BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 2713848)

  • 1. Dual effects of pyrazofurin and 3-deazauridine upon pyrimidine and purine biosynthesis in mouse L1210 leukemia.
    Sant ME; Lyons SD; Kemp AJ; McClure LK; Szabados E; Christopherson RI
    Cancer Res; 1989 May; 49(10):2645-50. PubMed ID: 2713848
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pyrazofurin inhibition of purine biosynthesis via 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate formyltransferase.
    Worzalla JF; Sweeney MJ
    Cancer Res; 1980 May; 40(5):1482-5. PubMed ID: 7370986
    [No Abstract]   [Full Text] [Related]  

  • 3. Antifolates induce primary inhibition of the de novo purine pathway prior to 5-aminoimidazole-4-carboxamide ribotide transformylase in leukemia cells.
    Lyons SD; Christopherson RI
    Biochem Int; 1991 May; 24(1):187-97. PubMed ID: 1768258
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Radioassay of bifunctional 5-aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase by thin-layer chromatography.
    Szabados E; Christopherson RI
    Anal Biochem; 1994 Sep; 221(2):401-4. PubMed ID: 7810885
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 5-Aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase from human CCRF-CEM leukemia cells: purification, pH dependence, and inhibitors.
    Szabados E; Hindmarsh EJ; Phillips L; Duggleby RG; Christopherson RI
    Biochemistry; 1994 Nov; 33(47):14237-45. PubMed ID: 7947835
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of pyrimidine biosynthesis in cultured L1210 cells by 3-deazauridine.
    Karle JM; Cysyk RL
    Biochem Pharmacol; 1984 Dec; 33(23):3739-42. PubMed ID: 6095859
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synergistic effect of purine derivatives on the toxicity of pyrazofurin and 6-azauridine towards cultured mammalian cells.
    Gupta RS; Moffat MR
    J Cell Physiol; 1982 Jun; 111(3):291-4. PubMed ID: 6178748
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytotoxic effects of inhibitors of de novo pyrimidine biosynthesis upon Plasmodium falciparum.
    Seymour KK; Lyons SD; Phillips L; Rieckmann KH; Christopherson RI
    Biochemistry; 1994 May; 33(17):5268-74. PubMed ID: 7909690
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chromatographic analysis of purine precursors in mouse L1210 leukemia.
    Sant ME; Poiner A; Harsanyi MC; Lyons SD; Christopherson RI
    Anal Biochem; 1989 Oct; 182(1):121-8. PubMed ID: 2604037
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cytotoxic effects of dihydroorotase inhibitors upon human CCRF-CEM leukemia.
    Brooke J; Szabados E; Lyons SD; Goodridge RJ; Harsanyi MC; Poiner A; Christopherson RI
    Cancer Res; 1990 Dec; 50(24):7793-8. PubMed ID: 1979249
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Uridine and cytidine metabolism following inhibition of de novo pyrimidine synthesis by pyrazofurin.
    Cadman E; Benz C
    Biochim Biophys Acta; 1980 Oct; 609(3):372-82. PubMed ID: 7437431
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of acivicin and dichloroallyl lawsone upon pyrimidine biosynthesis in mouse L1210 leukemia cells.
    Kemp AJ; Lyons SD; Christopherson RI
    J Biol Chem; 1986 Nov; 261(32):14891-5. PubMed ID: 3771555
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alteration in de novo pyrimidine biosynthesis during uridine reversal of pyrazofurin-inhibited DNA synthesis.
    Ringer DP; Howell BA; Etheredge JL
    J Biochem Toxicol; 1991; 6(1):19-27. PubMed ID: 1880786
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of N-[4-[5-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-2-(2,2,2-trifluoroacetyl)pentyl]benzoyl]-L-glutamic acid as a potential inhibitor of GAR Tfase and the de novo purine biosynthetic pathway.
    Cheng H; Hwang I; Chong Y; Tavassoli A; Webb ME; Zhang Y; Wilson IA; Benkovic SJ; Boger DL
    Bioorg Med Chem; 2005 May; 13(10):3593-9. PubMed ID: 15848772
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Relationship between the catalytic sites of human bifunctional IMP synthase.
    Szabados E; Christopherson RI
    Int J Biochem Cell Biol; 1998 Aug; 30(8):933-42. PubMed ID: 9744084
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human AICAR transformylase: role of the 4-carboxamide of AICAR in binding and catalysis.
    Wall M; Shim JH; Benkovic SJ
    Biochemistry; 2000 Sep; 39(37):11303-11. PubMed ID: 10985775
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The anti-inflammatory mechanism of sulfasalazine is related to adenosine release at inflamed sites.
    Gadangi P; Longaker M; Naime D; Levin RI; Recht PA; Montesinos MC; Buckley MT; Carlin G; Cronstein BN
    J Immunol; 1996 Mar; 156(5):1937-41. PubMed ID: 8596047
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of 3-deazauridine on the metabolism, toxicity, and antitumor activity of azacitidine in mice bearing L1210 leukemia sensitive and resistant to cytarabine.
    Li ZR; Campbell J; Rustum YM
    Cancer Treat Rep; 1983 Jun; 67(6):547-54. PubMed ID: 6190558
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors.
    Li C; Xu L; Wolan DW; Wilson IA; Olson AJ
    J Med Chem; 2004 Dec; 47(27):6681-90. PubMed ID: 15615517
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural insights into the human and avian IMP cyclohydrolase mechanism via crystal structures with the bound XMP inhibitor.
    Wolan DW; Cheong CG; Greasley SE; Wilson IA
    Biochemistry; 2004 Feb; 43(5):1171-83. PubMed ID: 14756553
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.