BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

307 related articles for article (PubMed ID: 27173800)

  • 21. Synthesis of Tetrahydrobenzo[
    Mohareb RM; Wardakhan WW; Abbas NS
    Anticancer Agents Med Chem; 2019; 19(14):1737-1753. PubMed ID: 30947678
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Heterocyclization of Thiophenes Derived from Estrone Followed by Cytotoxic, HTRF Kinase and Pim-1 Kinase Evaluations.
    Mahmoud MAA; Mohareb RM; Al-Sharif MA
    Anticancer Agents Med Chem; 2018; 18(12):1711-1728. PubMed ID: 29732981
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Novel benzylidene-thiazolidine-2,4-diones inhibit Pim protein kinase activity and induce cell cycle arrest in leukemia and prostate cancer cells.
    Beharry Z; Zemskova M; Mahajan S; Zhang F; Ma J; Xia Z; Lilly M; Smith CD; Kraft AS
    Mol Cancer Ther; 2009 Jun; 8(6):1473-83. PubMed ID: 19509254
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis of pyrazolo[4,3-a]phenanthridines, a new scaffold for Pim kinase inhibition.
    Suchaud V; Gavara L; Giraud F; Nauton L; Théry V; Anizon F; Moreau P
    Bioorg Med Chem; 2014 Sep; 22(17):4704-10. PubMed ID: 25087047
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Aminothiazolones as potent, selective and cell active inhibitors of the PIM kinase family.
    Quevedo CE; Bataille CJR; Byrne S; Durbin M; Elkins J; Guillermo A; Jones AM; Knapp S; Nadali A; Walker RG; Wilkinson IVL; Wynne GM; Davies SG; Russell AJ
    Bioorg Med Chem; 2020 Nov; 28(22):115724. PubMed ID: 33128909
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Structure-based design of low-nanomolar PIM kinase inhibitors.
    Ishchenko A; Zhang L; Le Brazidec JY; Fan J; Chong JH; Hingway A; Raditsis A; Singh L; Elenbaas B; Hong VS; Marcotte D; Silvian L; Enyedy I; Chao J
    Bioorg Med Chem Lett; 2015 Feb; 25(3):474-80. PubMed ID: 25575657
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Potential roles for the PIM1 kinase in human cancer - a molecular and therapeutic appraisal.
    Shah N; Pang B; Yeoh KG; Thorn S; Chen CS; Lilly MB; Salto-Tellez M
    Eur J Cancer; 2008 Oct; 44(15):2144-51. PubMed ID: 18715779
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Cell-permeable carboxyl-terminal p27(Kip1) peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase.
    Morishita D; Takami M; Yoshikawa S; Katayama R; Sato S; Kukimoto-Niino M; Umehara T; Shirouzu M; Sekimizu K; Yokoyama S; Fujita N
    J Biol Chem; 2011 Jan; 286(4):2681-8. PubMed ID: 21062737
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Discovery of N-substituted 7-azaindoles as Pan-PIM kinases inhibitors - Lead optimization - Part III.
    Barberis C; Pribish J; Tserlin E; Gross A; Czekaj M; Barragué M; Erdman P; Maniar S; Jiang J; Fire L; Patel V; Hebert A; Levit M; Wang A; Sun F; Huang SA
    Bioorg Med Chem Lett; 2019 Feb; 29(3):491-495. PubMed ID: 30553737
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Discovery of imidazopyridazines as potent Pim-1/2 kinase inhibitors.
    Wurz RP; Sastri C; D'Amico DC; Herberich B; Jackson CLM; Pettus LH; Tasker AS; Wu B; Guerrero N; Lipford JR; Winston JT; Yang Y; Wang P; Nguyen Y; Andrews KL; Huang X; Lee MR; Mohr C; Zhang JD; Reid DL; Xu Y; Zhou Y; Wang HL
    Bioorg Med Chem Lett; 2016 Nov; 26(22):5580-5590. PubMed ID: 27769621
    [TBL] [Abstract][Full Text] [Related]  

