These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 27137342)

  • 1. Prediction of a novel internal rearrangement of the insulin receptor.
    Sit KC; van Lonkhuyzen D; Walsh T; Croll T
    J Biomol Struct Dyn; 2017 Mar; 35(4):857-867. PubMed ID: 27137342
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A thermodynamic study of ligand binding to the first three domains of the human insulin receptor: relationship between the receptor alpha-chain C-terminal peptide and the site 1 insulin mimetic peptides.
    Menting JG; Ward CW; Margetts MB; Lawrence MC
    Biochemistry; 2009 Jun; 48(23):5492-500. PubMed ID: 19459609
    [TBL] [Abstract][Full Text] [Related]  

  • 3. All-atom structural models of insulin binding to the insulin receptor in the presence of a tandem hormone-binding element.
    Vashisth H; Abrams CF
    Proteins; 2013 Jun; 81(6):1017-30. PubMed ID: 23348915
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Solution structure of ectodomains of the insulin receptor family: the ectodomain of the type 1 insulin-like growth factor receptor displays asymmetry of ligand binding accompanied by limited conformational change.
    Whitten AE; Smith BJ; Menting JG; Margetts MB; McKern NM; Lovrecz GO; Adams TE; Richards K; Bentley JD; Trewhella J; Ward CW; Lawrence MC
    J Mol Biol; 2009 Dec; 394(5):878-92. PubMed ID: 19835884
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rapid Non-Enzymatic Glycation of the Insulin Receptor under Hyperglycemic Conditions Inhibits Insulin Binding In Vitro: Implications for Insulin Resistance.
    Rhinesmith T; Turkette T; Root-Bernstein R
    Int J Mol Sci; 2017 Dec; 18(12):. PubMed ID: 29207492
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Structural and functional characteristics of insulin and mechanism of its effect].
    Prozorovskiĭ VN; Lokhov PG; Maslov DL; Ipatova OM
    Biomed Khim; 2003; 49(1):46-62. PubMed ID: 14569873
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Diabetes mellitus caused by mutations in human insulin: analysis of impaired receptor binding of insulins Wakayama, Los Angeles and Chicago using pharmacoinformatics.
    Islam MA; Bhayye S; Adeniyi AA; Soliman ME; Pillay TS
    J Biomol Struct Dyn; 2017 Mar; 35(4):724-737. PubMed ID: 26950281
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain.
    Croll TI; Smith BJ; Margetts MB; Whittaker J; Weiss MA; Ward CW; Lawrence MC
    Structure; 2016 Mar; 24(3):469-76. PubMed ID: 26853939
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional reconstitution of insulin receptor binding site from non-binding receptor fragments.
    Kristensen C; Andersen AS; Ostergaard S; Hansen PH; Brandt J
    J Biol Chem; 2002 May; 277(21):18340-5. PubMed ID: 11901156
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular mechanisms of differential intracellular signaling from the insulin receptor.
    Jensen M; De Meyts P
    Vitam Horm; 2009; 80():51-75. PubMed ID: 19251034
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The carboxyl-terminal domain of insulin-like growth factor-I receptor interacts with the insulin receptor and activates its protein tyrosine kinase.
    Li S; Termini J; Hayward A; Siddle K; Zick Y; Koval A; LeRoith D; Fujita-Yamaguchi Y
    FEBS Lett; 1998 Jan; 421(1):45-9. PubMed ID: 9462837
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Delineation of the IGF-II C domain elements involved in binding and activation of the IR-A, IR-B and IGF-IR.
    Henderson ST; Brierley GV; Surinya KH; Priebe IK; Catcheside DE; Wallace JC; Forbes BE; Cosgrove LJ
    Growth Horm IGF Res; 2015 Feb; 25(1):20-7. PubMed ID: 25458127
    [TBL] [Abstract][Full Text] [Related]  

  • 13. How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor.
    Huang K; Xu B; Hu SQ; Chu YC; Hua QX; Qu Y; Li B; Wang S; Wang RY; Nakagawa SH; Theede AM; Whittaker J; De Meyts P; Katsoyannis PG; Weiss MA
    J Mol Biol; 2004 Aug; 341(2):529-50. PubMed ID: 15276842
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The insulin and IGF1 receptor kinase domains are functional dimers in the activated state.
    Cabail MZ; Li S; Lemmon E; Bowen ME; Hubbard SR; Miller WT
    Nat Commun; 2015 Mar; 6():6406. PubMed ID: 25758790
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural insights into ligand-induced activation of the insulin receptor.
    Ward C; Lawrence M; Streltsov V; Garrett T; McKern N; Lou MZ; Lovrecz G; Adams T
    Acta Physiol (Oxf); 2008 Jan; 192(1):3-9. PubMed ID: 18171424
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Visualization of ligand-induced transmembrane signaling in the full-length human insulin receptor.
    Gutmann T; Kim KH; Grzybek M; Walz T; Coskun Ü
    J Cell Biol; 2018 May; 217(5):1643-1649. PubMed ID: 29453311
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of a second ligand binding site of the insulin receptor.
    Hao C; Whittaker L; Whittaker J
    Biochem Biophys Res Commun; 2006 Aug; 347(1):334-9. PubMed ID: 16814253
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of insulin receptor dimerization domains in ligand binding, cooperativity, and modulation by anti-receptor antibodies.
    Surinya KH; Molina L; Soos MA; Brandt J; Kristensen C; Siddle K
    J Biol Chem; 2002 May; 277(19):16718-25. PubMed ID: 11875066
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A structurally minimized yet fully active insulin based on cone-snail venom insulin principles.
    Xiong X; Menting JG; Disotuar MM; Smith NA; Delaine CA; Ghabash G; Agrawal R; Wang X; He X; Fisher SJ; MacRaild CA; Norton RS; Gajewiak J; Forbes BE; Smith BJ; Safavi-Hemami H; Olivera B; Lawrence MC; Chou DH
    Nat Struct Mol Biol; 2020 Jul; 27(7):615-624. PubMed ID: 32483339
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling.
    Nielsen J; Brandt J; Boesen T; Hummelshøj T; Slaaby R; Schluckebier G; Nissen P
    J Mol Biol; 2022 Mar; 434(5):167458. PubMed ID: 35074483
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.