These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 27144341)

  • 1. Obatoclax kills anaplastic thyroid cancer cells by inducing lysosome neutralization and necrosis.
    Champa D; Orlacchio A; Patel B; Ranieri M; Shemetov AA; Verkhusha VV; Cuervo AM; Di Cristofano A
    Oncotarget; 2016 Jun; 7(23):34453-71. PubMed ID: 27144341
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells.
    Yu L; Wu WK; Gu C; Zhong D; Zhao X; Kong Y; Lin Q; Chan MT; Zhou Z; Liu S
    Oncotarget; 2016 Mar; 7(12):14693-707. PubMed ID: 26910910
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer.
    Wei WJ; Sun ZK; Shen CT; Song HJ; Zhang XY; Qiu ZL; Luo QY
    Theranostics; 2017; 7(4):987-1001. PubMed ID: 28382170
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Obatoclax overcomes resistance to cell death in aggressive thyroid carcinomas by countering Bcl2a1 and Mcl1 overexpression.
    Champa D; Russo MA; Liao XH; Refetoff S; Ghossein RA; Di Cristofano A
    Endocr Relat Cancer; 2014 Oct; 21(5):755-67. PubMed ID: 25012986
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling.
    Koehler BC; Jassowicz A; Scherr AL; Lorenz S; Radhakrishnan P; Kautz N; Elssner C; Weiss J; Jaeger D; Schneider M; Schulze-Bergkamen H
    BMC Cancer; 2015 Nov; 15():919. PubMed ID: 26585594
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The BH3 Mimetic Obatoclax Accumulates in Lysosomes and Causes Their Alkalinization.
    Stamelos VA; Fisher N; Bamrah H; Voisey C; Price JC; Farrell WE; Redman CW; Richardson A
    PLoS One; 2016; 11(3):e0150696. PubMed ID: 26950068
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Obatoclax induces Atg7-dependent autophagy independent of beclin-1 and BAX/BAK.
    McCoy F; Hurwitz J; McTavish N; Paul I; Barnes C; O'Hagan B; Odrzywol K; Murray J; Longley D; McKerr G; Fennell DA
    Cell Death Dis; 2010 Dec; 1(12):e108. PubMed ID: 21368880
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Obatoclax, a Pan-BCL-2 Inhibitor, Downregulates Survivin to Induce Apoptosis in Human Colorectal Carcinoma Cells Via Suppressing WNT/β-catenin Signaling.
    Or CR; Huang CW; Chang CC; Lai YC; Chen YJ; Chang CC
    Int J Mol Sci; 2020 Mar; 21(5):. PubMed ID: 32150830
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synergic Induction of Autophagic Cell Death in Anaplastic Thyroid Carcinoma.
    Wächter S; Knauff F; Roth S; Keber C; Holzer K; Manoharan J; Maurer E; Bartsch DK; Di Fazio P
    Cancer Invest; 2023 Apr; 41(4):405-421. PubMed ID: 36811581
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Obatoclax induces Beclin 1- and ATG5-dependent apoptosis and autophagy in adenoid cystic carcinoma cells.
    Liang LZ; Ma B; Liang YJ; Liu HC; Zhang TH; Zheng GS; Su YX; Liao GQ
    Oral Dis; 2015 May; 21(4):470-7. PubMed ID: 25482163
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Obatoclax Inhibits Alphavirus Membrane Fusion by Neutralizing the Acidic Environment of Endocytic Compartments.
    Varghese FS; Rausalu K; Hakanen M; Saul S; Kümmerer BM; Susi P; Merits A; Ahola T
    Antimicrob Agents Chemother; 2017 Mar; 61(3):. PubMed ID: 27993855
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The pan-Bcl-2 blocker obatoclax promotes the expression of Puma, Noxa, and Bim mRNA and induces apoptosis in neoplastic mast cells.
    Peter B; Cerny-Reiterer S; Hadzijusufovic E; Schuch K; Stefanzl G; Eisenwort G; Gleixner KV; Hoermann G; Mayerhofer M; Kundi M; Baumgartner S; Sperr WR; Pickl WF; Willmann M; Valent P
    J Leukoc Biol; 2014 Jan; 95(1):95-104. PubMed ID: 24052572
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Myricetin Induces Apoptosis of Human Anaplastic Thyroid Cancer Cells
    Jo S; Ha TK; Han SH; Kim ME; Jung I; Lee HW; Bae SK; Lee JS
    Anticancer Res; 2017 Apr; 37(4):1705-1710. PubMed ID: 28373432
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective targeting of BCL6 induces oncogene addiction switching to BCL2 in B-cell lymphoma.
    Dupont T; Yang SN; Patel J; Hatzi K; Malik A; Tam W; Martin P; Leonard J; Melnick A; Cerchietti L
    Oncotarget; 2016 Jan; 7(3):3520-32. PubMed ID: 26657288
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Obatoclax, a Pan-BCL-2 Inhibitor, Targets Cyclin D1 for Degradation to Induce Antiproliferation in Human Colorectal Carcinoma Cells.
    Or CR; Chang Y; Lin WC; Lee WC; Su HL; Cheung MW; Huang CP; Ho C; Chang CC
    Int J Mol Sci; 2016 Dec; 18(1):. PubMed ID: 28035994
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis.
    Sadowski SM; Boufraqech M; Zhang L; Mehta A; Kapur P; Zhang Y; Li Z; Shen M; Kebebew E
    Oncotarget; 2015 Jul; 6(20):18038-49. PubMed ID: 25945839
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The pan-Bcl-2 inhibitor obatoclax promotes differentiation and apoptosis of acute myeloid leukemia cells.
    Opydo-Chanek M; Cichoń I; Rak A; Kołaczkowska E; Mazur L
    Invest New Drugs; 2020 Dec; 38(6):1664-1676. PubMed ID: 32367199
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tolfenamic acid induces apoptosis and growth inhibition in anaplastic thyroid cancer: Involvement of nonsteroidal anti-inflammatory drug-activated gene-1 expression and intracellular reactive oxygen species generation.
    Chang JW; Kang SU; Choi JW; Shin YS; Baek SJ; Lee SH; Kim CH
    Free Radic Biol Med; 2014 Feb; 67():115-30. PubMed ID: 24216474
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Single-agent obatoclax (GX15-070) potently induces apoptosis and pro-survival autophagy in head and neck squamous cell carcinoma cells.
    Yazbeck VY; Li C; Grandis JR; Zang Y; Johnson DE
    Oral Oncol; 2014 Feb; 50(2):120-7. PubMed ID: 24216166
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of autophagy in the resistance to tumour necrosis factor-related apoptosis-inducing ligand-induced apoptosis in papillary and anaplastic thyroid cancer cells.
    Jin SM; Jang HW; Sohn SY; Kim NK; Joung JY; Cho YY; Kim SW; Chung JH
    Endocrine; 2014 Mar; 45(2):256-62. PubMed ID: 23821365
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.