BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

81 related articles for article (PubMed ID: 27180429)

  • 1. RECEPTOR AFFINITY AND PHOSPHODIESTERASES 4B AND 10A ACTIVITY OF OCTAHYDRO- AND 6,7-DIMETHOXY-3,4-DIHYDRO- ISOQUINOLIN-2(1H)-YL-ALKYL DERIVATIVES OF IMIDAZO- AND PYRIMIDINO[2,1-f]PURINES.
    Zagórska A; Gryzło B; Satała G; Bojarski AJ; Głuch-Lutwin M; Mordyl B; Kazek G; Pawłowski M
    Acta Pol Pharm; 2016; 73(2):369-77. PubMed ID: 27180429
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological evaluation of 2-fluoro and 3-trifluoromethyl-phenyl-piperazinylalkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione as potential antidepressant agents.
    Zagórska A; Bucki A; Kołaczkowski M; Siwek A; Głuch-Lutwin M; Starowicz G; Kazek G; Partyka A; Wesołowska A; Słoczyńska K; Pękala E; Pawłowski M
    J Enzyme Inhib Med Chem; 2016; 31(sup3):10-24. PubMed ID: 27353547
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characteristics of metabolic stability and the cell permeability of 2-pyrimidinyl-piperazinyl-alkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione with antidepressant- and anxiolytic-like activities.
    Zagórska A; Partyka A; Bucki A; Kołaczkowski M; Jastrzębska-Więsek M; Czopek A; Siwek A; Głuch-Lutwin M; Bednarski M; Bajda M; Jończyk J; Piska K; Koczurkiewicz P; Wesołowska A; Pawłowski M
    Chem Biol Drug Des; 2019 Apr; 93(4):511-521. PubMed ID: 30422400
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and preliminary pharmacological evaluation of imidazo[2,1-f]purine-2,4-dione derivatives.
    Zagórska A; Jurczyk S; Pawłowski M; Dybała M; Nowak G; Tatarczyńska E; Nikiforuk A; Chojnacka-Wójcik E
    Eur J Med Chem; 2009 Nov; 44(11):4288-96. PubMed ID: 19679379
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New arylpiperazinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and dihydro[1,3]oxazolo[2,3-f]purinedione targeting the serotonin 5-HT1A /5-HT2A /5-HT7 and dopamine D2 receptors.
    Chłoń-Rzepa G; Zagórska A; Bucki A; Kołaczkowski M; Pawłowski M; Satała G; Bojarski AJ; Partyka A; Wesołowska A; Pękala E; Słoczyńska K
    Arch Pharm (Weinheim); 2015 Apr; 348(4):242-53. PubMed ID: 25773907
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-5-HT receptor affinity relationship in a new group of 7-arylpiperazynylalkyl and 7-tetrahydroisoquinolinylalkyl derivatives of 8-amino-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione.
    Żmudzki P; Chłoń-Rzepa G; Bojarski AJ; Zygmunt M; Kazek G; Mordyl B; Pawłowski M
    Arch Pharm (Weinheim); 2015 Apr; 348(4):229-41. PubMed ID: 25773578
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Impact of N-Alkylamino Substituents on Serotonin Receptor (5-HTR) Affinity and Phosphodiesterase 10A (PDE10A) Inhibition of Isoindole-1,3-dione Derivatives.
    Czopek A; Partyka A; Bucki A; Pawłowski M; Kołaczkowski M; Siwek A; Głuch-Lutwin M; Koczurkiewicz P; Pękala E; Jaromin A; Tyliszczak B; Wesołowska A; Zagórska A
    Molecules; 2020 Aug; 25(17):. PubMed ID: 32854402
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-5-HT/D
    Żmudzki P; Satała G; Chłoń-Rzepa G; Bojarski AJ; Kazek G; Siwek A; Gryboś A; Głuch-Lutwin M; Wesołowska A; Pawłowski M
    Arch Pharm (Weinheim); 2016 Oct; 349(10):774-784. PubMed ID: 27510801
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-activity relationships and molecular studies of novel arylpiperazinylalkyl purine-2,4-diones and purine-2,4,8-triones with antidepressant and anxiolytic-like activity.
    Zagórska A; Kołaczkowski M; Bucki A; Siwek A; Kazek G; Satała G; Bojarski AJ; Partyka A; Wesołowska A; Pawłowski M
    Eur J Med Chem; 2015 Jun; 97():142-54. PubMed ID: 25965777
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxamides with selective affinity for the 5-HT(4) receptor: synthesis and structure-affinity and structure-activity relationships of a new series of partial agonist and antagonist derivatives.
