor-associated epilepsy.
    MacKenzie G; O'Toole KK; Moss SJ; Maguire J
    Epilepsy Res; 2016 Oct; 126():185-96. PubMed ID: 27513374
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A variant of KCC2 from patients with febrile seizures impairs neuronal Cl- extrusion and dendritic spine formation.
    Puskarjov M; Seja P; Heron SE; Williams TC; Ahmad F; Iona X; Oliver KL; Grinton BE; Vutskits L; Scheffer IE; Petrou S; Blaesse P; Dibbens LM; Berkovic SF; Kaila K
    EMBO Rep; 2014 Jun; 15(6):723-9. PubMed ID: 24668262
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reduced Efficacy of the KCC2 Cotransporter Promotes Epileptic Oscillations in a Subiculum Network Model.
    Buchin A; Chizhov A; Huberfeld G; Miles R; Gutkin BS
    J Neurosci; 2016 Nov; 36(46):11619-11633. PubMed ID: 27852771
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of KCC2 Mutations in Human Epilepsy Suggests Strategies for Therapeutic Transporter Modulation.
    Duy PQ; David WB; Kahle KT
    Front Cell Neurosci; 2019; 13():515. PubMed ID: 31803025
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CIP1 is an activator of the K+-Cl- cotransporter KCC2.
    Wenz M; Hartmann AM; Friauf E; Nothwang HG
    Biochem Biophys Res Commun; 2009 Apr; 381(3):388-92. PubMed ID: 19232517
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Preclinical insights into therapeutic targeting of KCC2 for disorders of neuronal hyperexcitability.
    Duy PQ; He M; He Z; Kahle KT
    Expert Opin Ther Targets; 2020 Jul; 24(7):629-637. PubMed ID: 32336175
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Anomalous levels of Cl- transporters cause a decrease of GABAergic inhibition in human peritumoral epileptic cortex.
    Conti L; Palma E; Roseti C; Lauro C; Cipriani R; de Groot M; Aronica E; Limatola C
    Epilepsia; 2011 Sep; 52(9):1635-44. PubMed ID: 21635237
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human and murine phenotypes associated with defects in cation-chloride cotransport.
    Delpire E; Mount DB
    Annu Rev Physiol; 2002; 64():803-43. PubMed ID: 11826289
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.