171 related articles for article (PubMed ID: 27132867)
1. Structure-guided development of dual β2 adrenergic/dopamine D2 receptor agonists.
Weichert D; Stanek M; Hübner H; Gmeiner P
Bioorg Med Chem; 2016 Jun; 24(12):2641-53. PubMed ID: 27132867
[TBL] [Abstract][Full Text] [Related]
2. Discovery of indolylpiperazinylpyrimidines with dual-target profiles at adenosine A2A and dopamine D2 receptors for Parkinson's disease treatment.
Shao YM; Ma X; Paira P; Tan A; Herr DR; Lim KL; Ng CH; Venkatesan G; Klotz KN; Federico S; Spalluto G; Cheong SL; Chen YZ; Pastorin G
PLoS One; 2018; 13(1):e0188212. PubMed ID: 29304113
[TBL] [Abstract][Full Text] [Related]
3. Conformation guides molecular efficacy in docking screens of activated β-2 adrenergic G protein coupled receptor.
Weiss DR; Ahn S; Sassano MF; Kleist A; Zhu X; Strachan R; Roth BL; Lefkowitz RJ; Shoichet BK
ACS Chem Biol; 2013 May; 8(5):1018-26. PubMed ID: 23485065
[TBL] [Abstract][Full Text] [Related]
4. In vitro characterization of SLV308 (7-[4-methyl-1-piperazinyl]-2(3H)-benzoxazolone, monohydrochloride): a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist.
Glennon JC; Van Scharrenburg G; Ronken E; Hesselink MB; Reinders JH; Van Der Neut M; Long SK; Feenstra RW; McCreary AC
Synapse; 2006 Dec; 60(8):599-608. PubMed ID: 17001660
[TBL] [Abstract][Full Text] [Related]
5. CoMFA-based prediction of agonist affinities at recombinant D1 vs D2 dopamine receptors.
Wilcox RE; Tseng T; Brusniak MY; Ginsburg B; Pearlman RS; Teeter M; DuRand C; Starr S; Neve KA
J Med Chem; 1998 Oct; 41(22):4385-99. PubMed ID: 9784114
[TBL] [Abstract][Full Text] [Related]
6. Structure-Based Prediction of G-Protein-Coupled Receptor Ligand Function: A β-Adrenoceptor Case Study.
Kooistra AJ; Leurs R; de Esch IJ; de Graaf C
J Chem Inf Model; 2015 May; 55(5):1045-61. PubMed ID: 25848966
[TBL] [Abstract][Full Text] [Related]
7. Pharmacological profile of 2-bromoterguride at human dopamine D2, porcine serotonin 5-hydroxytryptamine 2A, and α2C-adrenergic receptors, and its antipsychotic-like effects in rats.
Jantschak F; Brosda J; Franke RT; Fink H; Möller D; Hübner H; Gmeiner P; Pertz HH
J Pharmacol Exp Ther; 2013 Oct; 347(1):57-68. PubMed ID: 23863695
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and pharmacological evaluation of dual acting ligands targeting the adenosine A2A and dopamine D2 receptors for the potential treatment of Parkinson's disease.
Jörg M; May LT; Mak FS; Lee KC; Miller ND; Scammells PJ; Capuano B
J Med Chem; 2015 Jan; 58(2):718-38. PubMed ID: 25490054
[TBL] [Abstract][Full Text] [Related]
9. In Vitro and In Vivo Identification of Novel Positive Allosteric Modulators of the Human Dopamine D2 and D3 Receptor.
Wood M; Ates A; Andre VM; Michel A; Barnaby R; Gillard M
Mol Pharmacol; 2016 Feb; 89(2):303-12. PubMed ID: 26655303
[TBL] [Abstract][Full Text] [Related]
10. Discovery of a true bivalent dopamine D
Qian M; Ricarte A; Wouters E; Dalton JAR; Risseeuw MDP; Giraldo J; Van Calenbergh S
Eur J Med Chem; 2021 Feb; 212():113151. PubMed ID: 33450620
[TBL] [Abstract][Full Text] [Related]
11. β-Arrestin biased dopamine D2 receptor partial agonists: Synthesis and pharmacological evaluation.
