333 related articles for article (PubMed ID: 27166223)
1. Impaired protein degradation in FTLD and related disorders.
Götzl JK; Lang CM; Haass C; Capell A
Ageing Res Rev; 2016 Dec; 32():122-139. PubMed ID: 27166223
[TBL] [Abstract][Full Text] [Related]
2. Lysosome dysfunction as a cause of neurodegenerative diseases: Lessons from frontotemporal dementia and amyotrophic lateral sclerosis.
Root J; Merino P; Nuckols A; Johnson M; Kukar T
Neurobiol Dis; 2021 Jul; 154():105360. PubMed ID: 33812000
[TBL] [Abstract][Full Text] [Related]
3. Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis.
Arrant AE; Onyilo VC; Unger DE; Roberson ED
J Neurosci; 2018 Feb; 38(9):2341-2358. PubMed ID: 29378861
[TBL] [Abstract][Full Text] [Related]
4. Common pathobiochemical hallmarks of progranulin-associated frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis.
Götzl JK; Mori K; Damme M; Fellerer K; Tahirovic S; Kleinberger G; Janssens J; van der Zee J; Lang CM; Kremmer E; Martin JJ; Engelborghs S; Kretzschmar HA; Arzberger T; Van Broeckhoven C; Haass C; Capell A
Acta Neuropathol; 2014; 127(6):845-60. PubMed ID: 24619111
[TBL] [Abstract][Full Text] [Related]
5. Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations.
Huang M; Modeste E; Dammer E; Merino P; Taylor G; Duong DM; Deng Q; Holler CJ; Gearing M; Dickson D; Seyfried NT; Kukar T
Acta Neuropathol Commun; 2020 Oct; 8(1):163. PubMed ID: 33028409
[TBL] [Abstract][Full Text] [Related]
6. PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies.
Lee S; Jeon YM; Cha SJ; Kim S; Kwon Y; Jo M; Jang YN; Lee S; Kim J; Kim SR; Lee KJ; Lee SB; Kim K; Kim HJ
Autophagy; 2020 Aug; 16(8):1396-1412. PubMed ID: 31690171
[TBL] [Abstract][Full Text] [Related]
7. Progranulin-mediated deficiency of cathepsin D results in FTD and NCL-like phenotypes in neurons derived from FTD patients.
Valdez C; Wong YC; Schwake M; Bu G; Wszolek ZK; Krainc D
Hum Mol Genet; 2017 Dec; 26(24):4861-4872. PubMed ID: 29036611
[TBL] [Abstract][Full Text] [Related]
8. Is amyotrophic lateral sclerosis/frontotemporal dementia an autophagy disease?
Deng Z; Sheehan P; Chen S; Yue Z
Mol Neurodegener; 2017 Dec; 12(1):90. PubMed ID: 29282133
[TBL] [Abstract][Full Text] [Related]
9. Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by
Holler CJ; Taylor G; Deng Q; Kukar T
eNeuro; 2017; 4(4):. PubMed ID: 28828399
[TBL] [Abstract][Full Text] [Related]
10. Clinicopathological description of two cases with SQSTM1 gene mutation associated with frontotemporal dementia.
Kovacs GG; van der Zee J; Hort J; Kristoferitsch W; Leitha T; Höftberger R; Ströbel T; Van Broeckhoven C; Matej R
Neuropathology; 2016 Feb; 36(1):27-38. PubMed ID: 26234378
[TBL] [Abstract][Full Text] [Related]
11. Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease.
