145 related articles for article (PubMed ID: 27178209)
1. Using the fluorescent properties of STO-609 as a tool to assist structure-function analyses of recombinant CaMKK2.
Gerner L; Munack S; Temmerman K; Lawrence-Dörner AM; Besir H; Wilmanns M; Jensen JK; Thiede B; Mills IG; Morth JP
Biochem Biophys Res Commun; 2016 Jul; 476(2):102-7. PubMed ID: 27178209
[TBL] [Abstract][Full Text] [Related]
2. Crystal structure of the Ca²⁺/calmodulin-dependent protein kinase kinase in complex with the inhibitor STO-609.
Kukimoto-Niino M; Yoshikawa S; Takagi T; Ohsawa N; Tomabechi Y; Terada T; Shirouzu M; Suzuki A; Lee S; Yamauchi T; Okada-Iwabu M; Iwabu M; Kadowaki T; Minokoshi Y; Yokoyama S
J Biol Chem; 2011 Jun; 286(25):22570-9. PubMed ID: 21504895
[TBL] [Abstract][Full Text] [Related]
3. Pharmacological inhibition of CaMKK2 with the selective antagonist STO-609 regresses NAFLD.
York B; Li F; Lin F; Marcelo KL; Mao J; Dean A; Gonzales N; Gooden D; Maity S; Coarfa C; Putluri N; Means AR
Sci Rep; 2017 Sep; 7(1):11793. PubMed ID: 28924233
[TBL] [Abstract][Full Text] [Related]
4. Activation of the aryl hydrocarbon receptor by the calcium/calmodulin-dependent protein kinase kinase inhibitor 7-oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid (STO-609).
Monteiro P; Gilot D; Langouet S; Fardel O
Drug Metab Dispos; 2008 Dec; 36(12):2556-63. PubMed ID: 18755850
[TBL] [Abstract][Full Text] [Related]
5. CaMKK2 kinase domain interacts with the autoinhibitory region through the N-terminal lobe including the RP insert.
Kylarova S; Psenakova K; Herman P; Obsilova V; Obsil T
Biochim Biophys Acta Gen Subj; 2018 Oct; 1862(10):2304-2313. PubMed ID: 30053538
[TBL] [Abstract][Full Text] [Related]
6. Hyperactivation of MEK/ERK pathway by Ca
Najar MA; Aravind A; Dagamajalu S; Sidransky D; Ashktorab H; Smoot DT; Gowda H; Prasad TSK; Modi PK; Chatterjee A
Mol Carcinog; 2021 Nov; 60(11):769-783. PubMed ID: 34437731
[TBL] [Abstract][Full Text] [Related]
7. Development and Characterization of Novel Molecular Probes for Ca
Ohtsuka S; Ozeki Y; Fujiwara M; Miyagawa T; Kanayama N; Magari M; Hatano N; Suizu F; Ishikawa T; Tokumitsu H
Biochemistry; 2020 May; 59(17):1701-1710. PubMed ID: 32298102
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of CaMKK2 reverses age-associated decline in bone mass.
Pritchard ZJ; Cary RL; Yang C; Novack DV; Voor MJ; Sankar U
Bone; 2015 Jun; 75():120-7. PubMed ID: 25724145
[TBL] [Abstract][Full Text] [Related]
9. In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds.
O'Byrne SN; Scott JW; Pilotte JR; Santiago ADS; Langendorf CG; Oakhill JS; Eduful BJ; Couñago RM; Wells CI; Zuercher WJ; Willson TM; Drewry DH
Molecules; 2020 Jan; 25(2):. PubMed ID: 31941153
[TBL] [Abstract][Full Text] [Related]
10. Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes.
Eduful BJ; O'Byrne SN; Temme L; Asquith CRM; Liang Y; Picado A; Pilotte JR; Hossain MA; Wells CI; Zuercher WJ; Catta-Preta CMC; Zonzini Ramos P; Santiago AS; Couñago RM; Langendorf CG; Nay K; Oakhill JS; Pulliam TL; Lin C; Awad D; Willson TM; Frigo DE; Scott JW; Drewry DH
J Med Chem; 2021 Aug; 64(15):10849-10877. PubMed ID: 34264658
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of Ca²⁺/calmodulin-dependent protein kinase kinase 2 stimulates osteoblast formation and inhibits osteoclast differentiation.
