BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

449 related articles for article (PubMed ID: 27148972)

  • 1. Overexpression of Latent TGFβ Binding Protein 4 in Muscle Ameliorates Muscular Dystrophy through Myostatin and TGFβ.
    Lamar KM; Bogdanovich S; Gardner BB; Gao QQ; Miller T; Earley JU; Hadhazy M; Vo AH; Wren L; Molkentin JD; McNally EM
    PLoS Genet; 2016 May; 12(5):e1006019. PubMed ID: 27148972
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A GDF11/myostatin inhibitor, GDF11 propeptide-Fc, increases skeletal muscle mass and improves muscle strength in dystrophic mdx mice.
    Jin Q; Qiao C; Li J; Xiao B; Li J; Xiao X
    Skelet Muscle; 2019 May; 9(1):16. PubMed ID: 31133057
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The pan HDAC inhibitor Givinostat improves muscle function and histological parameters in two Duchenne muscular dystrophy murine models expressing different haplotypes of the LTBP4 gene.
    Licandro SA; Crippa L; Pomarico R; Perego R; Fossati G; Leoni F; Steinkühler C
    Skelet Muscle; 2021 Jul; 11(1):19. PubMed ID: 34294164
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Anti-latent TGFβ binding protein 4 antibody improves muscle function and reduces muscle fibrosis in muscular dystrophy.
    Demonbreun AR; Fallon KS; Oosterbaan CC; Vaught LA; Reiser NL; Bogdanovic E; Velez MP; Salamone IM; Page PGT; Hadhazy M; Quattrocelli M; Barefield DY; Wood LD; Gonzalez JP; Morris C; McNally EM
    Sci Transl Med; 2021 Sep; 13(610):eabf0376. PubMed ID: 34516828
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Non-Glycanated Biglycan and LTBP4: Leveraging the extracellular matrix for Duchenne Muscular Dystrophy therapeutics.
    Fallon JR; McNally EM
    Matrix Biol; 2018 Aug; 68-69():616-627. PubMed ID: 29481844
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting latent TGFβ release in muscular dystrophy.
    Ceco E; Bogdanovich S; Gardner B; Miller T; DeJesus A; Earley JU; Hadhazy M; Smith LR; Barton ER; Molkentin JD; McNally EM
    Sci Transl Med; 2014 Oct; 6(259):259ra144. PubMed ID: 25338755
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Outside in: The matrix as a modifier of muscular dystrophy.
    Quattrocelli M; Spencer MJ; McNally EM
    Biochim Biophys Acta Mol Cell Res; 2017 Mar; 1864(3):572-579. PubMed ID: 28011285
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys.
    St Andre M; Johnson M; Bansal PN; Wellen J; Robertson A; Opsahl A; Burch PM; Bialek P; Morris C; Owens J
    Skelet Muscle; 2017 Nov; 7(1):25. PubMed ID: 29121992
    [TBL] [Abstract][Full Text] [Related]  

  • 9. LTBP4 genotype predicts age of ambulatory loss in Duchenne muscular dystrophy.
    Flanigan KM; Ceco E; Lamar KM; Kaminoh Y; Dunn DM; Mendell JR; King WM; Pestronk A; Florence JM; Mathews KD; Finkel RS; Swoboda KJ; Gappmaier E; Howard MT; Day JW; McDonald C; McNally EM; Weiss RB;
    Ann Neurol; 2013 Apr; 73(4):481-8. PubMed ID: 23440719
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Spp1 (osteopontin) promotes TGFβ processing in fibroblasts of dystrophin-deficient muscles through matrix metalloproteinases.
    Kramerova I; Kumagai-Cresse C; Ermolova N; Mokhonova E; Marinov M; Capote J; Becerra D; Quattrocelli M; Crosbie RH; Welch E; McNally EM; Spencer MJ
    Hum Mol Genet; 2019 Oct; 28(20):3431-3442. PubMed ID: 31411676
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Long-range genomic regulators of THBS1 and LTBP4 modify disease severity in duchenne muscular dystrophy.
    Weiss RB; Vieland VJ; Dunn DM; Kaminoh Y; Flanigan KM;
    Ann Neurol; 2018 Aug; 84(2):234-245. PubMed ID: 30014611
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice.
    Heydemann A; Ceco E; Lim JE; Hadhazy M; Ryder P; Moran JL; Beier DR; Palmer AA; McNally EM
    J Clin Invest; 2009 Dec; 119(12):3703-12. PubMed ID: 19884661
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Follistatin-based ligand trap ACE-083 induces localized hypertrophy of skeletal muscle with functional improvement in models of neuromuscular disease.
    Pearsall RS; Davies MV; Cannell M; Li J; Widrick J; Mulivor AW; Wallner S; Troy ME; Spaits M; Liharska K; Sako D; Castonguay R; Keates S; Grinberg AV; Suragani RNVS; Kumar R
    Sci Rep; 2019 Aug; 9(1):11392. PubMed ID: 31388039
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Muscle-bone interactions in dystrophin-deficient and myostatin-deficient mice.
    Montgomery E; Pennington C; Isales CM; Hamrick MW
    Anat Rec A Discov Mol Cell Evol Biol; 2005 Sep; 286(1):814-22. PubMed ID: 16078270
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Treatment with rGDF11 does not improve the dystrophic muscle pathology of mdx mice.
    Rinaldi F; Zhang Y; Mondragon-Gonzalez R; Harvey J; Perlingeiro RCR
    Skelet Muscle; 2016; 6():21. PubMed ID: 27303621
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Myostatin inhibition by a follistatin-derived peptide ameliorates the pathophysiology of muscular dystrophy model mice.
    Tsuchida K
    Acta Myol; 2008 Jul; 27(1):14-8. PubMed ID: 19108572
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury.
    Quattrocelli M; Capote J; Ohiri JC; Warner JL; Vo AH; Earley JU; Hadhazy M; Demonbreun AR; Spencer MJ; McNally EM
    PLoS Genet; 2017 Oct; 13(10):e1007070. PubMed ID: 29065150
    [TBL] [Abstract][Full Text] [Related]  

  • 18. AMPK Activation Regulates LTBP4-Dependent TGF-β1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy.
    Juban G; Saclier M; Yacoub-Youssef H; Kernou A; Arnold L; Boisson C; Ben Larbi S; Magnan M; Cuvellier S; Théret M; Petrof BJ; Desguerre I; Gondin J; Mounier R; Chazaud B
    Cell Rep; 2018 Nov; 25(8):2163-2176.e6. PubMed ID: 30463013
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Systemic myostatin inhibition via liver-targeted gene transfer in normal and dystrophic mice.
    Morine KJ; Bish LT; Pendrak K; Sleeper MM; Barton ER; Sweeney HL
    PLoS One; 2010 Feb; 5(2):e9176. PubMed ID: 20161803
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Genotype-Specific Interaction of Latent TGFβ Binding Protein 4 with TGFβ.
    Lamar KM; Miller T; Dellefave-Castillo L; McNally EM
    PLoS One; 2016; 11(2):e0150358. PubMed ID: 26918958
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.