BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 27175734)

  • 1. Tyrosine kinase inhibitor SU11274 increased tumorigenicity and enriched for melanoma-initiating cells by bioenergetic modulation.
    Kucerova L; Demkova L; Skolekova S; Bohovic R; Matuskova M
    BMC Cancer; 2016 May; 16():308. PubMed ID: 27175734
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of c-Met with the specific small molecule tyrosine kinase inhibitor SU11274 decreases growth and metastasis formation of experimental human melanoma.
    Kenessey I; Keszthelyi M; Krámer Z; Berta J; Adám A; Dobos J; Mildner M; Flachner B; Cseh S; Barna G; Szokol B; Orfi L; Kéri G; Döme B; Klepetko W; Tímár J; Tóvári J
    Curr Cancer Drug Targets; 2010 May; 10(3):332-42. PubMed ID: 20370683
    [TBL] [Abstract][Full Text] [Related]  

  • 3. c-Met is a potentially new therapeutic target for treatment of human melanoma.
    Puri N; Ahmed S; Janamanchi V; Tretiakova M; Zumba O; Krausz T; Jagadeeswaran R; Salgia R
    Clin Cancer Res; 2007 Apr; 13(7):2246-53. PubMed ID: 17404109
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Study of critical role of c-Met and its inhibitor SU11274 in colorectal carcinoma.
    Gao W; Bing X; Li M; Yang Z; Li Y; Chen H
    Med Oncol; 2013 Jun; 30(2):546. PubMed ID: 23536000
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The in-vitro spheroid culture induces a more highly differentiated but tumorigenic population from melanoma cell lines.
    Mo J; Sun B; Zhao X; Gu Q; Dong X; Liu Z; Ma Y; Zhao N; Liu Y; Chi J; Sun R
    Melanoma Res; 2013 Aug; 23(4):254-63. PubMed ID: 23752306
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274.
    Hou J; Dong J; Sun L; Geng L; Wang J; Zheng J; Li Y; Bridge J; Hinrichs SH; Ding SJ
    J Transl Med; 2011 May; 9():64. PubMed ID: 21575221
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel targeting of phospho-cMET overcomes drug resistance and induces antitumor activity in multiple myeloma.
    Moschetta M; Basile A; Ferrucci A; Frassanito MA; Rao L; Ria R; Solimando AG; Giuliani N; Boccarelli A; Fumarola F; Coluccia M; Rossini B; Ruggieri S; Nico B; Maiorano E; Ribatti D; Roccaro AM; Vacca A
    Clin Cancer Res; 2013 Aug; 19(16):4371-82. PubMed ID: 23804425
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib.
    Graziani G; Artuso S; De Luca A; Muzi A; Rotili D; Scimeca M; Atzori MG; Ceci C; Mai A; Leonetti C; Levati L; Bonanno E; Tentori L; Caccuri AM
    Biochem Pharmacol; 2015 May; 95(1):16-27. PubMed ID: 25795251
    [TBL] [Abstract][Full Text] [Related]  

  • 9. c-MET as a Potential Therapeutic Target in Ovarian Clear Cell Carcinoma.
    Kim HJ; Yoon A; Ryu JY; Cho YJ; Choi JJ; Song SY; Bang H; Lee JS; Cho WC; Choi CH; Lee JW; Kim BG; Bae DS
    Sci Rep; 2016 Dec; 6():38502. PubMed ID: 27917934
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of ERK-p53 and ERK-mediated phosphorylation of Bcl-2 are involved in autophagic cell death induced by the c-Met inhibitor SU11274 in human lung cancer A549 cells.
    Liu Y; Yang Y; Ye YC; Shi QF; Chai K; Tashiro S; Onodera S; Ikejima T
    J Pharmacol Sci; 2012; 118(4):423-32. PubMed ID: 22466960
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Vemurafenib resistance selects for highly malignant brain and lung-metastasizing melanoma cells.
    Zubrilov I; Sagi-Assif O; Izraely S; Meshel T; Ben-Menahem S; Ginat R; Pasmanik-Chor M; Nahmias C; Couraud PO; Hoon DS; Witz IP
    Cancer Lett; 2015 May; 361(1):86-96. PubMed ID: 25725450
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells.
    Wang CC; Chiang YM; Sung SC; Hsu YL; Chang JK; Kuo PL
    Cancer Lett; 2008 Jan; 259(1):82-98. PubMed ID: 18023967
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase.
    Sattler M; Pride YB; Ma P; Gramlich JL; Chu SC; Quinnan LA; Shirazian S; Liang C; Podar K; Christensen JG; Salgia R
    Cancer Res; 2003 Sep; 63(17):5462-9. PubMed ID: 14500382
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of a c-Met-specific, ATP-competitive small-molecule inhibitor SU11274 on human ovarian carcinoma cell growth, motility, and invasion.
    Koon EC; Ma PC; Salgia R; Welch WR; Christensen JG; Berkowitz RS; Mok SC
    Int J Gynecol Cancer; 2008; 18(5):976-84. PubMed ID: 18021219
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential inhibition sensitivities of MET mutants to the small molecule inhibitor SU11274.
    Zimmer Y; Vaseva AV; Medová M; Streit B; Blank-Liss W; Greiner RH; Schiering N; Aebersold DM
    Cancer Lett; 2010 Mar; 289(2):228-36. PubMed ID: 19783361
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Met receptor inhibitor SU11274 localizes in the endoplasmic reticulum.
    Wiest EJ; Smith HJ; Hollingsworth MA
    Biochem Biophys Res Commun; 2018 Jul; 501(4):858-862. PubMed ID: 29752941
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overexpression of Mcl-1 confers resistance to BRAFV600E inhibitors alone and in combination with MEK1/2 inhibitors in melanoma.
    Fofaria NM; Frederick DT; Sullivan RJ; Flaherty KT; Srivastava SK
    Oncotarget; 2015 Dec; 6(38):40535-56. PubMed ID: 26497853
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Kinase inhibitor screening identifies CDK4 as a potential therapeutic target for melanoma.
    Mahgoub T; Eustace AJ; Collins DM; Walsh N; O'Donovan N; Crown J
    Int J Oncol; 2015 Sep; 47(3):900-8. PubMed ID: 26201960
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A c-Met inhibitor increases the chemosensitivity of cancer stem cells to the irinotecan in gastric carcinoma.
    Yashiro M; Nishii T; Hasegawa T; Matsuzaki T; Morisaki T; Fukuoka T; Hirakawa K
    Br J Cancer; 2013 Nov; 109(10):2619-28. PubMed ID: 24129235
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CD271 Expression on Patient Melanoma Cells Is Unstable and Unlinked to Tumorigenicity.
    Boyle SE; Fedele CG; Corbin V; Wybacz E; Szeto P; Lewin J; Young RJ; Wong A; Fuller R; Spillane J; Speakman D; Donahoe S; Pohl M; Gyorki D; Henderson MA; Johnstone RW; Papenfuss AT; Shackleton M
    Cancer Res; 2016 Jul; 76(13):3965-77. PubMed ID: 27325642
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.