Cary RL; Waddell S; Racioppi L; Long F; Novack DV; Voor MJ; Sankar U
J Bone Miner Res; 2013 Jul; 28(7):1599-610. PubMed ID: 23408651
[TBL] [Abstract][Full Text] [Related]
12. Ca2+/Calmodulin-Dependent Protein Kinase Kinases (CaMKKs) Effects on AMP-Activated Protein Kinase (AMPK) Regulation of Chicken Sperm Functions.
Nguyen TM; Combarnous Y; Praud C; Duittoz A; Blesbois E
PLoS One; 2016; 11(1):e0147559. PubMed ID: 26808520
[TBL] [Abstract][Full Text] [Related]
13. Role of Ca(2+)/calmodulin-dependent protein kinase kinase in adrenal aldosterone production.
Nanba K; Chen A; Nishimoto K; Rainey WE
Endocrinology; 2015 May; 156(5):1750-6. PubMed ID: 25679868
[TBL] [Abstract][Full Text] [Related]
14. Data for the co-expression and purification of human recombinant CaMKK2 in complex with calmodulin in Escherichia coli.
Gerner L; Munack S; Temmerman K; Lawrence-Dörner AM; Besir H; Wilmanns M; Jensen JK; Thiede B; Mills IG; Morth JP
Data Brief; 2016 Sep; 8():733-40. PubMed ID: 27508226
[TBL] [Abstract][Full Text] [Related]
15. 14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2).
Psenakova K; Petrvalska O; Kylarova S; Lentini Santo D; Kalabova D; Herman P; Obsilova V; Obsil T
Biochim Biophys Acta Gen Subj; 2018 Jul; 1862(7):1612-1625. PubMed ID: 29649512
[TBL] [Abstract][Full Text] [Related]
16. Analysis of Distinct Roles of CaMKK Isoforms Using STO-609-Resistant Mutants in Living Cells.
Fujiwara Y; Hiraoka Y; Fujimoto T; Kanayama N; Magari M; Tokumitsu H
Biochemistry; 2015 Jun; 54(25):3969-77. PubMed ID: 26050738
[TBL] [Abstract][Full Text] [Related]
17. STO-609, a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase.
Tokumitsu H; Inuzuka H; Ishikawa Y; Ikeda M; Saji I; Kobayashi R
J Biol Chem; 2002 May; 277(18):15813-8. PubMed ID: 11867640
[TBL] [Abstract][Full Text] [Related]
18. Akt activation by Ca
Gocher AM; Azabdaftari G; Euscher LM; Dai S; Karacosta LG; Franke TF; Edelman AM
J Biol Chem; 2017 Aug; 292(34):14188-14204. PubMed ID: 28634229
[TBL] [Abstract][Full Text] [Related]
19. CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle.
Negoita F; Addinsall AB; Hellberg K; Bringas CF; Hafen PS; Sermersheim TJ; Agerholm M; Lewis CTA; Ahwazi D; Ling NXY; Larsen JK; Deshmukh AS; Hossain MA; Oakhill JS; Ochala J; Brault JJ; Sankar U; Drewry DH; Scott JW; Witczak CA; Sakamoto K
Mol Metab; 2023 Sep; 75():101761. PubMed ID: 37380024
[TBL] [Abstract][Full Text] [Related]
20. Binding and structural analyses of potent inhibitors of the human Ca
Profeta GS; Dos Reis CV; Santiago ADS; Godoi PHC; Fala AM; Wells CI; Sartori R; Salmazo APT; Ramos PZ; Massirer KB; Elkins JM; Drewry DH; Gileadi O; Couñago RM
Sci Rep; 2019 Nov; 9(1):16452. PubMed ID: 31712618
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
