BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

381 related articles for article (PubMed ID: 27174644)

  • 1. CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves.
    Martínez-Muriana A; Mancuso R; Francos-Quijorna I; Olmos-Alonso A; Osta R; Perry VH; Navarro X; Gomez-Nicola D; López-Vales R
    Sci Rep; 2016 May; 6():25663. PubMed ID: 27174644
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacological inhibition of CSF1R by GW2580 reduces microglial proliferation and is protective against neuroinflammation and dopaminergic neurodegeneration.
    Neal ML; Fleming SM; Budge KM; Boyle AM; Kim C; Alam G; Beier EE; Wu LJ; Richardson JR
    FASEB J; 2020 Jan; 34(1):1679-1694. PubMed ID: 31914683
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ablation of P2X7 receptor exacerbates gliosis and motoneuron death in the SOD1-G93A mouse model of amyotrophic lateral sclerosis.
    Apolloni S; Amadio S; Montilli C; Volonté C; D'Ambrosi N
    Hum Mol Genet; 2013 Oct; 22(20):4102-16. PubMed ID: 23736299
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tweak regulates astrogliosis, microgliosis and skeletal muscle atrophy in a mouse model of amyotrophic lateral sclerosis.
    Bowerman M; Salsac C; Coque E; Eiselt É; Deschaumes RG; Brodovitch A; Burkly LC; Scamps F; Raoul C
    Hum Mol Genet; 2015 Jun; 24(12):3440-56. PubMed ID: 25765661
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer's-like pathology.
    Olmos-Alonso A; Schetters ST; Sri S; Askew K; Mancuso R; Vargas-Caballero M; Holscher C; Perry VH; Gomez-Nicola D
    Brain; 2016 Mar; 139(Pt 3):891-907. PubMed ID: 26747862
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibiting microglia proliferation after spinal cord injury improves recovery in mice and nonhuman primates.
    Poulen G; Aloy E; Bringuier CM; Mestre-Francés N; Artus EVF; Cardoso M; Perez JC; Goze-Bac C; Boukhaddaoui H; Lonjon N; Gerber YN; Perrin FE
    Theranostics; 2021; 11(18):8640-8659. PubMed ID: 34522204
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Influence of methylene blue on microglia-induced inflammation and motor neuron degeneration in the SOD1(G93A) model for ALS.
    Dibaj P; Zschüntzsch J; Steffens H; Scheffel J; Göricke B; Weishaupt JH; Le Meur K; Kirchhoff F; Hanisch UK; Schomburg ED; Neusch C
    PLoS One; 2012; 7(8):e43963. PubMed ID: 22952827
    [TBL] [Abstract][Full Text] [Related]  

  • 8. System xC- is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice.
    Mesci P; Zaïdi S; Lobsiger CS; Millecamps S; Escartin C; Seilhean D; Sato H; Mallat M; Boillée S
    Brain; 2015 Jan; 138(Pt 1):53-68. PubMed ID: 25384799
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Toll-Like Receptor-4 Inhibitor TAK-242 Attenuates Motor Dysfunction and Spinal Cord Pathology in an Amyotrophic Lateral Sclerosis Mouse Model.
    Fellner A; Barhum Y; Angel A; Perets N; Steiner I; Offen D; Lev N
    Int J Mol Sci; 2017 Aug; 18(8):. PubMed ID: 28763002
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
    Milanese M; Giribaldi F; Melone M; Bonifacino T; Musante I; Carminati E; Rossi PI; Vergani L; Voci A; Conti F; Puliti A; Bonanno G
    Neurobiol Dis; 2014 Apr; 64():48-59. PubMed ID: 24361555
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase.
    Gowing G; Philips T; Van Wijmeersch B; Audet JN; Dewil M; Van Den Bosch L; Billiau AD; Robberecht W; Julien JP
    J Neurosci; 2008 Oct; 28(41):10234-44. PubMed ID: 18842883
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Actions of the antihistaminergic clemastine on presymptomatic SOD1-G93A mice ameliorate ALS disease progression.
    Apolloni S; Fabbrizio P; Amadio S; Volonté C
    J Neuroinflammation; 2016 Aug; 13(1):191. PubMed ID: 27549088
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis.
    Beers DR; Henkel JS; Xiao Q; Zhao W; Wang J; Yen AA; Siklos L; McKercher SR; Appel SH
    Proc Natl Acad Sci U S A; 2006 Oct; 103(43):16021-6. PubMed ID: 17043238
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1
    MacLean M; Juranek J; Cuddapah S; López-Díez R; Ruiz HH; Hu J; Frye L; Li H; Gugger PF; Schmidt AM
    J Neuroinflammation; 2021 Jun; 18(1):139. PubMed ID: 34130712
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Macrophage-mediated inflammation and glial response in the skeletal muscle of a rat model of familial amyotrophic lateral sclerosis (ALS).
    Van Dyke JM; Smit-Oistad IM; Macrander C; Krakora D; Meyer MG; Suzuki M
    Exp Neurol; 2016 Mar; 277():275-282. PubMed ID: 26775178
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Treatment With the CSF1R Antagonist GW2580, Sensitizes Microglia to Reactive Oxygen Species.
    Soto-Diaz K; Vailati-Riboni M; Louie AY; McKim DB; Gaskins HR; Johnson RW; Steelman AJ
    Front Immunol; 2021; 12():734349. PubMed ID: 34899694
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue.
    Vallarola A; Sironi F; Tortarolo M; Gatto N; De Gioia R; Pasetto L; De Paola M; Mariani A; Ghosh S; Watson R; Kalmes A; Bonetto V; Bendotti C
    J Neuroinflammation; 2018 Mar; 15(1):65. PubMed ID: 29495962
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1
    Lee JD; McDonald TS; Fung JNT; Woodruff TM
    Mol Neurobiol; 2020 Oct; 57(10):4143-4155. PubMed ID: 32676989
    [TBL] [Abstract][Full Text] [Related]  

  • 19. H63D HFE genotype accelerates disease progression in animal models of amyotrophic lateral sclerosis.
    Nandar W; Neely EB; Simmons Z; Connor JR
    Biochim Biophys Acta; 2014 Dec; 1842(12 Pt A):2413-26. PubMed ID: 25283820
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PACAP signaling exerts opposing effects on neuroprotection and neuroinflammation during disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
    Ringer C; Büning LS; Schäfer MK; Eiden LE; Weihe E; Schütz B
    Neurobiol Dis; 2013 Jun; 54():32-42. PubMed ID: 23466699
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.