  • 31. 3D QSAR studies, molecular docking and ADMET evaluation, using thiazolidine derivatives as template to obtain new inhibitors of PIM1 kinase.
    Aouidate A; Ghaleb A; Ghamali M; Ousaa A; Choukrad M; Sbai A; Bouachrine M; Lakhlifi T
    Comput Biol Chem; 2018 Jun; 74():201-211. PubMed ID: 29635214
    [TBL] [Abstract][Full Text] [Related]  

  • 32. PIM1 kinase as a target for cancer therapy.
    Merkel AL; Meggers E; Ocker M
    Expert Opin Investig Drugs; 2012 Apr; 21(4):425-36. PubMed ID: 22385334
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Eco-friendly synthesis of novel cyanopyridine derivatives and their anticancer and PIM-1 kinase inhibitory activities.
    Abouzid KAM; Al-Ansary GH; El-Naggar AM
    Eur J Med Chem; 2017 Jul; 134():357-365. PubMed ID: 28431341
    [TBL] [Abstract][Full Text] [Related]  

  • 34. New Approaches for the Uses of Cyclohexan-1,4-dione for the Synthesis of 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-b]pyridine Derivatives used as Potential Anti-prostate Cancer Agents and Pim-1 Kinase Inhibitors.
    Mohareb RM; Abdo NYM; El-Sharkawy KA
    Anticancer Agents Med Chem; 2018; 18(12):1736-1749. PubMed ID: 29866019
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synthetic cannabinoid quinones: preparation, in vitro antiproliferative effects and in vivo prostate antitumor activity.
    Morales P; Vara D; Goméz-Cañas M; Zúñiga MC; Olea-Azar C; Goya P; Fernández-Ruiz J; Díaz-Laviada I; Jagerovic N
    Eur J Med Chem; 2013; 70():111-9. PubMed ID: 24141201
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Discovery of Dual CDK6/PIM1 Inhibitors with a Novel Structure, High Potency, and Favorable Druggability for the Treatment of Acute Myeloid Leukemia.
    Yuan K; Ji M; Xie S; Qiu Z; Chen W; Min W; Xia F; Zheng M; Wang X; Li J; Hou Y; Kuang W; Wang L; Gu W; Li Z; Yang P
    J Med Chem; 2022 Jan; 65(1):857-875. PubMed ID: 34958208
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Heterocyclization of 2-(2-phenylhydrazono)cyclohexane-1,3-dione to Synthesis Thiophene, Pyrazole and 1,2,4-triazine Derivatives with Anti-Tumor and Tyrosine Kinase Inhibitions.
    Mohareb RM; Alwan ES
    Anticancer Agents Med Chem; 2020; 20(10):1209-1220. PubMed ID: 32156245
    [TBL] [Abstract][Full Text] [Related]  

  • 38. New N-1,N-10-bridged pyrrolo[2,3-a]carbazole-3-carbaldehydes: synthesis and biological activities.
    Giraud F; Bourhis M; Nauton L; Théry V; Herfindal L; Døskeland SO; Anizon F; Moreau P
    Bioorg Chem; 2014 Dec; 57():108-115. PubMed ID: 25305721
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors.
    Pettus LH; Andrews KL; Booker SK; Chen J; Cee VJ; Chavez F; Chen Y; Eastwood H; Guerrero N; Herberich B; Hickman D; Lanman BA; Laszlo J; Lee MR; Lipford JR; Mattson B; Mohr C; Nguyen Y; Norman MH; Powers D; Reed AB; Rex K; Sastri C; Tamayo N; Wang P; Winston JT; Wu B; Wu T; Wurz RP; Xu Y; Zhou Y; Tasker AS; Wang HL
    J Med Chem; 2016 Jul; 59(13):6407-30. PubMed ID: 27285051
    [TBL] [Abstract][Full Text] [Related]  

  • 40. 7-(4H-1,2,4-Triazol-3-yl)benzo[c][2,6]naphthyridines: a novel class of Pim kinase inhibitors with potent cell antiproliferative activity.
    Pierre F; Stefan E; Nédellec AS; Chevrel MC; Regan CF; Siddiqui-Jain A; Macalino D; Streiner N; Drygin D; Haddach M; O'Brien SE; Anderes K; Ryckman DM
    Bioorg Med Chem Lett; 2011 Nov; 21(22):6687-92. PubMed ID: 21982499
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.