BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

124 related articles for article (PubMed ID: 27139467)

  • 1. Quinolone Amides as Antitrypanosomal Lead Compounds with In Vivo Activity.
    Hiltensperger G; Hecht N; Kaiser M; Rybak JC; Hoerst A; Dannenbauer N; Müller-Buschbaum K; Bruhn H; Esch H; Lehmann L; Meinel L; Holzgrabe U
    Antimicrob Agents Chemother; 2016 Aug; 60(8):4442-52. PubMed ID: 27139467
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fluorine walk: The impact of fluorine in quinolone amides on their activity against African sleeping sickness.
    Berninger M; Erk C; Fuß A; Skaf J; Al-Momani E; Israel I; Raschig M; Güntzel P; Samnick S; Holzgrabe U
    Eur J Med Chem; 2018 May; 152():377-391. PubMed ID: 29742443
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel S-adenosylmethionine decarboxylase inhibitors for the treatment of human African trypanosomiasis.
    Barker RH; Liu H; Hirth B; Celatka CA; Fitzpatrick R; Xiang Y; Willert EK; Phillips MA; Kaiser M; Bacchi CJ; Rodriguez A; Yarlett N; Klinger JD; Sybertz E
    Antimicrob Agents Chemother; 2009 May; 53(5):2052-8. PubMed ID: 19289530
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antitrypanosomal Chloronitrobenzamides.
    Carrillo AK; Kadayat TM; Hwang JY; Chen Y; Zhu F; Holbrook G; Gillingwater K; Connelly MC; Yang L; Kaiser M; Guy RK
    J Med Chem; 2024 Mar; 67(5):3437-3447. PubMed ID: 38363074
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A new nonpolar N-hydroxy imidazoline lead compound with improved activity in a murine model of late-stage Trypanosoma brucei brucei infection is not cross-resistant with diamidines.
    Ríos Martínez CH; Miller F; Ganeshamoorthy K; Glacial F; Kaiser M; de Koning HP; Eze AA; Lagartera L; Herraiz T; Dardonville C
    Antimicrob Agents Chemother; 2015 Feb; 59(2):890-904. PubMed ID: 25421467
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antitrypanosomal activity of fexinidazole, a new oral nitroimidazole drug candidate for treatment of sleeping sickness.
    Kaiser M; Bray MA; Cal M; Bourdin Trunz B; Torreele E; Brun R
    Antimicrob Agents Chemother; 2011 Dec; 55(12):5602-8. PubMed ID: 21911566
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and structure-activity relationships of new quinolone-type molecules against Trypanosoma brucei.
    Hiltensperger G; Jones NG; Niedermeier S; Stich A; Kaiser M; Jung J; Puhl S; Damme A; Braunschweig H; Meinel L; Engstler M; Holzgrabe U
    J Med Chem; 2012 Mar; 55(6):2538-48. PubMed ID: 22376072
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and biological evaluations of quinolone amides against African trypanosomiasis with improved solubility.
    Weinmann J; Kirchner L; Engstler M; Meinel L; Holzgrabe U
    Eur J Med Chem; 2023 Mar; 250():115176. PubMed ID: 36805945
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New heterocyclic compounds: Synthesis and antitrypanosomal properties.
    Pomel S; Dubar F; Forge D; Loiseau PM; Biot C
    Bioorg Med Chem; 2015 Aug; 23(16):5168-74. PubMed ID: 25835356
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vitro and in vivo evaluation of the antitrypanosomal activity of fractions of Holarrhena africana.
    Nwodo NJ; Brun R; Osadebe PO
    J Ethnopharmacol; 2007 Sep; 113(3):556-9. PubMed ID: 17728085
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 6-Arylpyrazine-2-carboxamides: A New Core for Trypanosoma brucei Inhibitors.
