BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

2839 related articles for article (PubMed ID: 27147665)

  • 1. Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration.
    Qin H; Buckley JA; Li X; Liu Y; Fox TH; Meares GP; Yu H; Yan Z; Harms AS; Li Y; Standaert DG; Benveniste EN
    J Neurosci; 2016 May; 36(18):5144-59. PubMed ID: 27147665
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson's disease.
    Williams GP; Schonhoff AM; Jurkuvenaite A; Thome AD; Standaert DG; Harms AS
    J Neuroinflammation; 2018 Aug; 15(1):244. PubMed ID: 30165873
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Suppression of the JAK/STAT Pathway Inhibits Neuroinflammation in the Line 61-PFF Mouse Model of Parkinson's Disease.
    Hong H; Wang Y; Menard M; Buckley J; Zhou L; Volpicelli-Daley L; Standaert D; Qin H; Benveniste E
    Res Sq; 2024 May; ():. PubMed ID: 38766241
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease.
    Gordon R; Singh N; Lawana V; Ghosh A; Harischandra DS; Jin H; Hogan C; Sarkar S; Rokad D; Panicker N; Anantharam V; Kanthasamy AG; Kanthasamy A
    Neurobiol Dis; 2016 Sep; 93():96-114. PubMed ID: 27151770
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis.
    Liu Y; Holdbrooks AT; De Sarno P; Rowse AL; Yanagisawa LL; McFarland BC; Harrington LE; Raman C; Sabbaj S; Benveniste EN; Qin H
    J Immunol; 2014 Jan; 192(1):59-72. PubMed ID: 24323580
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The involvement of JAK/STAT signaling pathway in the treatment of Parkinson's disease.
    Lashgari NA; Roudsari NM; Momtaz S; Sathyapalan T; Abdolghaffari AH; Sahebkar A
    J Neuroimmunol; 2021 Dec; 361():577758. PubMed ID: 34739911
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cx3cr1-deficiency exacerbates alpha-synuclein-A53T induced neuroinflammation and neurodegeneration in a mouse model of Parkinson's disease.
    Castro-Sánchez S; García-Yagüe ÁJ; López-Royo T; Casarejos M; Lanciego JL; Lastres-Becker I
    Glia; 2018 Aug; 66(8):1752-1762. PubMed ID: 29624735
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration.
    Harms AS; Cao S; Rowse AL; Thome AD; Li X; Mangieri LR; Cron RQ; Shacka JJ; Raman C; Standaert DG
    J Neurosci; 2013 Jun; 33(23):9592-600. PubMed ID: 23739956
    [TBL] [Abstract][Full Text] [Related]  

  • 9. T cell infiltration and upregulation of MHCII in microglia leads to accelerated neuronal loss in an α-synuclein rat model of Parkinson's disease.
    Subbarayan MS; Hudson C; Moss LD; Nash KR; Bickford PC
    J Neuroinflammation; 2020 Aug; 17(1):242. PubMed ID: 32799878
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Allelic difference in Mhc2ta confers altered microglial activation and susceptibility to α-synuclein-induced dopaminergic neurodegeneration.
    Jimenez-Ferrer I; Jewett M; Tontanahal A; Romero-Ramos M; Swanberg M
    Neurobiol Dis; 2017 Oct; 106():279-290. PubMed ID: 28736195
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
    Duffy MF; Collier TJ; Patterson JR; Kemp CJ; Luk KC; Tansey MG; Paumier KL; Kanaan NM; Fischer DL; Polinski NK; Barth OL; Howe JW; Vaikath NN; Majbour NK; El-Agnaf OMA; Sortwell CE
    J Neuroinflammation; 2018 May; 15(1):129. PubMed ID: 29716614
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease.
    Gao HM; Zhang F; Zhou H; Kam W; Wilson B; Hong JS
    Environ Health Perspect; 2011 Jun; 119(6):807-14. PubMed ID: 21245015
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabotropic glutamate receptor 5 inhibits α-synuclein-induced microglia inflammation to protect from neurotoxicity in Parkinson's disease.
    Zhang YN; Fan JK; Gu L; Yang HM; Zhan SQ; Zhang H
    J Neuroinflammation; 2021 Jan; 18(1):23. PubMed ID: 33461598
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Age-dependent neurodegeneration and neuroinflammation in a genetic A30P/A53T double-mutated α-synuclein mouse model of Parkinson's disease.
    Rauschenberger L; Behnke J; Grotemeyer A; Knorr S; Volkmann J; Ip CW
    Neurobiol Dis; 2022 Sep; 171():105798. PubMed ID: 35750147
    [TBL] [Abstract][Full Text] [Related]  

  • 15. FcγRIIB mediates the inhibitory effect of aggregated α-synuclein on microglial phagocytosis.
    Choi YR; Kang SJ; Kim JM; Lee SJ; Jou I; Joe EH; Park SM
    Neurobiol Dis; 2015 Nov; 83():90-9. PubMed ID: 26342897
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacological inhibition of CSF1R by GW2580 reduces microglial proliferation and is protective against neuroinflammation and dopaminergic neurodegeneration.
    Neal ML; Fleming SM; Budge KM; Boyle AM; Kim C; Alam G; Beier EE; Wu LJ; Richardson JR
    FASEB J; 2020 Jan; 34(1):1679-1694. PubMed ID: 31914683
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Microglia affect α-synuclein cell-to-cell transfer in a mouse model of Parkinson's disease.
    George S; Rey NL; Tyson T; Esquibel C; Meyerdirk L; Schulz E; Pierce S; Burmeister AR; Madaj Z; Steiner JA; Escobar Galvis ML; Brundin L; Brundin P
    Mol Neurodegener; 2019 Aug; 14(1):34. PubMed ID: 31419995
    [TBL] [Abstract][Full Text] [Related]  

  • 18. microRNA-155 Regulates Alpha-Synuclein-Induced Inflammatory Responses in Models of Parkinson Disease.
    Thome AD; Harms AS; Volpicelli-Daley LA; Standaert DG
    J Neurosci; 2016 Feb; 36(8):2383-90. PubMed ID: 26911687
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Minimally Toxic Dose of Lipopolysaccharide and α-Synuclein Oligomer Elicit Synergistic Dopaminergic Neurodegeneration: Role and Mechanism of Microglial NOX2 Activation.
    Zhang W; Gao JH; Yan ZF; Huang XY; Guo P; Sun L; Liu Z; Hu Y; Zuo LJ; Yu SY; Cao CJ; Wang XM; Hong JS
    Mol Neurobiol; 2018 Jan; 55(1):619-632. PubMed ID: 27975175
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Neuroinflammation in Parkinson's Disease and its Treatment Opportunities.
    Çınar E; Tel BC; Şahin G
    Balkan Med J; 2022 Sep; 39(5):318-333. PubMed ID: 36036436
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 142.