These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 27160179)

  • 1. Modulating non-native aggregation and electrostatic protein-protein interactions with computationally designed single-point mutations.
    O'Brien CJ; Blanco MA; Costanzo JA; Enterline M; Fernandez EJ; Robinson AS; Roberts CJ
    Protein Eng Des Sel; 2016 Jun; 29(6):231-243. PubMed ID: 27160179
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Computational design and biophysical characterization of aggregation-resistant point mutations for γD crystallin illustrate a balance of conformational stability and intrinsic aggregation propensity.
    Sahin E; Jordan JL; Spatara ML; Naranjo A; Costanzo JA; Weiss WF; Robinson AS; Fernandez EJ; Roberts CJ
    Biochemistry; 2011 Feb; 50(5):628-39. PubMed ID: 21184609
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The effect of charge mutations on the stability and aggregation of a human single chain Fv fragment.
    Austerberry JI; Dajani R; Panova S; Roberts D; Golovanov AP; Pluen A; van der Walle CF; Uddin S; Warwicker J; Derrick JP; Curtis R
    Eur J Pharm Biopharm; 2017 Jun; 115():18-30. PubMed ID: 28161552
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Computational Design To Reduce Conformational Flexibility and Aggregation Rates of an Antibody Fab Fragment.
    Zhang C; Samad M; Yu H; Chakroun N; Hilton D; Dalby PA
    Mol Pharm; 2018 Aug; 15(8):3079-3092. PubMed ID: 29897777
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Conformational stability as a design target to control protein aggregation.
    Costanzo JA; O'Brien CJ; Tiller K; Tamargo E; Robinson AS; Roberts CJ; Fernandez EJ
    Protein Eng Des Sel; 2014 May; 27(5):157-67. PubMed ID: 24722670
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Electrostatic origin of in vitro aggregation of human γ-crystallin.
    Mohr BG; Dobson CM; Garman SC; Muthukumar M
    J Chem Phys; 2013 Sep; 139(12):121914. PubMed ID: 24089726
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Investigation of the early stages of human γD-crystallin aggregation process.
    Chang CK; Wang SS; Lo CH; Hsiao HC; Wu JW
    J Biomol Struct Dyn; 2017 Apr; 35(5):1042-1054. PubMed ID: 27025196
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Specific-ion effects on the aggregation mechanisms and protein-protein interactions for anti-streptavidin immunoglobulin gamma-1.
    Barnett GV; Razinkov VI; Kerwin BA; Laue TM; Woodka AH; Butler PD; Perevozchikova T; Roberts CJ
    J Phys Chem B; 2015 May; 119(18):5793-804. PubMed ID: 25885209
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The self assembly of proteins; probing patchy protein interactions.
    James S; Quinn MK; McManus JJ
    Phys Chem Chem Phys; 2015 Feb; 17(7):5413-20. PubMed ID: 25613833
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gamma crystallins of the human eye lens.
    Vendra VP; Khan I; Chandani S; Muniyandi A; Balasubramanian D
    Biochim Biophys Acta; 2016 Jan; 1860(1 Pt B):333-43. PubMed ID: 26116913
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GammaD-crystallin associated protein aggregation and lens fiber cell denucleation.
    Wang K; Cheng C; Li L; Liu H; Huang Q; Xia CH; Yao K; Sun P; Horwitz J; Gong X
    Invest Ophthalmol Vis Sci; 2007 Aug; 48(8):3719-28. PubMed ID: 17652744
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interactions and chaperone function of alphaA-crystallin with T5P gammaC-crystallin mutant.
    Liang JJ
    Protein Sci; 2004 Sep; 13(9):2476-82. PubMed ID: 15322286
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative analysis of human γD-crystallin aggregation under physiological and low pH conditions.
    Wu JW; Chen ME; Wen WS; Chen WA; Li CT; Chang CK; Lo CH; Liu HS; Wang SS
    PLoS One; 2014; 9(11):e112309. PubMed ID: 25389780
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Exploring the aggregation propensity of γS-crystallin protein variants using two-dimensional spectroscopic tools.
    Jiang J; Golchert KJ; Kingsley CN; Brubaker WD; Martin RW; Mukamel S
    J Phys Chem B; 2013 Nov; 117(46):14294-301. PubMed ID: 24219230
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interdomain side-chain interactions in human gammaD crystallin influencing folding and stability.
    Flaugh SL; Kosinski-Collins MS; King J
    Protein Sci; 2005 Aug; 14(8):2030-43. PubMed ID: 16046626
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nonspecific shielding of unfavorable electrostatic intramolecular interactions in the erythropoietin native-state increase conformational stability and limit non-native aggregation.
    Banks DD
    Protein Sci; 2015 May; 24(5):803-11. PubMed ID: 25628168
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel mutation impairing the tertiary structure and stability of γC-crystallin (CRYGC) leads to cataract formation in humans and zebrafish lens.
    Li XQ; Cai HC; Zhou SY; Yang JH; Xi YB; Gao XB; Zhao WJ; Li P; Zhao GY; Tong Y; Bao FC; Ma Y; Wang S; Yan YB; Lu CL; Ma X
    Hum Mutat; 2012 Feb; 33(2):391-401. PubMed ID: 22052681
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Decrease in protein solubility and cataract formation caused by the Pro23 to Thr mutation in human gamma D-crystallin.
    Pande A; Annunziata O; Asherie N; Ogun O; Benedek GB; Pande J
    Biochemistry; 2005 Feb; 44(7):2491-500. PubMed ID: 15709761
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Surface Exposed Free Cysteine Suppresses Crystallization of Human γD-Crystallin.
    Strofaldi A; Khan AR; McManus JJ
    J Mol Biol; 2021 Nov; 433(22):167252. PubMed ID: 34537240
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Electrostatic interactions modulate the differential aggregation propensities of IgG1 and IgG4P antibodies and inform charged residue substitutions for improved developability.
    Heads JT; Lamb R; Kelm S; Adams R; Elliott P; Tyson K; Topia S; West S; Nan R; Turner A; Lawson ADG
    Protein Eng Des Sel; 2019 Dec; 32(6):277-288. PubMed ID: 31868219
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.