    Rahmani R; Ban K; Jones AJ; Ferrins L; Ganame D; Sykes ML; Avery VM; White KL; Ryan E; Kaiser M; Charman SA; Baell JB
    J Med Chem; 2015 Sep; 58(17):6753-65. PubMed ID: 26247439
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Trypanocidal activity of piperazine-linked bisbenzamidines and bisbenzamidoxime, an orally active prodrug.
    Huang TL; Bacchi CJ; Kode NR; Zhang Q; Wang G; Yartlet N; Rattendi D; Londono I; Mazumder L; Vanden Eynde JJ; Mayence A; Donkor IO
    Int J Antimicrob Agents; 2007 Dec; 30(6):555-61. PubMed ID: 17920820
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evaluating the impact of targeting livestock for the prevention of human and animal trypanosomiasis, at village level, in districts newly affected with T. b. rhodesiense in Uganda.
    Hamill L; Picozzi K; Fyfe J; von Wissmann B; Wastling S; Wardrop N; Selby R; Acup CA; Bardosh KL; Muhanguzi D; Kabasa JD; Waiswa C; Welburn SC
    Infect Dis Poverty; 2017 Feb; 6(1):16. PubMed ID: 28162093
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antitrypanosomal isothiocyanate and thiocarbamate glycosides from Moringa peregrina.
    Ayyari M; Salehi P; Ebrahimi SN; Zimmermann S; Portmann L; Krauth-Siegel RL; Kaiser M; Brun R; Rezadoost H; Rezazadeh S; Hamburger M
    Planta Med; 2014 Jan; 80(1):86-9. PubMed ID: 24310210
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antitrypanosomal activity of 1,2-dihydroquinolin-6-ols and their ester derivatives.
    Fotie J; Kaiser M; Delfín DA; Manley J; Reid CS; Paris JM; Wenzler T; Maes L; Mahasenan KV; Li C; Werbovetz KA
    J Med Chem; 2010 Feb; 53(3):966-82. PubMed ID: 20047276
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activity of extracts and naphthoquinones from Kigelia pinnata against Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense.
    Moideen SV; Houghton PJ; Rock P; Croft SL; Aboagye-Nyame F
    Planta Med; 1999 Aug; 65(6):536-40. PubMed ID: 10483374
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis.
    Ferrins L; Rahmani R; Sykes ML; Jones AJ; Avery VM; Teston E; Almohaywi B; Yin J; Smith J; Hyland C; White KL; Ryan E; Campbell M; Charman SA; Kaiser M; Baell JB
    Eur J Med Chem; 2013 Aug; 66():450-65. PubMed ID: 23831695
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of novel orally bioavailable oxaborole 6-carboxamides that demonstrate cure in a murine model of late-stage central nervous system african trypanosomiasis.
    Nare B; Wring S; Bacchi C; Beaudet B; Bowling T; Brun R; Chen D; Ding C; Freund Y; Gaukel E; Hussain A; Jarnagin K; Jenks M; Kaiser M; Mercer L; Mejia E; Noe A; Orr M; Parham R; Plattner J; Randolph R; Rattendi D; Rewerts C; Sligar J; Yarlett N; Don R; Jacobs R
    Antimicrob Agents Chemother; 2010 Oct; 54(10):4379-88. PubMed ID: 20660666
    [TBL] [Abstract][Full Text] [Related]  

  • 19. From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds.
    Venkatraj M; Ariën KK; Heeres J; Joossens J; Dirié B; Lyssens S; Michiels J; Cos P; Lewi PJ; Vanham G; Maes L; Van der Veken P; Augustyns K
    Bioorg Med Chem; 2014 Oct; 22(19):5241-8. PubMed ID: 25199582
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of antitrypanosomal activity of Pterocarpus santalinoides L'H'erit ex DC hydroethanol leaf extract in rats experimentally infected with Trypanosoma brucei.
    Obi CF; Nzeakor TA; Okpala MI; Ezeh IO; Nwobi LG; Omeje MO; Ezeokonkwo RC
    J Ethnopharmacol; 2019 Oct; 243():112085. PubMed ID: 31306694
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.