These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

397 related articles for article (PubMed ID: 27158139)

  • 1. Cyclooxygenase-2 and 15-lipoxygenase inhibition, synthesis, anti-inflammatory activity and ulcer liability of new celecoxib analogues: Determination of region-specific pyrazole ring formation by NOESY.
    Abdelall EKA; Lamie PF; Ali WAM
    Bioorg Med Chem Lett; 2016 Jun; 26(12):2893-2899. PubMed ID: 27158139
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of new thiazolo-celecoxib analogues as dual cyclooxygenase-2/15-lipoxygenase inhibitors: Determination of regio-specific different pyrazole cyclization by 2D NMR.
    Abdelall EK; Kamel GM
    Eur J Med Chem; 2016 Aug; 118():250-8. PubMed ID: 27131067
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New 1,2,4-triazole/pyrazole hybrids linked to oxime moiety as nitric oxide donor celecoxib analogs: Synthesis, cyclooxygenase inhibition anti-inflammatory, ulcerogenicity, anti-proliferative activities, apoptosis, molecular modeling and nitric oxide release studies.
    Fadaly WAA; Elshaier YAMM; Hassanein EHM; Abdellatif KRA
    Bioorg Chem; 2020 May; 98():103752. PubMed ID: 32197148
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1,2/5-LOX inhibition and docking study.
    Abdelgawad MA; Labib MB; Abdel-Latif M
    Bioorg Chem; 2017 Oct; 74():212-220. PubMed ID: 28865292
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and biological evaluation of novel 1,2-diaryl-4-substituted-benzylidene-5(4H)-imidazolone derivatives as cytotoxic agents and COX-2/LOX inhibitors.
    Lamie PF; Philoppes JN; Rárová L
    Arch Pharm (Weinheim); 2018 Apr; 351(3-4):e1700311. PubMed ID: 29400411
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and biological evaluation of 1-(4-sulfamylphenyl)-3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors.
    Reddy MV; Billa VK; Pallela VR; Mallireddigari MR; Boominathan R; Gabriel JL; Reddy EP
    Bioorg Med Chem; 2008 Apr; 16(7):3907-16. PubMed ID: 18272371
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and mechanistic study of novel diarylpyrazole derivatives as anti-inflammatory agents with reduced cardiovascular side effects.
    Amin NH; Hamed MIA; Abdel-Fattah MM; Abusabaa AHA; El-Saadi MT
    Bioorg Chem; 2021 Nov; 116():105394. PubMed ID: 34619468
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis, analgesic, anti-inflammatory activity of novel pyrazolones possessing aminosulfonyl pharmacophore as inhibitors of COX-2/5-LOX enzymes: Histopathological and docking studies.
    Abdelgawad MA; Labib MB; Ali WAM; Kamel G; Azouz AA; El-Nahass ES
    Bioorg Chem; 2018 Aug; 78():103-114. PubMed ID: 29550530
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conjugation of 4-aminosalicylate with thiazolinones afforded non-cytotoxic potent in vitro and in vivo anti-inflammatory hybrids.
    Abdu-Allah HHM; Abdelmoez AAB; Tarazi H; El-Shorbagi AA; El-Awady R
    Bioorg Chem; 2020 Jan; 94():103378. PubMed ID: 31677858
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of potential anti-inflammatory drugs: diaryl-1,2,4-triazoles bearing N-hydroxyurea moiety as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase.
    Jiang B; Huang X; Yao H; Jiang J; Wu X; Jiang S; Wang Q; Lu T; Xu J
    Org Biomol Chem; 2014 Apr; 12(13):2114-27. PubMed ID: 24562695
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Benzodioxole-Pyrazole Hybrids as Anti-Inflammatory and Analgesic Agents with COX-1,2/5-LOX Inhibition and Antioxidant Potential.
    Abd El Razik HA; Badr MH; Atta AH; Mouneir SM; Abu-Serie MM
    Arch Pharm (Weinheim); 2017 May; 350(5):. PubMed ID: 28418202
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study.
    El-Miligy MMM; Hazzaa AA; El-Messmary H; Nassra RA; El-Hawash SAM
    Bioorg Chem; 2017 Jun; 72():102-115. PubMed ID: 28390993
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Click chemistry synthesis, biological evaluation and docking study of some novel 2'-hydroxychalcone-triazole hybrids as potent anti-inflammatory agents.
    Boshra AN; Abdu-Allah HHM; Mohammed AF; Hayallah AM
    Bioorg Chem; 2020 Jan; 95():103505. PubMed ID: 31901755
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, cyclooxygenase inhibition, anti-inflammatory evaluation and ulcerogenic liability of new 1,5-diarylpyrazole derivatives.
    Abdellatif KR; Fadaly WA; Ali WA; Kamel GM
    J Enzyme Inhib Med Chem; 2016; 31(sup3):54-60. PubMed ID: 27541738
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel click modifiable thioquinazolinones as anti-inflammatory agents: Design, synthesis, biological evaluation and docking study.
    Moussa G; Alaaeddine R; Alaeddine LM; Nassra R; Belal ASF; Ismail A; El-Yazbi AF; Abdel-Ghany YS; Hazzaa A
    Eur J Med Chem; 2018 Jan; 144():635-650. PubMed ID: 29289887
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of novel hybrids of pyrazole and coumarin as dual inhibitors of COX-2 and 5-LOX.
    Shen FQ; Wang ZC; Wu SY; Ren SZ; Man RJ; Wang BZ; Zhu HL
    Bioorg Med Chem Lett; 2017 Aug; 27(16):3653-3660. PubMed ID: 28720504
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Non-acidic 1,3,4-trisubstituted-pyrazole derivatives as lonazolac analogs with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile.
    Abdellatif KRA; Fadaly WAA; Elshaier YAMM; Ali WAM; Kamel GM
    Bioorg Chem; 2018 Apr; 77():568-578. PubMed ID: 29475165
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dual COX-2 and 15-LOX inhibition study of novel 4-arylidine-2-mercapto-1-phenyl-1H-imidazolidin-5(4H)-ones: Design, synthesis, docking, and anti-inflammatory activity.
    Osman NA; Soltan MK; Rezq S; Flaherty J; Romero DG; Abdelkhalek AS
    Arch Pharm (Weinheim); 2024 May; 357(5):e2300615. PubMed ID: 38315093
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and biological evaluation of novel pyrazole sulfonamide derivatives as dual COX-2/5-LOX inhibitors.
    Gedawy EM; Kassab AE; El Kerdawy AM
    Eur J Med Chem; 2020 Mar; 189():112066. PubMed ID: 31982653
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, biological evaluation and docking study of 1,3,4-thiadiazole-thiazolidinone hybrids as anti-inflammatory agents with dual inhibition of COX-2 and 15-LOX.
    Omar YM; Abdu-Allah HHM; Abdel-Moty SG
    Bioorg Chem; 2018 Oct; 80():461-471. PubMed ID: 29986191
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.