    Tapia I; Alonso-Cires L; López-Tudanca PL; Mosquera R; Labeaga L; Innerárity A; Orjales A
    J Med Chem; 1999 Jul; 42(15):2870-80. PubMed ID: 10425096
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 7-Arylpiperazinylalkyl and 7-tetrahydroisoquinolinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and some of their purine-2,6,8-trione analogs as 5-HT(1A), 5-HT(2A), and 5-HT(7) serotonin receptor ligands.
    Chłoń-Rzepa G; Zmudzki P; Zajdel P; Bojarski AJ; Duszyńska B; Nikiforuk A; Tatarczyńska E; Pawłowski M
    Bioorg Med Chem; 2007 Aug; 15(15):5239-50. PubMed ID: 17517514
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activity.
    Hirokawa Y; Fujiwara I; Suzuki K; Harada H; Yoshikawa T; Yoshida N; Kato S
    J Med Chem; 2003 Feb; 46(5):702-15. PubMed ID: 12593651
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 8-(1H-imidazol-1-yl)-7-nitro-4(5H)-imidazo[1,2-alpha]quinoxalinone and related compounds: synthesis and structure-activity relationships for the AMPA-type non-NMDA receptor.
    Ohmori J; Shimizu-Sasamata M; Okada M; Sakamoto S
    J Med Chem; 1997 Jun; 40(13):2053-63. PubMed ID: 9207947
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A3 adenosine receptor antagonists.
    Baraldi PG; Preti D; Tabrizi MA; Fruttarolo F; Romagnoli R; Zaid NA; Moorman AR; Merighi S; Varani K; Borea PA
    J Med Chem; 2005 Jul; 48(14):4697-701. PubMed ID: 16000006
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 1-(Arylsulfonyl)-2,3-dihydro-1H-quinolin-4-one derivatives as 5-HT(6) serotonin receptor ligands.
    Park CM; Choi JI; Choi JH; Kim SY; Park WK; Seong CM
    Bioorg Med Chem Lett; 2011 Jan; 21(2):698-703. PubMed ID: 21190848
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacology of JNJ-42314415, a centrally active phosphodiesterase 10A (PDE10A) inhibitor: a comparison of PDE10A inhibitors with D2 receptor blockers as potential antipsychotic drugs.
    Megens AA; Hendrickx HM; Hens KA; Fonteyn I; Langlois X; Lenaerts I; Somers MV; de Boer P; Vanhoof G
    J Pharmacol Exp Ther; 2014 Apr; 349(1):138-54. PubMed ID: 24421319
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and structure-activity relationships of a new model of arylpiperazines. 4. 1-[omega-(4-Arylpiperazin-1-yl)alkyl]-3-(diphenylmethylene) - 2, 5-pyrrolidinediones and -3-(9H-fluoren-9-ylidene)-2, 5-pyrrolidinediones: study of the steric requirements of the terminal amide fragment on 5-HT1A affinity/selectivity.
    López-Rodríguez ML; Morcillo MJ; Rovat TK; Fernández E; Vicente B; Sanz AM; Hernández M; Orensanz L
    J Med Chem; 1999 Jan; 42(1):36-49. PubMed ID: 9888831
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High affinity and selectivity of [[(arylpiperazinyl)alkyl]thio]thieno[2,3-d]pyrimidinone derivatives for the 5-HT(1A) receptor. Synthesis and structure-affinity relationships.
    Modica M; Santagati M; Russo F; Selvaggini C; Cagnotto A; Mennini T
    Eur J Med Chem; 2000; 35(7-8):677-89. PubMed ID: 10960183
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Serotonin 5-HT2 receptor, dopamine D2 receptor, and alpha 1 adrenoceptor antagonists. Conformationally flexible analogues of the atypical antipsychotic sertindole.
    Andersen K; Liljefors T; Hyttel J; Perregaard J
    J Med Chem; 1996 Sep; 39(19):3723-38. PubMed ID: 8809161
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New arylpiperazine 5-HT(1A) receptor ligands containing the pyrimido[2,1-f]purine fragment: synthesis, in vitro, and in vivo pharmacological evaluation.
    Jurczyk S; Kołaczkowski M; Maryniak E; Zajdel P; Pawłowski M; Tatarczyńska E; Kłodzińska A; Chojnacka-Wójcik E; Bojarski AJ; Charakchieva-Minol S; Duszyńska B; Nowak G; Maciag D
    J Med Chem; 2004 May; 47(10):2659-66. PubMed ID: 15115407
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.