174 related articles for article (PubMed ID: 27149641)
1. Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo.
Yan J; Chen J; Zhang S; Hu J; Huang L; Li X
J Med Chem; 2016 Jun; 59(11):5264-83. PubMed ID: 27149641
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
Wang G; Li C; He L; Lei K; Wang F; Pu Y; Yang Z; Cao D; Ma L; Chen J; Sang Y; Liang X; Xiang M; Peng A; Wei Y; Chen L
Bioorg Med Chem; 2014 Apr; 22(7):2060-79. PubMed ID: 24629450
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and biological evaluation of pyridine-chalcone derivatives as novel microtubule-destabilizing agents.
Xu F; Li W; Shuai W; Yang L; Bi Y; Ma C; Yao H; Xu S; Zhu Z; Xu J
Eur J Med Chem; 2019 Jul; 173():1-14. PubMed ID: 30981112
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach.
Preti D; Romagnoli R; Rondanin R; Cacciari B; Hamel E; Balzarini J; Liekens S; Schols D; Estévez-Sarmiento F; Quintana J; Estévez F
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):1225-1238. PubMed ID: 30141353
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, biological evaluation and molecular docking studies of aminochalcone derivatives as potential anticancer agents by targeting tubulin colchicine binding site.
Wang G; Peng Z; Zhang J; Qiu J; Xie Z; Gong Z
Bioorg Chem; 2018 Aug; 78():332-340. PubMed ID: 29627654
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis, and biological evaluation of cyclic-indole derivatives as anti-tumor agents via the inhibition of tubulin polymerization.
Yan J; Hu J; An B; Huang L; Li X
Eur J Med Chem; 2017 Jan; 125():663-675. PubMed ID: 27721152
[TBL] [Abstract][Full Text] [Related]
7. YSL-12, a novel microtubule-destabilizing agent, exerts potent anti-tumor activity against colon cancer in vitro and in vivo.
Cai D; Qiu Z; Yao W; Liu Y; Huang H; Liao S; Luo Q; Xie L; Lin Z
Cancer Chemother Pharmacol; 2016 Jun; 77(6):1217-29. PubMed ID: 27107592
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells.
Romagnoli R; Prencipe F; Lopez-Cara LC; Oliva P; Baraldi S; Baraldi PG; Estévez-Sarmiento F; Quintana J; Estévez F
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):727-742. PubMed ID: 29620429
[TBL] [Abstract][Full Text] [Related]
9. Pt(IV) complexes conjugating with chalcone analogue as inhibitors of microtubule polymerization exhibited selective inhibition in human cancer cells.
Huang X; Huang R; Wang Z; Li L; Gou S; Liao Z; Wang H
Eur J Med Chem; 2018 Feb; 146():435-450. PubMed ID: 29407969
[TBL] [Abstract][Full Text] [Related]
10. Discovery of novel vinyl sulfone derivatives as anti-tumor agents with microtubule polymerization inhibitory and vascular disrupting activities.
Li W; Yin Y; Yao H; Shuai W; Sun H; Xu S; Liu J; Yao H; Zhu Z; Xu J
Eur J Med Chem; 2018 Sep; 157():1068-1080. PubMed ID: 30176537
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and bio-evaluation of indole-chalcone based benzopyrans as promising antiligase and antiproliferative agents.
Gupta S; Maurya P; Upadhyay A; Kushwaha P; Krishna S; Siddiqi MI; Sashidhara KV; Banerjee D
Eur J Med Chem; 2018 Jan; 143():1981-1996. PubMed ID: 29146133
[TBL] [Abstract][Full Text] [Related]
12. Development of Novel Bis(indolyl)-hydrazide-Hydrazone Derivatives as Potent Microtubule-Targeting Cytotoxic Agents against A549 Lung Cancer Cells.
Das Mukherjee D; Kumar NM; Tantak MP; Das A; Ganguli A; Datta S; Kumar D; Chakrabarti G
Biochemistry; 2016 May; 55(21):3020-35. PubMed ID: 27110637
[TBL] [Abstract][Full Text] [Related]
13. Synthesis of phenstatin/isocombretastatin-chalcone conjugates as potent tubulin polymerization inhibitors and mitochondrial apoptotic inducers.
Kamal A; Kumar GB; Vishnuvardhan MV; Shaik AB; Reddy VS; Mahesh R; Sayeeda IB; Kapure JS
Org Biomol Chem; 2015 Apr; 13(13):3963-81. PubMed ID: 25721862
[TBL] [Abstract][Full Text] [Related]
14. In vitro and in vivo anti-glioma activity of a chalcone-quinoxaline hybrid.
Loch-Neckel G; Bicca MA; Leal PC; Mascarello A; Siqueira JM; Calixto JB
Eur J Med Chem; 2015 Jan; 90():93-100. PubMed ID: 25461314
[TBL] [Abstract][Full Text] [Related]
15. Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors.
Cao D; Liu Y; Yan W; Wang C; Bai P; Wang T; Tang M; Wang X; Yang Z; Ma B; Ma L; Lei L; Wang F; Xu B; Zhou Y; Yang T; Chen L
J Med Chem; 2016 Jun; 59(12):5721-39. PubMed ID: 27213819
[TBL] [Abstract][Full Text] [Related]
16. Discovery of novel chalcone-dithiocarbamates as ROS-mediated apoptosis inducers by inhibiting catalase.
Fu DJ; Li JH; Yang JJ; Li P; Zhang YB; Liu S; Li ZR; Zhang SY
Bioorg Chem; 2019 May; 86():375-385. PubMed ID: 30763884
[TBL] [Abstract][Full Text] [Related]
17. Novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitor: synthesis, anti-invasive and anti-angiogenic properties.
Wang L; Chen G; Lu X; Wang S; Han S; Li Y; Ping G; Jiang X; Li H; Yang J; Wu C
Eur J Med Chem; 2015 Jan; 89():88-97. PubMed ID: 25462229
[TBL] [Abstract][Full Text] [Related]
18. Synthesis of different heterocycles-linked chalcone conjugates as cytotoxic agents and tubulin polymerization inhibitors.
Shankaraiah N; Nekkanti S; Brahma UR; Praveen Kumar N; Deshpande N; Prasanna D; Senwar KR; Jaya Lakshmi U
Bioorg Med Chem; 2017 Sep; 25(17):4805-4816. PubMed ID: 28774575
[TBL] [Abstract][Full Text] [Related]
19. Platinum(IV) complexes conjugated with chalcone analogs as dual targeting anticancer agents: In vitro and in vivo studies.
Huang X; Liu Z; Wang M; Yin X; Wang Y; Dai L; Wang H
Bioorg Chem; 2020 Dec; 105():104430. PubMed ID: 33171407
[TBL] [Abstract][Full Text] [Related]
20. Synthesis, in vitro and in vivo evaluation of new hybrids of millepachine and phenstatin as potent tubulin polymerization inhibitors.
An B; Zhang S; Yan J; Huang L; Li X
Org Biomol Chem; 2017 Jan; 15(4):852-862. PubMed ID: 28009925
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
