544 related articles for article (PubMed ID: 27211901)
1. Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway.
Ducker GS; Chen L; Morscher RJ; Ghergurovich JM; Esposito M; Teng X; Kang Y; Rabinowitz JD
Cell Metab; 2016 Jun; 23(6):1140-1153. PubMed ID: 27211901
[TBL] [Abstract][Full Text] [Related]
2. Quantitative flux analysis reveals folate-dependent NADPH production.
Fan J; Ye J; Kamphorst JJ; Shlomi T; Thompson CB; Rabinowitz JD
Nature; 2014 Jun; 510(7504):298-302. PubMed ID: 24805240
[TBL] [Abstract][Full Text] [Related]
3. Cellular Pharmacodynamics of a Novel Pyrrolo[3,2-
Dekhne AS; Ning C; Nayeen MJ; Shah K; Kalpage H; Frühauf J; Wallace-Povirk A; O'Connor C; Hou Z; Kim S; Hüttemann M; Gangjee A; Matherly LH
Mol Pharmacol; 2020 Jan; 97(1):9-22. PubMed ID: 31707355
[TBL] [Abstract][Full Text] [Related]
4. Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability.
Lee WD; Pirona AC; Sarvin B; Stern A; Nevo-Dinur K; Besser E; Sarvin N; Lagziel S; Mukha D; Raz S; Aizenshtein E; Shlomi T
Cell Metab; 2021 Jan; 33(1):190-198.e6. PubMed ID: 33326752
[TBL] [Abstract][Full Text] [Related]
5. Mitochondrial translation requires folate-dependent tRNA methylation.
Morscher RJ; Ducker GS; Li SH; Mayer JA; Gitai Z; Sperl W; Rabinowitz JD
Nature; 2018 Feb; 554(7690):128-132. PubMed ID: 29364879
[TBL] [Abstract][Full Text] [Related]
6. Tracing Metabolic Fate of Mitochondrial Glycine Cleavage System Derived Formate In Vitro and In Vivo.
Tan YL; Sou NL; Tang FY; Ko HA; Yeh WT; Peng JH; Chiang EI
Int J Mol Sci; 2020 Nov; 21(22):. PubMed ID: 33233834
[TBL] [Abstract][Full Text] [Related]
7. Therapeutic Targeting of Mitochondrial One-Carbon Metabolism in Cancer.
Dekhne AS; Hou Z; Gangjee A; Matherly LH
Mol Cancer Ther; 2020 Nov; 19(11):2245-2255. PubMed ID: 32879053
[TBL] [Abstract][Full Text] [Related]
8. Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2.
Nishimura T; Nakata A; Chen X; Nishi K; Meguro-Horike M; Sasaki S; Kita K; Horike SI; Saitoh K; Kato K; Igarashi K; Murayama T; Kohno S; Takahashi C; Mukaida N; Yano S; Soga T; Tojo A; Gotoh N
Oncogene; 2019 Apr; 38(14):2464-2481. PubMed ID: 30532069
[TBL] [Abstract][Full Text] [Related]
9. 13C NMR detection of folate-mediated serine and glycine synthesis in vivo in Saccharomyces cerevisiae.
Pasternack LB; Laude DA; Appling DR
Biochemistry; 1992 Sep; 31(37):8713-9. PubMed ID: 1390656
[TBL] [Abstract][Full Text] [Related]
10. Deletion of the neural tube defect-associated gene
Bryant JD; Sweeney SR; Sentandreu E; Shin M; Ipas H; Xhemalce B; Momb J; Tiziani S; Appling DR
J Biol Chem; 2018 Apr; 293(16):5821-5833. PubMed ID: 29483189
[TBL] [Abstract][Full Text] [Related]
11. Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs.
Minton DR; Nam M; McLaughlin DJ; Shin J; Bayraktar EC; Alvarez SW; Sviderskiy VO; Papagiannakopoulos T; Sabatini DM; Birsoy K; Possemato R
Mol Cell; 2018 Feb; 69(4):610-621.e5. PubMed ID: 29452640
[TBL] [Abstract][Full Text] [Related]
12. Serine hydroxymethyltransferase: a key player connecting purine, folate and methionine metabolism in Saccharomyces cerevisiae.
Saint-Marc C; Hürlimann HC; Daignan-Fornier B; Pinson B
Curr Genet; 2015 Nov; 61(4):633-40. PubMed ID: 25893566
[TBL] [Abstract][Full Text] [Related]
13. Role of mitochondrial and cytoplasmic serine hydroxymethyltransferase isozymes in de novo purine synthesis in Saccharomyces cerevisiae.
Kastanos EK; Woldman YY; Appling DR
Biochemistry; 1997 Dec; 36(48):14956-64. PubMed ID: 9398220
[TBL] [Abstract][Full Text] [Related]
14. One-carbon metabolism in Neurospora crassa wild-type and in mutants partially deficient in serine hydroxymethyltransferase.
Cossins EA; Chan PY; Combepine G
Biochem J; 1976 Nov; 160(2):305-14. PubMed ID: 137722
[TBL] [Abstract][Full Text] [Related]
15. The one-carbon metabolism pathway highlights therapeutic targets for gastrointestinal cancer (Review).
Konno M; Asai A; Kawamoto K; Nishida N; Satoh T; Doki Y; Mori M; Ishii H
Int J Oncol; 2017 Apr; 50(4):1057-1063. PubMed ID: 28259896
[TBL] [Abstract][Full Text] [Related]
16. Whole-cell detection by 13C NMR of metabolic flux through the C1-tetrahydrofolate synthase/serine hydroxymethyltransferase enzyme system and effect of antifolate exposure in Saccharomyces cerevisiae.
Pasternack LB; Laude DA; Appling DR
Biochemistry; 1994 Jun; 33(23):7166-73. PubMed ID: 8003483
[TBL] [Abstract][Full Text] [Related]
17. In silico experimentation with a model of hepatic mitochondrial folate metabolism.
Nijhout HF; Reed MC; Lam SL; Shane B; Gregory JF; Ulrich CM
Theor Biol Med Model; 2006 Dec; 3():40. PubMed ID: 17150100
[TBL] [Abstract][Full Text] [Related]
18. Investigating the regulation of one-carbon metabolism in Arabidopsis thaliana.
Li R; Moore M; King J
Plant Cell Physiol; 2003 Mar; 44(3):233-41. PubMed ID: 12668769
[TBL] [Abstract][Full Text] [Related]
19. Novel Pyrrolo[3,2-
Dekhne AS; Shah K; Ducker GS; Katinas JM; Wong-Roushar J; Nayeen MJ; Doshi A; Ning C; Bao X; Frühauf J; Liu J; Wallace-Povirk A; O'Connor C; Dzinic SH; White K; Kushner J; Kim S; Hüttemann M; Polin L; Rabinowitz JD; Li J; Hou Z; Dann CE; Gangjee A; Matherly LH
Mol Cancer Ther; 2019 Oct; 18(10):1787-1799. PubMed ID: 31289137
[TBL] [Abstract][Full Text] [Related]
20. Role of cytosolic serine hydroxymethyltransferase in one-carbon metabolism in Neurospora crassa.
Jeong SS; Schirch V
Arch Biochem Biophys; 1996 Nov; 335(2):333-41. PubMed ID: 8914930
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