Pottier C; Bieniek KF; Finch N; van de Vorst M; Baker M; Perkersen R; Brown P; Ravenscroft T; van Blitterswijk M; Nicholson AM; DeTure M; Knopman DS; Josephs KA; Parisi JE; Petersen RC; Boylan KB; Boeve BF; Graff-Radford NR; Veltman JA; Gilissen C; Murray ME; Dickson DW; Rademakers R
Acta Neuropathol; 2015 Jul; 130(1):77-92. PubMed ID: 25943890
[TBL] [Abstract][Full Text] [Related]
12. Evidence of a link between ubiquilin 2 and optineurin in amyotrophic lateral sclerosis.
Osaka M; Ito D; Yagi T; Nihei Y; Suzuki N
Hum Mol Genet; 2015 Mar; 24(6):1617-29. PubMed ID: 25398946
[TBL] [Abstract][Full Text] [Related]
13. The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy.
Deneubourg C; Ramm M; Smith LJ; Baron O; Singh K; Byrne SC; Duchen MR; Gautel M; Eskelinen EL; Fanto M; Jungbluth H
Autophagy; 2022 Mar; 18(3):496-517. PubMed ID: 34130600
[TBL] [Abstract][Full Text] [Related]
14. Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis.
Ward ME; Chen R; Huang HY; Ludwig C; Telpoukhovskaia M; Taubes A; Boudin H; Minami SS; Reichert M; Albrecht P; Gelfand JM; Cruz-Herranz A; Cordano C; Alavi MV; Leslie S; Seeley WW; Miller BL; Bigio E; Mesulam MM; Bogyo MS; Mackenzie IR; Staropoli JF; Cotman SL; Huang EJ; Gan L; Green AJ
Sci Transl Med; 2017 Apr; 9(385):. PubMed ID: 28404863
[TBL] [Abstract][Full Text] [Related]
15. Distribution of ubiquilin 2 and TDP-43 aggregates throughout the CNS in UBQLN2 p.T487I-linked amyotrophic lateral sclerosis and frontotemporal dementia.
Nementzik LR; Thumbadoo KM; Murray HC; Gordon D; Yang S; Blair IP; Turner C; Faull RLM; Curtis MA; McLean C; Nicholson GA; Swanson MEV; Scotter EL
Brain Pathol; 2024 May; 34(3):e13230. PubMed ID: 38115557
[TBL] [Abstract][Full Text] [Related]
16. ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway.
Deng Z; Lim J; Wang Q; Purtell K; Wu S; Palomo GM; Tan H; Manfredi G; Zhao Y; Peng J; Hu B; Chen S; Yue Z
Autophagy; 2020 May; 16(5):917-931. PubMed ID: 31362587
[TBL] [Abstract][Full Text] [Related]
17. Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia.
Geier EG; Bourdenx M; Storm NJ; Cochran JN; Sirkis DW; Hwang JH; Bonham LW; Ramos EM; Diaz A; Van Berlo V; Dokuru D; Nana AL; Karydas A; Balestra ME; Huang Y; Russo SP; Spina S; Grinberg LT; Seeley WW; Myers RM; Miller BL; Coppola G; Lee SE; Cuervo AM; Yokoyama JS
Acta Neuropathol; 2019 Jan; 137(1):71-88. PubMed ID: 30382371
[TBL] [Abstract][Full Text] [Related]
18. Investigating the role of filamin C in Belgian patients with frontotemporal dementia linked to GRN deficiency in FTLD-TDP brains.
Janssens J; Philtjens S; Kleinberger G; Van Mossevelde S; van der Zee J; Cacace R; Engelborghs S; Sieben A; Banzhaf-Strathmann J; Dillen L; Merlin C; Cuijt I; Robberecht C; Schmid B; Santens P; Ivanoiu A; Vandenbulcke M; Vandenberghe R; Cras P; De Deyn PP; Martin JJ; Maudsley S; Haass C; Cruts M; Van Broeckhoven C;
Acta Neuropathol Commun; 2015 Nov; 3():68. PubMed ID: 26555887
[TBL] [Abstract][Full Text] [Related]
19. UBQLN2/P62 cellular recycling pathways in amyotrophic lateral sclerosis and frontotemporal dementia.
Fecto F; Siddique T
Muscle Nerve; 2012 Feb; 45(2):157-62. PubMed ID: 22246868
[TBL] [Abstract][Full Text] [Related]
20. Mutations in progranulin (GRN) within the spectrum of clinical and pathological phenotypes of frontotemporal dementia.
van Swieten JC; Heutink P
Lancet Neurol; 2008 Oct; 7(10):965-74. PubMed ID: 18771956
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