Männel B; Hübner H; Möller D; Gmeiner P
Bioorg Med Chem; 2017 Oct; 25(20):5613-5628. PubMed ID: 28870802
[TBL] [Abstract][Full Text] [Related]
12. Aplindore (DAB-452), a high affinity selective dopamine D2 receptor partial agonist.
Heinrich JN; Brennan J; Lai MH; Sullivan K; Hornby G; Popiolek M; Jiang LX; Pausch MH; Stack G; Marquis KL; Andree TH
Eur J Pharmacol; 2006 Dec; 552(1-3):36-45. PubMed ID: 17056032
[TBL] [Abstract][Full Text] [Related]
13. Receptor-dependent regulation of dendrite formation of noradrenaline and dopamine in non-GABAergic cerebral cortical neurons.
Li F; Ohtani A; Senzaki K; Shiga T
Dev Neurobiol; 2013 May; 73(5):370-83. PubMed ID: 23135899
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and evaluation in rats of the dopamine D2/3 receptor agonist 18F-AMC20 as a potential radioligand for PET.
Shalgunov V; van Wieringen JP; Janssen HM; Fransen PM; Dierckx RA; Michel MC; Booij J; Elsinga PH
J Nucl Med; 2015 Jan; 56(1):133-9. PubMed ID: 25476538
[TBL] [Abstract][Full Text] [Related]
15. Hydroxy-Substituted Heteroarylpiperazines: Novel Scaffolds for β-Arrestin-Biased D
Männel B; Dengler D; Shonberg J; Hübner H; Möller D; Gmeiner P
J Med Chem; 2017 Jun; 60(11):4693-4713. PubMed ID: 28489379
[TBL] [Abstract][Full Text] [Related]
16. Dual D2-receptor and beta2-adrenoceptor agonists for the treatment of airway diseases. 1. Discovery and biological evaluation of some 7-(2-aminoethyl)-4-hydroxybenzothiazol-2(3H)-one analogues.
Bonnert RV; Brown RC; Chapman D; Cheshire DR; Dixon J; Ince F; Kinchin EC; Lyons AJ; Davis AM; Hallam C; Harper ST; Unitt JF; Dougall IG; Jackson DM; McKechnie K; Young A; Simpson WT
J Med Chem; 1998 Dec; 41(25):4915-7. PubMed ID: 9836607
[No Abstract] [Full Text] [Related]
17. Modulations of the amide function of the preferential dopamine D3 agonist (R,R)-S32504: improvements of affinity and selectivity for D3 versus D2 receptors.
Peglion JL; Poitevin C; Mannoury La Cour C; Dupuis D; Millan MJ
Bioorg Med Chem Lett; 2009 Apr; 19(8):2133-8. PubMed ID: 19324548
[TBL] [Abstract][Full Text] [Related]
18. Molecular dynamics simulations of the effect of the G-protein and diffusible ligands on the β2-adrenergic receptor.
Goetz A; Lanig H; Gmeiner P; Clark T
J Mol Biol; 2011 Dec; 414(4):611-23. PubMed ID: 22037586
[TBL] [Abstract][Full Text] [Related]
19. Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody.
Ring AM; Manglik A; Kruse AC; Enos MD; Weis WI; Garcia KC; Kobilka BK
Nature; 2013 Oct; 502(7472):575-579. PubMed ID: 24056936
[TBL] [Abstract][Full Text] [Related]
20. Long Receptor Residence Time of C26 Contributes to Super Agonist Activity at the Human β2 Adrenoceptor.
Rosethorne EM; Bradley ME; Gherbi K; Sykes DA; Sattikar A; Wright JD; Renard E; Trifilieff A; Fairhurst RA; Charlton SJ
Mol Pharmacol; 2016 Apr; 89(4):467-75. PubMed ID: 26772612
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
