BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

52 related articles for article (PubMed ID: 27135648)

  • 1. Vacuolin-1 inhibits autophagy by impairing lysosomal maturation via PIKfyve inhibition.
    Sano O; Kazetani K; Funata M; Fukuda Y; Matsui J; Iwata H
    FEBS Lett; 2016 Jun; 590(11):1576-85. PubMed ID: 27135648
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PIKfyve inhibition increases exosome release and induces secretory autophagy.
    Hessvik NP; Øverbye A; Brech A; Torgersen ML; Jakobsen IS; Sandvig K; Llorente A
    Cell Mol Life Sci; 2016 Dec; 73(24):4717-4737. PubMed ID: 27438886
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Vacuolin-1 inhibits endosomal trafficking and metastasis via CapZβ.
    Ye Z; Wang D; Lu Y; He Y; Yu J; Wei W; Chen C; Wang R; Zhang L; Zhang L; Le MTN; Cho WC; Yang M; Zhang H; Yue J
    Oncogene; 2021 Mar; 40(10):1775-1791. PubMed ID: 33564074
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control.
    Wible DJ; Parikh Z; Cho EJ; Chen MD; Mukhopadhyay S; Dalby KN; Varadarajan S; Bratton SB
    bioRxiv; 2023 Mar; ():. PubMed ID: 36993747
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of a First-in-Class Degrader for the Lipid Kinase PIKfyve.
    Li C; Qiao Y; Jiang X; Liu L; Zheng Y; Qiu Y; Cheng C; Zhou F; Zhou Y; Huang W; Ren X; Wang Y; Wang Z; Chinnaiyan AM; Ding K
    J Med Chem; 2023 Sep; 66(17):12432-12445. PubMed ID: 37605297
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chemical modulators of autophagy as biological probes and potential therapeutics.
    Fleming A; Noda T; Yoshimori T; Rubinsztein DC
    Nat Chem Biol; 2011 Jan; 7(1):9-17. PubMed ID: 21164513
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of Potent and Selective Phosphatidylinositol 3-Phosphate 5-Kinase (PIKfyve) Inhibitors as Methuosis Inducers.
    Chen Y; Liu S; Wei Y; Wei H; Yuan X; Xiong B; Tang M; Yang T; Yang Z; Ye H; Yang J; Chen L
    J Med Chem; 2024 Jan; 67(1):165-179. PubMed ID: 38117948
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Uridine-Modified Ruthenium(II) Complex as Lysosomal LIMP-2 Targeting Photodynamic Therapy Photosensitizer for the Treatment of Triple-Negative Breast Cancer.
    Wu Q; Yuan C; Wang J; Li G; Zhu C; Li L; Wang Z; Lv Q; Mei W
    JACS Au; 2024 Mar; 4(3):1081-1096. PubMed ID: 38559730
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PIKFYVE inhibitors trigger interleukin-24-dependent cell death of autophagy-dependent melanoma.
    Roy A; Chakraborty AR; DePamphilis ML
    Mol Oncol; 2024 Apr; 18(4):988-1011. PubMed ID: 38414326
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amphetamine Induces Sex-Dependent Loss of the Striatal Dopamine Transporter in Sensitized Mice.
    Bagalkot T; Sorkin A
    eNeuro; 2024 Jan; 11(1):. PubMed ID: 38164591
    [TBL] [Abstract][Full Text] [Related]  

  • 11. HBZ upregulates myoferlin expression to facilitate HTLV-1 infection.
    Polakowski N; Sarker MAK; Hoang K; Boateng G; Rushing AW; Kendle W; Pique C; Green PL; Panfil AR; Lemasson I
    PLoS Pathog; 2023 Feb; 19(2):e1011202. PubMed ID: 36827461
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Two-pore channels: going with the flows.
    Morgan AJ; Martucci LL; Davis LC; Galione A
    Biochem Soc Trans; 2022 Aug; 50(4):1143-1155. PubMed ID: 35959977
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Autophagy in health and disease: From molecular mechanisms to therapeutic target.
    Lu G; Wang Y; Shi Y; Zhang Z; Huang C; He W; Wang C; Shen HM
    MedComm (2020); 2022 Sep; 3(3):e150. PubMed ID: 35845350
    [TBL] [Abstract][Full Text] [Related]  

  • 14. From Pinocytosis to Methuosis-Fluid Consumption as a Risk Factor for Cell Death.
    Ritter M; Bresgen N; Kerschbaum HH
    Front Cell Dev Biol; 2021; 9():651982. PubMed ID: 34249909
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinase Inhibitors as Underexplored Antiviral Agents.
    García-Cárceles J; Caballero E; Gil C; Martínez A
    J Med Chem; 2022 Jan; 65(2):935-954. PubMed ID: 33970631
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells.
    O'Connell CE; Vassilev A
    Cancer Res; 2021 Jun; 81(11):2903-2917. PubMed ID: 33685990
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The D614G Mutation Enhances the Lysosomal Trafficking of SARS-CoV-2 Spike.
    Guo C; Tsai SJ; Ai Y; Li M; Pekosz A; Cox A; Atai N; Gould SJ
    bioRxiv; 2020 Dec; ():. PubMed ID: 33330866
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2.
    Kang YL; Chou YY; Rothlauf PW; Liu Z; Soh TK; Cureton D; Case JB; Chen RE; Diamond MS; Whelan SPJ; Kirchhausen T
    Proc Natl Acad Sci U S A; 2020 Aug; 117(34):20803-20813. PubMed ID: 32764148
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PIKfyve Deficiency in Myeloid Cells Impairs Lysosomal Homeostasis in Macrophages and Promotes Systemic Inflammation in Mice.
    Min SH; Suzuki A; Weaver L; Guzman J; Chung Y; Jin H; Gonzalez F; Trasorras C; Zhao L; Spruce LA; Seeholzer SH; Behrens EM; Abrams CS
    Mol Cell Biol; 2019 Nov; 39(21):. PubMed ID: 31427458
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis.
    Sharma G; Guardia CM; Roy A; Vassilev A; Saric A; Griner LN; Marugan J; Ferrer M; Bonifacino JS; DePamphilis ML
    Autophagy; 2019 Oct; 15(10):1694-1718. PubMed ID: 30806145
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 3.