These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

283 related articles for article (PubMed ID: 27179792)

  • 21. Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts.
    Vetrivel KS; Meckler X; Chen Y; Nguyen PD; Seidah NG; Vassar R; Wong PC; Fukata M; Kounnas MZ; Thinakaran G
    J Biol Chem; 2009 Feb; 284(6):3793-803. PubMed ID: 19074428
    [TBL] [Abstract][Full Text] [Related]  

  • 22. CD2-associated protein (CD2AP) overexpression accelerates amyloid precursor protein (APP) transfer from early endosomes to the lysosomal degradation pathway.
    Furusawa K; Takasugi T; Chiu YW; Hori Y; Tomita T; Fukuda M; Hisanaga SI
    J Biol Chem; 2019 Jul; 294(28):10886-10899. PubMed ID: 31138646
    [TBL] [Abstract][Full Text] [Related]  

  • 23. BACE1 in Alzheimer's disease.
    Sathya M; Premkumar P; Karthick C; Moorthi P; Jayachandran KS; Anusuyadevi M
    Clin Chim Acta; 2012 Dec; 414():171-8. PubMed ID: 22926063
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Aβ1-42-mediated down-regulation of Uch-L1 is dependent on NF-κB activation and impaired BACE1 lysosomal degradation.
    Guglielmotto M; Monteleone D; Boido M; Piras A; Giliberto L; Borghi R; Vercelli A; Fornaro M; Tabaton M; Tamagno E
    Aging Cell; 2012 Oct; 11(5):834-44. PubMed ID: 22726800
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Cdk5 protein inhibition and Aβ42 increase BACE1 protein level in primary neurons by a post-transcriptional mechanism: implications of CDK5 as a therapeutic target for Alzheimer disease.
    Sadleir KR; Vassar R
    J Biol Chem; 2012 Mar; 287(10):7224-35. PubMed ID: 22223639
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Aberrant proteolytic processing and therapeutic strategies in Alzheimer disease.
    Tomita T
    Adv Biol Regul; 2017 May; 64():33-38. PubMed ID: 28082052
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Β-site APP-cleaving enzyme 1 trafficking and Alzheimer's disease pathogenesis.
    Tan J; Evin G
    J Neurochem; 2012 Mar; 120(6):869-80. PubMed ID: 22171895
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells.
    Chen LM; Lin ZY; Zhu YG; Lin N; Zhang J; Pan XD; Chen XC
    Eur J Pharmacol; 2012 Jan; 675(1-3):15-21. PubMed ID: 22166376
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Deficiency of Neuronal p38α MAPK Attenuates Amyloid Pathology in Alzheimer Disease Mouse and Cell Models through Facilitating Lysosomal Degradation of BACE1.
    Schnöder L; Hao W; Qin Y; Liu S; Tomic I; Liu X; Fassbender K; Liu Y
    J Biol Chem; 2016 Jan; 291(5):2067-79. PubMed ID: 26663083
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Promotion of BACE1 mRNA alternative splicing reduces amyloid beta-peptide production.
    Mowrer KR; Wolfe MS
    J Biol Chem; 2008 Jul; 283(27):18694-701. PubMed ID: 18468996
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Systemic administration of fibroblast growth factor-2 (FGF2) reduces BACE1 expression and amyloid pathology in APP23 mice.
    Katsouri L; Ashraf A; Birch AM; Lee KK; Mirzaei N; Sastre M
    Neurobiol Aging; 2015 Feb; 36(2):821-31. PubMed ID: 25457554
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease.
    Chen CH; Zhou W; Liu S; Deng Y; Cai F; Tone M; Tone Y; Tong Y; Song W
    Int J Neuropsychopharmacol; 2012 Feb; 15(1):77-90. PubMed ID: 21329555
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models.
    Martiskainen H; Viswanathan J; Nykänen NP; Kurki M; Helisalmi S; Natunen T; Sarajärvi T; Kurkinen KM; Pursiheimo JP; Rauramaa T; Alafuzoff I; Jääskeläinen JE; Leinonen V; Soininen H; Haapasalo A; Huttunen HJ; Hiltunen M
    Neurobiol Aging; 2015 Feb; 36(2):1221.e15-28. PubMed ID: 25281018
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Swedish mutant APP-based BACE1 binding site peptide reduces APP β-cleavage and cerebral Aβ levels in Alzheimer's mice.
    Li S; Hou H; Mori T; Sawmiller D; Smith A; Tian J; Wang Y; Giunta B; Sanberg PR; Zhang S; Tan J
    Sci Rep; 2015 Jun; 5():11322. PubMed ID: 26091071
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Dysregulation of intracellular trafficking and endosomal sorting in Alzheimer's disease: controversies and unanswered questions.
    Toh WH; Gleeson PA
    Biochem J; 2016 Jul; 473(14):1977-93. PubMed ID: 27407168
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Snapin-mediated BACE1 retrograde transport is essential for its degradation in lysosomes and regulation of APP processing in neurons.
    Ye X; Cai Q
    Cell Rep; 2014 Jan; 6(1):24-31. PubMed ID: 24373968
    [TBL] [Abstract][Full Text] [Related]  

  • 38. LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.
    Majercak J; Ray WJ; Espeseth A; Simon A; Shi XP; Wolffe C; Getty K; Marine S; Stec E; Ferrer M; Strulovici B; Bartz S; Gates A; Xu M; Huang Q; Ma L; Shughrue P; Burchard J; Colussi D; Pietrak B; Kahana J; Beher D; Rosahl T; Shearman M; Hazuda D; Sachs AB; Koblan KS; Seabrook GR; Stone DJ
    Proc Natl Acad Sci U S A; 2006 Nov; 103(47):17967-72. PubMed ID: 17098871
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Flotillins bind to the dileucine sorting motif of β-site amyloid precursor protein-cleaving enzyme 1 and influence its endosomal sorting.
    John BA; Meister M; Banning A; Tikkanen R
    FEBS J; 2014 Apr; 281(8):2074-87. PubMed ID: 24612608
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A GPCR/secretase complex regulates beta- and gamma-secretase specificity for Abeta production and contributes to AD pathogenesis.
    Teng L; Zhao J; Wang F; Ma L; Pei G
    Cell Res; 2010 Feb; 20(2):138-53. PubMed ID: 20066010
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.