52 related articles for article (PubMed ID: 27135648)
1. Vacuolin-1 inhibits autophagy by impairing lysosomal maturation via PIKfyve inhibition.
Sano O; Kazetani K; Funata M; Fukuda Y; Matsui J; Iwata H
FEBS Lett; 2016 Jun; 590(11):1576-85. PubMed ID: 27135648
[TBL] [Abstract][Full Text] [Related]
2. PIKfyve inhibition increases exosome release and induces secretory autophagy.
Hessvik NP; Øverbye A; Brech A; Torgersen ML; Jakobsen IS; Sandvig K; Llorente A
Cell Mol Life Sci; 2016 Dec; 73(24):4717-4737. PubMed ID: 27438886
[TBL] [Abstract][Full Text] [Related]
3. Vacuolin-1 inhibits endosomal trafficking and metastasis via CapZβ.
Ye Z; Wang D; Lu Y; He Y; Yu J; Wei W; Chen C; Wang R; Zhang L; Zhang L; Le MTN; Cho WC; Yang M; Zhang H; Yue J
Oncogene; 2021 Mar; 40(10):1775-1791. PubMed ID: 33564074
[TBL] [Abstract][Full Text] [Related]
4. Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control.
Wible DJ; Parikh Z; Cho EJ; Chen MD; Mukhopadhyay S; Dalby KN; Varadarajan S; Bratton SB
bioRxiv; 2023 Mar; ():. PubMed ID: 36993747
[TBL] [Abstract][Full Text] [Related]
5. Discovery of a First-in-Class Degrader for the Lipid Kinase PIKfyve.
Li C; Qiao Y; Jiang X; Liu L; Zheng Y; Qiu Y; Cheng C; Zhou F; Zhou Y; Huang W; Ren X; Wang Y; Wang Z; Chinnaiyan AM; Ding K
J Med Chem; 2023 Sep; 66(17):12432-12445. PubMed ID: 37605297
[TBL] [Abstract][Full Text] [Related]
6. Chemical modulators of autophagy as biological probes and potential therapeutics.
Fleming A; Noda T; Yoshimori T; Rubinsztein DC
Nat Chem Biol; 2011 Jan; 7(1):9-17. PubMed ID: 21164513
[TBL] [Abstract][Full Text] [Related]
7. Discovery of Potent and Selective Phosphatidylinositol 3-Phosphate 5-Kinase (PIKfyve) Inhibitors as Methuosis Inducers.
Chen Y; Liu S; Wei Y; Wei H; Yuan X; Xiong B; Tang M; Yang T; Yang Z; Ye H; Yang J; Chen L
J Med Chem; 2024 Jan; 67(1):165-179. PubMed ID: 38117948
[TBL] [Abstract][Full Text] [Related]
8. Uridine-Modified Ruthenium(II) Complex as Lysosomal LIMP-2 Targeting Photodynamic Therapy Photosensitizer for the Treatment of Triple-Negative Breast Cancer.
Wu Q; Yuan C; Wang J; Li G; Zhu C; Li L; Wang Z; Lv Q; Mei W
JACS Au; 2024 Mar; 4(3):1081-1096. PubMed ID: 38559730
[TBL] [Abstract][Full Text] [Related]
9. PIKFYVE inhibitors trigger interleukin-24-dependent cell death of autophagy-dependent melanoma.
Roy A; Chakraborty AR; DePamphilis ML
Mol Oncol; 2024 Apr; 18(4):988-1011. PubMed ID: 38414326
[TBL] [Abstract][Full Text] [Related]
10. Amphetamine Induces Sex-Dependent Loss of the Striatal Dopamine Transporter in Sensitized Mice.
Bagalkot T; Sorkin A
eNeuro; 2024 Jan; 11(1):. PubMed ID: 38164591
[TBL] [Abstract][Full Text] [Related]
11. HBZ upregulates myoferlin expression to facilitate HTLV-1 infection.
Polakowski N; Sarker MAK; Hoang K; Boateng G; Rushing AW; Kendle W; Pique C; Green PL; Panfil AR; Lemasson I
PLoS Pathog; 2023 Feb; 19(2):e1011202. PubMed ID: 36827461
[TBL] [Abstract][Full Text] [Related]
12. Two-pore channels: going with the flows.
Morgan AJ; Martucci LL; Davis LC; Galione A
Biochem Soc Trans; 2022 Aug; 50(4):1143-1155. PubMed ID: 35959977
[TBL] [Abstract][Full Text] [Related]
13. Autophagy in health and disease: From molecular mechanisms to therapeutic target.
Lu G; Wang Y; Shi Y; Zhang Z; Huang C; He W; Wang C; Shen HM
MedComm (2020); 2022 Sep; 3(3):e150. PubMed ID: 35845350
[TBL] [Abstract][Full Text] [Related]
14. From Pinocytosis to Methuosis-Fluid Consumption as a Risk Factor for Cell Death.
Ritter M; Bresgen N; Kerschbaum HH
Front Cell Dev Biol; 2021; 9():651982. PubMed ID: 34249909
[TBL] [Abstract][Full Text] [Related]
15. Kinase Inhibitors as Underexplored Antiviral Agents.
García-Cárceles J; Caballero E; Gil C; Martínez A
J Med Chem; 2022 Jan; 65(2):935-954. PubMed ID: 33970631
[TBL] [Abstract][Full Text] [Related]
16. Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells.
O'Connell CE; Vassilev A
Cancer Res; 2021 Jun; 81(11):2903-2917. PubMed ID: 33685990
[TBL] [Abstract][Full Text] [Related]
17. The D614G Mutation Enhances the Lysosomal Trafficking of SARS-CoV-2 Spike.
Guo C; Tsai SJ; Ai Y; Li M; Pekosz A; Cox A; Atai N; Gould SJ
bioRxiv; 2020 Dec; ():. PubMed ID: 33330866
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2.
Kang YL; Chou YY; Rothlauf PW; Liu Z; Soh TK; Cureton D; Case JB; Chen RE; Diamond MS; Whelan SPJ; Kirchhausen T
Proc Natl Acad Sci U S A; 2020 Aug; 117(34):20803-20813. PubMed ID: 32764148
[TBL] [Abstract][Full Text] [Related]
19. PIKfyve Deficiency in Myeloid Cells Impairs Lysosomal Homeostasis in Macrophages and Promotes Systemic Inflammation in Mice.
Min SH; Suzuki A; Weaver L; Guzman J; Chung Y; Jin H; Gonzalez F; Trasorras C; Zhao L; Spruce LA; Seeholzer SH; Behrens EM; Abrams CS
Mol Cell Biol; 2019 Nov; 39(21):. PubMed ID: 31427458
[TBL] [Abstract][Full Text] [Related]
20. A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis.
Sharma G; Guardia CM; Roy A; Vassilev A; Saric A; Griner LN; Marugan J; Ferrer M; Bonifacino JS; DePamphilis ML
Autophagy; 2019 Oct; 15(10):1694-1718. PubMed ID: 30806145
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]