BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

372 related articles for article (PubMed ID: 27151974)

  • 1. Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis.
    Inoue D; Bradley RK; Abdel-Wahab O
    Genes Dev; 2016 May; 30(9):989-1001. PubMed ID: 27151974
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Frequent pathway mutations of splicing machinery in myelodysplasia.
    Yoshida K; Sanada M; Shiraishi Y; Nowak D; Nagata Y; Yamamoto R; Sato Y; Sato-Otsubo A; Kon A; Nagasaki M; Chalkidis G; Suzuki Y; Shiosaka M; Kawahata R; Yamaguchi T; Otsu M; Obara N; Sakata-Yanagimoto M; Ishiyama K; Mori H; Nolte F; Hofmann WK; Miyawaki S; Sugano S; Haferlach C; Koeffler HP; Shih LY; Haferlach T; Chiba S; Nakauchi H; Miyano S; Ogawa S
    Nature; 2011 Sep; 478(7367):64-9. PubMed ID: 21909114
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis.
    Makishima H; Visconte V; Sakaguchi H; Jankowska AM; Abu Kar S; Jerez A; Przychodzen B; Bupathi M; Guinta K; Afable MG; Sekeres MA; Padgett RA; Tiu RV; Maciejewski JP
    Blood; 2012 Apr; 119(14):3203-10. PubMed ID: 22323480
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins.
    Lee SC; Dvinge H; Kim E; Cho H; Micol JB; Chung YR; Durham BH; Yoshimi A; Kim YJ; Thomas M; Lobry C; Chen CW; Pastore A; Taylor J; Wang X; Krivtsov A; Armstrong SA; Palacino J; Buonamici S; Smith PG; Bradley RK; Abdel-Wahab O
    Nat Med; 2016 Jun; 22(6):672-8. PubMed ID: 27135740
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Spliceosome mutations exhibit specific associations with epigenetic modifiers and proto-oncogenes mutated in myelodysplastic syndrome.
    Mian SA; Smith AE; Kulasekararaj AG; Kizilors A; Mohamedali AM; Lea NC; Mitsopoulos K; Ford K; Nasser E; Seidl T; Mufti GJ
    Haematologica; 2013 Jul; 98(7):1058-66. PubMed ID: 23300180
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Emerging roles of the spliceosomal machinery in myelodysplastic syndromes and other hematological disorders.
    Visconte V; Makishima H; Maciejewski JP; Tiu RV
    Leukemia; 2012 Dec; 26(12):2447-54. PubMed ID: 22678168
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Modeling human RNA spliceosome mutations in the mouse: not all mice were created equal.
    Xu JJ; Smeets MF; Tan SY; Wall M; Purton LE; Walkley CR
    Exp Hematol; 2019 Feb; 70():10-23. PubMed ID: 30408513
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The prognostic impact of mutations in spliceosomal genes for myelodysplastic syndrome patients without ring sideroblasts.
    Kang MG; Kim HR; Seo BY; Lee JH; Choi SY; Kim SH; Shin JH; Suh SP; Ahn JS; Shin MG
    BMC Cancer; 2015 Jun; 15():484. PubMed ID: 26115659
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutations in the Spliceosomal Machinery Genes SRSF2, U2AF1, and ZRSR2 and Response to Decitabine in Myelodysplastic Syndrome.
    Hong JY; Seo JY; Kim SH; Jung HA; Park S; Kim K; Jung CW; Kim JS; Park JS; Kim HJ; Jang JH
    Anticancer Res; 2015 May; 35(5):3081-9. PubMed ID: 25964599
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recurrent SRSF2 mutations in MDS affect both splicing and NMD.
    Rahman MA; Lin KT; Bradley RK; Abdel-Wahab O; Krainer AR
    Genes Dev; 2020 Mar; 34(5-6):413-427. PubMed ID: 32001512
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Point mutations of genes encoding proteins involvedin RNA splicing in patients with myelodysplastic syndromes].
    Barańska M; Czerwińska-Rybak J; Gil L; Komarnicki M
    Pol Merkur Lekarski; 2015 Jan; 38(223):5-10. PubMed ID: 25763580
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Disease-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1.
    Zhang J; Ali AM; Lieu YK; Liu Z; Gao J; Rabadan R; Raza A; Mukherjee S; Manley JL
    Mol Cell; 2019 Oct; 76(1):82-95.e7. PubMed ID: 31474574
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutations in spliceosome genes and therapeutic opportunities in myeloid malignancies.
    Taylor J; Lee SC
    Genes Chromosomes Cancer; 2019 Dec; 58(12):889-902. PubMed ID: 31334570
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations.
    Lee SC; North K; Kim E; Jang E; Obeng E; Lu SX; Liu B; Inoue D; Yoshimi A; Ki M; Yeo M; Zhang XJ; Kim MK; Cho H; Chung YR; Taylor J; Durham BH; Kim YJ; Pastore A; Monette S; Palacino J; Seiler M; Buonamici S; Smith PG; Ebert BL; Bradley RK; Abdel-Wahab O
    Cancer Cell; 2018 Aug; 34(2):225-241.e8. PubMed ID: 30107174
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia.
    Shiozawa Y; Malcovati L; Gallì A; Sato-Otsubo A; Kataoka K; Sato Y; Watatani Y; Suzuki H; Yoshizato T; Yoshida K; Sanada M; Makishima H; Shiraishi Y; Chiba K; Hellström-Lindberg E; Miyano S; Ogawa S; Cazzola M
    Nat Commun; 2018 Sep; 9(1):3649. PubMed ID: 30194306
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rare and private spliceosomal gene mutations drive partial, complete, and dual phenocopies of hotspot alterations.
    Pangallo J; Kiladjian JJ; Cassinat B; Renneville A; Taylor J; Polaski JT; North K; Abdel-Wahab O; Bradley RK
    Blood; 2020 Mar; 135(13):1032-1043. PubMed ID: 31961934
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SRSF2 Is Essential for Hematopoiesis, and Its Myelodysplastic Syndrome-Related Mutations Dysregulate Alternative Pre-mRNA Splicing.
    Komeno Y; Huang YJ; Qiu J; Lin L; Xu Y; Zhou Y; Chen L; Monterroza DD; Li H; DeKelver RC; Yan M; Fu XD; Zhang DE
    Mol Cell Biol; 2015 Sep; 35(17):3071-82. PubMed ID: 26124281
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SF3B1 mutant myelodysplastic syndrome: Recent advances.
    Pellagatti A; Boultwood J
    Adv Biol Regul; 2021 Jan; 79():100776. PubMed ID: 33358369
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutational analysis of splicing machinery genes SF3B1, U2AF1 and SRSF2 in myelodysplasia and other common tumors.
    Je EM; Yoo NJ; Kim YJ; Kim MS; Lee SH
    Int J Cancer; 2013 Jul; 133(1):260-5. PubMed ID: 23280334
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Clinicopathologic characterisation of myeloid neoplasms with concurrent spliceosome mutations and myeloproliferative-neoplasm-associated mutations.
    Liu YC; Illar GM; Bailey NG
    J Clin Pathol; 2020 Nov; 73(11):728-736. PubMed ID: 32217616
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.